Search results for "O-2"
showing 10 items of 854 documents
CCDC 170383: Experimental Crystal Structure Determination
2002
Related Article: G.Haufe, T.C.Rosen, O.G.J.Meyer, R.Frohlich, K.Rissanen|2002|J.Fluorine Chem.|114|189|doi:10.1016/S0022-1139(02)00040-4
CCDC 713165: Experimental Crystal Structure Determination
2009
Related Article: Francisco Estevan, Pipsa Hirva, Mercedes Sanaú, MaAngeles Úbeda|2018|Organometallics|37|2980|doi:10.1021/acs.organomet.8b00342
Estudio de la modificación en la absorción de fármacos en giardiasis y nuevas estrategias de formulación
2016
Giardia intestinalis es el agente causal de la giardiasis, una de las patologías intestinales más comunes en todo el mundo, cuya sintomatología principal es diarrea y malabsorción. La OMS indica que la prevalencia mundial es de 200 millones de individuos afectando especialmente a niños entre 2 y 12 años, los cuales son en su mayoría asintomáticos. Diversos estudios demuestran que existe un riesgo importante en la población infantil, pues la carencia de vitaminas y otros nutrientes que provoca esta parasitosis puede ocasionar graves desórdenes, como anemia, retraso del crecimiento y discapacidad intelectual. Aunque el efecto de Giardia sobre la absorción de nutrientes y vitaminas se ha estud…
Availability of iron from milk-based formulas and fruit juices containing milk and cereals estimated by in vitro methods (solubility, dialysability) …
2007
Abstract Iron solubility, dialysability and transport and uptake (retention + transport) by Caco-2 cells as indicators of iron availability have been estimated in the in vitro gastrointestinal digests of infant foods (adapted, follow-up and toddler milk-based formulas and fruit juices containing milk and cereals (FMC)). Low correlation coefficients (in all cases R -squared ⩽ 37.1%) were obtained between iron solubility or dialysability versus transport or uptake efficiency – a fact emphasizing the importance of incorporating Caco-2 cell cultures to in vitro systems in order to adapt the conditions to those found in in vivo assays. The highest uptake efficiency corresponded to FMC (25.6–26.1…
Antioxidant effect of casein phosphopeptides compared with fruit beverages supplemented with skimmed milk against H2O2-induced oxidative stress in Ca…
2008
Abstract Casein phosphopeptides (CPPs) have been proposed as potential dietary antioxidants on designing new functional products. A fruit beverage, with/without milk, was subjected to in vitro digestion. Caco-2 cultures were preincubated with soluble fractions or isolated CPPs, the latter obtained from skimmed milk. The mitochondrial activities (MTT test), intracellular GSH and GSH-reductase activity (GSH-Rd), cell cycle analysis and RNA distribution in cycle phases were studied after inducing oxidative stress status (5 mM H2O2). MTT conversion was better preserved by soluble fractions of fruit beverages, either with or without milk. GSH concentration was equally decreased, and GSH-Rd was i…
In vitro evaluation of glycol chitosan based formulations as oral delivery systems for efflux pump inhibition.
2017
Recently, we have reported that glycol chitosan (GCS) was able to reverse the P- glycoprotein (P-gp) efflux pump. The objective of the present study was to evaluate the potential of two GCS-based dosage forms (aqueous solution or nanoparticle suspension) for oral administration of the P-gp substrate Rho-123. A further aim of the present study was to assess the effect of the glycol chitosan-4-thiobutylamidine thiomer (GCS-TBA) on P-gp activity considering that the corresponding thiomer of chitosan series is a well-known P-gp inhibitor. Pre-treatment of Caco-2 cell monolayer with a GCS solution or GCS-based nanoparticles increased the absorptive transport of Rho-123 across the monolayer of 1.…
CCDC 984448: Experimental Crystal Structure Determination
2014
Related Article: Santos Fustero, Javier Miró, María Sánchez-Roselló, Carlos del Pozo|2014|Chem.-Eur.J.|20|14126|doi:10.1002/chem.201403340
CCDC 178473: Experimental Crystal Structure Determination
2002
Related Article: M.Horacek, P.Stepnicka, S.Gentil, K.Fejfarova, J.Kubista, N.Pirio, P.Meunier, F.Gallou, L.A.Paquette, K.Mach|2002|J.Organomet.Chem.|656|81|doi:10.1016/S0022-328X(02)01562-0
Effect of processing and food matrix on calcium and phosphorous bioavailability from milk-based fruit beverages in Caco-2 cells
2011
9 páginas, 4 figuras, 4 tablas.-- et al.
Iron Bioavailability in Fortified Fruit Beverages Using Ferritin Synthesis by Caco-2 Cells
2008
The bioavailability of iron from fortified fruit beverages was estimated by an in vitro system including enzymatic digestion, iron uptake by Caco-2 cells, and ferritin formation determined via an enzyme immunoassay (ELISA). Thus, the aim of the present study was to assess iron bioavailability as influenced by the presence of known dietary promoter and inhibitory factors in fortified fruit beverages containing iron and/or zinc and/or skimmed milk. No negative effect (p > 0.05) derived from micronutrient interaction can be ascribed to zinc supplementation on iron availability. Besides, the presence of caseinophosphopeptides derived from casein hydrolysis during digestion may confer enhancing …