Search results for "Null"

Enhanced proinflammatory response to the Candida albicans gpi7 null mutant by murine cells.

2008

International audience; The Candida albicans gpi7/gpi7 null mutant strain (Deltagpi7), which is affected in glycosylphosphatidylinositol (GPI) anchor biosynthesis, showed a reduced virulence following systemic infection of C57BL/6 mice. In vitro production of TNF-alpha, IL-6 and IL-1beta by macrophages in response to Deltagpi7 cells was significantly increased as compared to control (wild type GPI7/GPI7 and revertant gpi7/GPI7) cells; this probably contributes to the enhanced recruitment of neutrophils to the peritoneal cavity in response to Deltagpi7 cells. Survival of knockout mice for Toll-like receptor (TLR) 2 and TLR4 following intravenous injection of Deltagpi7 cells showed no signifi…

MOTIVI E MOTIVAZIONE, FORMA E FORMALISMO: MINIMUM MOTIVO DEL PROVVEDIMENTO E MINIMUM COGNITORIO DEL GIUDIZIO AMMINISTRATIVO DI LEGITTIMITÀ. (NOTA A C…

2010

Arithmetic visibility estimates for OECD countries with three government levels

2003

The importance of fiscal visibility has been well known for a long time but attempts to quantify it by taking the internal structure of every type of revenue and expenditure in a fiscal system into consideration are recent. Indicators used until now rest on structural parameters combined in a multiplicative way with a 0 estimate always resulting in at least one of such factors being null. An alternative way to measure fiscal visibility consists of combining parametric values in an additive instead of a multiplicative form. Calculations can then show estimates which are much more sensitive to the initial values. The aim of this contribution is to present new additive indicators that are appl…

Threshold cointegration and nonlinear adjustment between goods and services inflation in the United States

2006

In this paper, we model the long-run relationship between goods and services inflation for the United States over the period 1968:1–2003:3. Our empirical methodology makes use of recent developments on threshold cointegration that consider the possibility of a nonlinear relationship between the two inflation series. According to our results, the null hypothesis of linear cointegration would be rejected in favor of a two-regime threshold cointegration model. Consequently, we could expect a cointegrating relationship only when the divergence between services inflation and goods inflation is above the threshold point estimate.

Paradossi dell’eloquenza senza tempo: Elogio di Nulla/Elogio di Qualcosa

2011

Nulla è dunque più importante di Nulla, un personaggio impalpabile e invisibile, di cui tuttavia percepiamo la presenza, quasi che il significato di questa parola nascondesse un fondo affermativo che solo l’acutezza della scrittura paradossale riesce a far riemergere, negando la nullità del Nulla, ovvero affermandone l’insospettabile consistenza.

Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes

2004

International audience; Peroxisome proliferator-activated receptor alpha (PPARa) activation by fibrates controls expression of several genes involved in hepatic cholesterol metabolism. Other genes could be indirectly controlled in response to changes in cellular cholesterol availability. To further understand how fibrates may affect cholesterol synthesis, we investigated in parallel the changes in the metabolic pathways contributing to cholesterol homeostasis in liver. Ciprofibrate increased HMG-CoA reductase and FPP synthase mRNA levels in rat hepatocytes, together with cholesterogenesis from [14C] acetate and [3H] mevalonate. The up-regulation observed in fenofibrate- and WY-14,643-treate…

Hypertrophic pyloric stenosis masked by kidney failure in a male infant with a contiguous gene deletion syndrome at Xp22.31 involving the steroid sul…

2022

Abstract Background Contiguous gene deletion syndrome at Xp22.3 resulting in nullisomy in males or Turner syndrome patients typically encompasses the steroid sulfatase gene (STS) and contiguously located other genes expanding the phenotype. In large deletions, that encompass also the Kallmann syndrome 1 gene (KAL1), occasionally infantile hypertrophic pyloric stenosis (IHPS) and congenital anomalies of the kidney and urinary tract (CAKUT) have been reported. Patient presentation We report on a male newborn with family history in maternal uncle of renal abnormalities and short stature still without ichthyosiform dermatosis. The baby presented CAKUT with kidney failure and progressive vomitin…

When Geometry Constrains Vision: Systematic Misperceptions within Geometrical Configurations.

2016

International audience; How accurate are we in reproducing a point within a simple shape? This is the empirical question we addressed in this work. Participants were presented with a tiny disk embedded in an empty circle (Experiment 1 and 3) or in a square (Experiment 2). Shortly afterwards the disk vanished and they had to reproduce the previously seen disk position within the empty shape by means of the mouse cursor, as accurately as possible. Several loci inside each shape were tested. We found that the space delimited by a circle and by a square is not homogeneous and the observed distortion appears to be consistent across observers and specific for the two tested shapes. However, a com…

Relative Age Effect in the Sport Environment. Role of Physical Fitness and Cognitive Function in Youth Soccer Players

2019

The need to achieve short-term competitive outcomes in sports may influence the emergence of talent selection strategies, which could bias individuals&rsquo

Evidence for an Association between Post-Fledging Dispersal and Microsatellite Multilocus Heterozygosity in a Large Population of Greater Flamingos

2013

10 pages; International audience; DISPERSAL CAN BE DIVIDED INTO THREE STAGES: departure, transience and settlement. Despite the fact that theoretical studies have emphasized the importance of heterozygosity on dispersal strategies, empirical evidence of its effect on different stages of dispersal is lacking. Here, using multi-event capture-mark-recapture models, we show a negative association between microsatellite multilocus heterozygosity (MLH; 10 loci; n = 1023) and post-fledging dispersal propensity for greater flamingos, Phoenicopterus roseus, born in southern France. We propose that the negative effects of inbreeding depression affects competitive ability and therefore more homozygous…