Search results for "Nullcline"

showing 2 items of 2 documents

Remarks on GRN-type systems

2020

Systems of ordinary differential equations that appear in gene regulatory networks theory are considered. We are focused on asymptotical behavior of solutions. There are stable critical points as well as attractive periodic solutions in two-dimensional and three-dimensional systems. Instead of considering multiple parameters (10 in a two-dimensional system) we focus on typical behaviors of nullclines. Conclusions about possible attractors are made.

0301 basic medicineComputer sciencelcsh:RGeneral EngineeringGene regulatory networkattractorslcsh:MedicineType (model theory)Nullcline03 medical and health sciences030104 developmental biology0302 clinical medicineordinary differential equations030220 oncology & carcinogenesisOrdinary differential equationAttractorgenetic regulatory networksApplied mathematicslcsh:Qlcsh:ScienceFocus (optics)4open
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A Nullclines Approach to the Study of 2D Artificial Network

2019


 
 The system of two the first order ordinary differential equations arising in the gene regulatory networks theory is studied. The structure of attractors for this system is described for three important behavioral cases: activation, inhibition, mixed activation-inhibition. The geometrical approach combined with the vector field analysis allows treating the problem in full generality. A number of propositions are stated and the proof is geometrical, avoiding complex analytic. Although not all the possible cases are considered, the instructions are given what to do in any particular situation.

GeneralityPhase portraitOrdinary differential equationAttractorStructure (category theory)Gene regulatory networkApplied mathematicsVector fieldGeneral MedicineGeneral ChemistryNullclineMathematicsContemporary Mathematics
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