Search results for "O-2"
showing 10 items of 854 documents
Crystal structures of pure 3-(4-bromo-2-chlorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one and contaminated with 3-(4-b…
2017
The side product of the cyclocondensation reaction between ethyl benzimidazole-2-carboxylate and the nitrile imine of the corresponding hydrazonyl chloride, C20H11BrClN5O, crystallized in two crystal forms. Form (1) is a co-crystal of the target compound (without any chlorine substituent) and a side product containing a Cl atom in position 2 of the bromophenyl group, C20H12BrN5O·0.143C20H11BrClN5O. (2) contains the pure side product. The slightly different conformation of the ring systems leads to a different packing of (1) and (2), but both crystal structures are dominated by p-p interactions.
Transepithelial transport of betalainic phytochemicals in Caco-2 cell monolayers.
2010
Effect of caseinophosphopeptides added to fruit beverages upon ferritin synthesis in Caco-2 cells
2010
Ferritin synthesis was evaluated in iron sulphate solutions and in fruit beverages supplemented with iron, with/without zinc in the presence of caseinophosphopeptides (CPPs), based on a system combining simulated gastrointestinal digestion and the Caco-2 cell model. In iron sulphate solutions with/without zinc, the addition of CPPs had no effect upon ferritin synthesis. When CPPs were added to the bioaccessible fraction of fruit beverages supplemented with iron, ferritin synthesis increased in the same proportion as with the addition of milk. The addition of zinc to fruit beverages supplemented with iron and to iron sulphate solutions decreased ferritin synthesis. Nevertheless, in fruit bev…
Ferritin synthesis by Caco-2 cells as an indicator of iron bioavailability: Application to milk-based infant formulas
2007
The bioavailability of iron from milk-based infant formulas was estimated by an in vitro system including enzymatic digestion, iron uptake by Caco-2 cells and ferritin determination via an enzymoimmunoassay (ELISA). Positive correlations (p < 0.01) were found between the Fe(II) added to Caco-2 cells and ferritin synthesis and between the amount of dialyzed iron added to the cell culture and ferritin synthesis. The comparison of the bioavailability of iron from different milk-based formulas showed that adapted formulas having the same composition but differing in the iron salts added yielded similar ferritin levels. The same happened with follow-up formulas differing only in the presence or …
Iron and zinc bioavailability in Caco-2 cells: Influence of caseinophosphopeptides
2013
Abstract A study has been made of the influence of two pools of caseinophosphopeptides (CPPs) obtained from α s - and β-casein (CN) fractions, and of three specific CPPs (β-CN(1–25)4P, α s1 -CN(64–74)4P and α s2 -CN(1–19)4P), on iron bioavailability (ferritin synthesis) and zinc bioavailability (retention, transport and uptake of zinc) in Caco-2 cells. α-CPP and β-CPP pools did not improve ferritin synthesis, but the three specific CPPs showed an increase in ferritin synthesis in Caco-2 cells versus iron sulphate, β-CN(1–25)4P being the most effective. In relation to zinc bioavailability, α-CPPs, β-CPPs, α s1 -CN(64–74)4P and β-CN(1–25)4P increased zinc uptake. However, this increase was of…
Kinetic Characterization of Secretory Transport of a New Ciprofloxacin Derivative (CNV97100) across Caco-2 Cell Monolayers**This work has been submit…
2002
The kinetics of transport of a new fluoroquinolone antibiotic (CNV97100) and its analogs were characterized using the Caco-2 cell culture model. Unidirectional permeabilities of these analogs were greater (p < 0.05) than that of ciprofloxacin. The absorptive permeabilities (P(AB)) of 4'-N-substituted analogs (CNV97101-104) were 400-600% greater, whereas the secretory permeability (P(BA)) was 25-80% greater than unsubstituted analogs because CNV97101-104 were poor substrates for efflux transporters (efflux ratio approximately 1). The transport of compounds without 4'-N-substitution (i.e., ciprofloxacin and CNV97100) favored secretion (efflux ratio approximately 4). Further characterization o…
CCDC 1059034: Experimental Crystal Structure Determination
2015
Related Article: Z. Setifi, A. Valkonen, M.A. Fernandes, S. Nummelin, H. Boughzala, F. Setifi, C. Glidewell|2015|Acta Crystallogr.,Sect.E:Cryst.Commun.|71|509|doi:10.1107/S2056989015007306
CCDC 822778: Experimental Crystal Structure Determination
2012
Related Article: F.Kessler, R.D.Costa, D.D.Censo, R.Scopelliti, E.Orti, H.J.Bolink, S.Meier, W.Sarfert, M.Gratzel, Md.K.Nazeeruddin, E.Baranoff|2012|Dalton Trans.|41|180|doi:10.1039/c1dt10698h
CCDC 909181: Experimental Crystal Structure Determination
2013
Related Article: T.R.Barman,M.Sutradhar,M.G.B.Drew,E.Rentschler|2013|Polyhedron|51|192|doi:10.1016/j.poly.2013.01.001
CCDC 1562675: Experimental Crystal Structure Determination
2017
Related Article: György Szalóki, Vincent Croué, Vincent Carré, Frédéric Aubriet, Olivier Alévêque, Eric Levillain, Magali Allain, Juan Aragó, Enrique Ortí, Sébastien Goeb, Marc Sallé|2017|Angew.Chem.,Int.Ed.|56|16272|doi:10.1002/anie.201709483