Search results for "Numa"
showing 4 items of 74 documents
Long-term safety of nine systemic medications for psoriasis: A cohort study using the Spanish Registry of Adverse Events for Biological Therapy in De…
2020
Background: Registry studies broadly describing the safety of systemic drugs in psoriasis are needed. Objective: To describe the safety findings of the systemic drugs acitretin, adalimumab, apremilast, cyclosporine, etanercept, infliximab, methotrexate, secukinumab, and ustekinumab used for the treatment of moderate to severe psoriasis in patients included in the Spanish Registry of Adverse Events for Biological Therapy in Dermatological Diseases (BIOBADADERM) Registry. Methods: The incidence rate ratio (IRR) and adjusted IRR (including propensity scores) of identified adverse events for each drug, using methotrexate as reference, were determined by means of a prospective cohort. Results: O…
Safety and potential interaction of immunosuppressive drugs for the treatment of inflammatory bowel disease in elderly patients
2021
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are chronic diseases associated with increased morbidity and reduced quality of life. Age may represent a risk factor for adverse events, due to the multimorbidity and polypharmacy, common in elderly patients. Elderly are often not included in clinical trials evaluating efficacy and safety of study drugs for the treatment of inflammatory bowel diseases. Several drugs, such as aminosalicylates, systemic corticosteroids, immunosuppressant drugs, biological drugs and Janus Kinase inhibitors, are available for the management of inflammatory bowel diseases. With the increasing spectrum of therapeutic options, it is th…
Sociocultural Animation in Action: Reflections of a Practitioner From the Perspective of a Quarter of a Century
2018
Artykuł omawia cywilizacyjny kontekst powstania animacji społeczno--kulturalnej i jej dawne uwarunkowania, wskazując na rozwój jej zadań i funkcji. Animacja to dziejąca się zmiana w grupach i społecznościach lokalnych, będąca nerwem demokracji i społeczeństwa obywatelskiego. Artykuł kończy uzasadnienie jej potrzeby w skomplikowanej sytuacji funkcjonowania człowieka w zglobalizowanym świecie.
Ainavas aspekti Zemgales līdzenuma pašvaldību plānošanas dokumentos
2019
Darba mērķis ir izvērtēt ainavas aspektus Zemgales līdzenuma pašvaldību telpiskās attīstības plānošanas dokumentos. Izmantojot kvalitatīvo kontentanalīzi, lai izprastu kādos kontekstos ainava tiek aplūkota novadu pašvaldību dokumentos – ilgtspējīgās attīstības stratēģija, attīstības un teritoriju plānojumos. Apkopot kādas ainavas vērtības ir atspoguļotas Zemgales līdzenuma teritoriju pašvaldību novadu dokumentos. Kā arī cik kvalitatīvi ievērojot, noteiktos reģionālos un nacionālos ainavu mērķus, savstarpēji ir pašvaldību plānošanas dokumenti.