Search results for "ODR"

Families of ICIS with constant total Milnor number

2021

We show that a family of isolated complete intersection singularities (ICIS) with constant total Milnor number has no coalescence of singularities. This extends a well-known result of Gabriélov, Lazzeri and Lê for hypersurfaces. We use A’Campo’s theorem to see that the Lefschetz number of the generic monodromy of the ICIS is zero when the ICIS is singular. We give a pair applications for families of functions on ICIS which extend also some known results for functions on a smooth variety.

On the irreducibility of Hurwitz spaces of coverings with two special fibers

2012

Corrigendum to “The monodromy groups of Dolgachev's CY moduli spaces are Zariski dense” [Adv. Math. 272 (2015) 699–742]

2015

Frobenius polynomials for Calabi–Yau equations

2008

We describe a variation of Dwork’ s unit-root method to determine the degree 4 Frobenius polynomial for members of a 1-modulus Calabi–Yau family over P1 in terms of the holomorphic period near a point of maximal unipotent monodromy. The method is illustrated on a couple of examples from the list [3]. For singular points, we find that the Frobenius polynomial splits in a product of two linear factors and a quadratic part 1− apT + p3T 2. We identify weight 4 modular forms which reproduce the ap as Fourier coefficients.

Irreducibility of Hurwitz spaces of coverings with one special fiber and monodromy group a Weyl group of type D d

2007

Let Y be a smooth, connected, projective complex curve. In this paper, we study the Hurwitz spaces which parameterize branched coverings of Y whose monodromy group is a Weyl group of type D d and whose local monodromies are all reflections except one. We prove the irreducibility of these spaces when $$Y \simeq \mathbb {P}^{1}$$ and successively we extend the result to curves of genus g ≥  1.

Synthesis and preliminary biological evaluation of a new pyridocarbazole derivative covalently linked to a thymidine nucleoside as a potential target…

2003

The therapy of human cancer is one of the more pursued goals by medicinal chemistry research. Most of the compounds clinically used as a treatment owe their efficacy to their cytotoxic interaction (direct or indirect) with nuclear DNA. This interaction results in the inhibition of DNA synthesis and the degradation of nucleic strands. Ellipticine is a naturally occurring 6H-pyrido[4,3-b]carbazole alkaloid endowed with antitumor activity, and several ellipticine derivatives have been used in clinical trials. We previously reported some 1,4-dimethyl-9H-carbazole derivatives structurally related to ellipticine. The purpose of our research was to transform the pyridocarbazole in a prodrug so tha…

Pārtikas nodrošinājuma tiesiskais regulējums Eiropas Savienībā

2015

Bekmane I.,2015. Pārtikas nodrošinājuma tiesiskais regulējums Eiropas Savienībā. Bakalaura darbs. Rīga, Latvijas Universitāte. 43 lpp. Šī darba mērķis ir analizēt pārtikas nodrošinājuma jēdziena saturu, problemātiku un izpētīt to, kādam tiesiskajam regulējumam ir pakļauts šis jēdziens Eiropas Savienībā. Autore secina, ka Eiropas Savienībā nepastāv vienots pārtikas nodrošinājuma regulējums un praksē tiek kļūdaini izprasts šī jēdziena saturs. Eiropas Savienībā ir nepieciešams veidot vienotu regulējumu sistēmu un instrumentus, kas veidotu pārtikas nodrošinājuma regulējumu un ar kuru palīdzību dalībvalstīm tiktu piemērotas sankcijas par attiecīgā regulējuma pārkāpumiem. Atslēgas vārdi: Pārtikas…

Theoretical study of a hydration mechanism in an enaminone pro-drug prototype

2003

Enaminones may act as pro-drugs releasing via proton-catalyzed hydrolysis a primary amine, which may be an actual drug. A hydration mechanism of prototype enaminone (2-propenal-3-amine) has been subjected to quantum chemical studies. All involved compounds were investigated in a search for the most likely reactive form. Results revealed that the proposed reaction pathway is thermodynamically possible.

RODRÍGUEZ ESTEBAN, María Ascensión. "La arquitectura de ladrillo y su construcción en la ciudad de Zamora (1888-1931)"

2016

Humanismo, soberanía y religión. Rafael Rodríguez de Cepeda (1850-1918), un catedrático de Valencia conservador

2008

Las grandes cuestiones políticas y jurídicas sobre el individuo y el Estado se debatieron en España durante el siglo x1x, entre quienes deseaban una profunda transformación y quienes mantenían posiciones conservadoras. El pensamiento conservador, aunque con cierta puesta al día, siguió aferrado a la defensa del altar y el trono: la religión y el absolutismo... Unos más que otros, los conservadores añoraban viejos tiempos y se mostraban contrarios a las novedades liberales. El jurista Rafael Rodríguez de Cepeda, desde la filosofía del derecho, es buen ejemplo de esa pervivencia de viejas ideas, que divide España a fines de aquel siglo en dos bloques de pensamiento diversos, contrapuestos.