Search results for "OBESITY"
showing 10 items of 1833 documents
Influence of metabolic syndrome on hypertension-related target organ damage
2005
MuleG, Nardi E, Cottone S, Cusimano P, Volpe V, Piazza G, MongioviR, Mezzatesta G, Andronico G, Cerasola G (Universitadi Palermo, Palermo, Italy). Influence of metabolic syndrome on hypertension-related target organ damage. J Intern Med 2005; 257: 503-513. Objectives. The aim of our study was to analyse, in a wide group of essential hypertensive patients without diabetes mellitus, the influence of metabolic syndrome (MS) (defined according to the criteria laid down in the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults) on markers of preclinical cardiac, renal and retinal damage. Design. Cros…
Basal metabolic rate in narcoleptic patients.
2009
PATIENTS SUFFERING FROM NARCOLEPSY TEND TO BE OBESE.1,2 AMONG OTHER HYPOTHESES LOWER RESTING ENERGY EXPENDITURE HAS BEEN SUSPECTED to be the cause of the narcolepsy-associated obesity.3,4 The use of indirect calorimetry is a well-established noninvasive method to measure the energy expenditure (EE) and the resting (basal) metabolic rate (BMR). Chabas et al. recently published an evaluation of eating behavior and energy balance of 7 typical and 6 atypical narcoleptic patients and 9 controls using indirect calorimetry. Narcoleptic patients were found to have a lower energy expenditure (EE) than controls (n = 13, P = 0.07). Thus, it was concluded that narcolepsy associated obesity could be the…
Influences of obesity and weight loss on thyroid hormones. A 3-3.5-year follow-up study on obese subjects with surgical bilio-pancreatic by-pass
1997
The effects of changing body size, energy intake and substrate oxidation on serum T4, FT4, T3, FT3 and TSH were investigated in ten morbidly obese subjects (4 men/6 women; age: 37 ± 6 years; BMI: 53.8 ± 6.5 kg/m2; mean ± SD) who had undergone a surgical bilio-pancreatic by-pass in order to reduce their body weight. The starting value of serum FT3 was inversely related to the BMI (r = -0.63; p < 0.05). After 1-3 months, all the subjects were losing weight and their intake of carbohydrates was almost negligible; at this time a significant reduction of T3 (-14.6%, p < 0.0001), T4 (-19.5%, p < 0.0001), and FT3 (-10.5%, p < 0.001) was observed. Nine to 16 months after surgery, all th…
A low resting metabolic rate is associated with metabolic syndrome
2007
Background & aims: The metabolic syndrome is associated with central accumulation of fat. Previous studies showed that some obese subjects are characterized by a sparing energy metabolism. The aim of this study was to investigate whether obese subjects with metabolic syndrome have a lower resting metabolic rate than obese subjects without metabolic syndrome. Methods: Forty obese subjects were divided into three groups according to the presence of metabolic syndrome and type 2 diabetes; 15 non-obese healthy control subjects were also enrolled. Body composition (bio-impedance analysis) and resting metabolic rate (indirect calorimetry) were performed. Results: The group with metabolic syndrome…
Association of Serum Retinol Binding Protein 4 with Atherogenic Dyslipidemia in Morbid Obese Patients
2013
Retinol binding protein 4 (RBP4) is an adipokine that may contribute to the development of insulin resistance. However, how this adipokine is affected and its possible involvement in lipid metabolism in obese patients with varying degrees of insulin resistance is yet to be determined. A total of 299 middle-aged morbid obese patients (BMI>40 kg/m(2)) were divided in euglycemic, metabolic syndrome or type 2 diabetic. Anthropometric measurements, biochemical variables and systemic RBP4 levels were determined. RBP4 levels were significantly higher in patients with metabolic syndrome and type 2 diabetes than in euglycemic subjects (42.9±14.6; 42.3±17.0 and 37.4±11.7 µg/ml, respectively) and corr…
Endothelial function and other biomarkers of cardiovascular risk in frequent consumers of street food.
2012
Summary Background & aims Street food (SF) is defined as out-of-home food consumption, and generally consists of energy dense meals rich in saturated fats, and poor in fibers, vitamins and anti-oxidants. Though SF consumption may have unfavorable metabolic and cardiovascular effects, its possible association with endothelial function has not been considered. Methods Participants were recruited among those who took part in a previous study of ours, done in Palermo, Italy, which investigated the association between consumption of SF and health in 1002 people. In that study, a score of SF consumption was obtained by categorizing each of ten foods consumed less than or more than once a month (0…
Waist circumference and BMI are independently associated with the variation of cardio-respiratory and neuromuscular fitness in young adult men.
2006
To test two hypotheses: (1) cardiorespiratory (CRF) and neuromuscular (NMF) fitness is associated with body mass index (BMI) and waist circumference (WC), independent of each other and of leisure-time physical activity; (2) individuals with high CRF and NMF have lower WC for a given BMI, compared with those with low CRF and NMF. Cross-sectional study. Men participating in refresher training organized by the Finnish Defence Forces. A total of 951 men (mean age 29.1, s.d. 4.2 years; BMI 25.3 kg/m2, s.d. 3.8; WC 91, s.d. 11 cm). Body mass index, WC, maximal oxygen uptake (VO2max), height of vertical jump, number of push-ups and sit-ups during a 1-min test, static back extension endurance, isom…
The role of obesity and physical activity in non-specific and radiating low back pain: The Young Finns study
2013
Objective To study the effects of obesity, physical activity, and change in physical activity on the incidence of low back pain and explore whether obesity modifies the effects of physical activity. Methods As part of the ongoing Young Finns Study, 1224 subjects aged 24–39 years free from low back pain during the preceding 12 months at baseline in 2001 were included. Obesity was defined based on the body mass index (BMI) and waist circumference, and physical activity was assessed by the metabolic equivalent of task (MET) index in 2001 and 2007. Results Abdominal obesity, defined by an increased waist circumference, was associated with an increased incidence of radiating low back pain (adjus…
Erythrocyte deformability in morbid obesity before bariatric surgery. Influence of abdominal obesity.
2010
Although there are several studies dealing with erythrocyte deformability (ED) in obese patients, research on this topic in morbidly obese subjects is scarce. In these studies ED seems to be decreased, although the cause remains unknown. A case-control study in 76 morbid obese subjects (23 women and 53 men, aged 44 ± 13 years) and in 79 normal-weight controls (30 women and 49 men, aged 43 ± 13 years) was undertaken. ED has been determined by ektacytometric techniques in a Rheodyn SSD, by means of the elongation index (EI) at 12, 30 and 60 Pascals, along with anthropometric, lipidic, metabolic and inflammatory parameters. EI was statistically lower in morbidly obese subjects than in controls…
Are abdominal obesity and body mass index independent predictors of hemorheological parameters?
2012
There is an association between obesity and rheological blood behavior [2, 4–7]. In this sense we have read with interest the recently published article by Brun et al. [1] in this journal. The authors evaluate, in a population of 430 subjects, the relationship between abdominal obesity and body mass index (BMI) with blood viscosity, and conclude that both anthropometric parameters are associated with increased blood viscosity but by different mechanisms, where the waist to hip ratio is a better predictor for blood viscosity than BMI. It is striking that in this study the authors do not indicate the variables included in the stepwise multivariate regression model, where plasma lipids, glucos…