Search results for "ODS"

showing 10 items of 5812 documents

The Large Area Detector onboard the eXTP mission

2018

The eXTP (enhanced X-ray Timing and Polarimetry) mission is a major project of the Chinese Academy of Sciences (CAS) and China National Space Administration (CNSA) currently performing an extended phase A study and proposed for a launch by 2025 in a low-earth orbit. The eXTP scientific payload envisages a suite of instruments (Spectroscopy Focusing Array, Polarimetry Focusing Array, Large Area Detector and Wide Field Monitor) offering unprecedented simultaneous wide-band X-ray spectral, timing and polarimetry sensitivity. A large European consortium is contributing to the eXTP study and it is expected to provide key hardware elements, including a Large Area Detector (LAD). The LAD instrumen…

Silicon detectorX-ray AstronomyComputer sciencecapillary platePolarimetryFOS: Physical sciencesField of viewContext (language use)Condensed Matter Physic01 natural sciencesSettore FIS/05 - Astronomia E Astrofisica0103 physical sciencesElectroniccapillary plates; Silicon detectors; Timing; X-ray Astronomy; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications1707 Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringTimingOptical and Magnetic MaterialsAerospace engineeringSpectral resolutionElectrical and Electronic Engineering010306 general physicscapillary plates; Silicon detectors; Timing; X-ray Astronomy; astro-ph.IM; astro-ph.IM; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications1707 Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringInstrumentation and Methods for Astrophysics (astro-ph.IM)X-ray astronomycapillary plates010308 nuclear & particles physicsbusiness.industryPayloadElectronic Optical and Magnetic MaterialApplied MathematicsDetectorAntenna apertureComputer Science Applications1707 Computer Vision and Pattern RecognitionCondensed Matter PhysicsApplied MathematicSilicon detectorsAstrophysics - Instrumentation and Methods for Astrophysicsbusinessastro-ph.IM
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Structure and diffusion of oxygen and silicon interstitials in silicon

1999

Abstract Ab initio quantum chemical simulation of silicon interstitials and oxygen-related defects Oi, V–O2, and V–O4 in oxygen-containing silicon was performed using the embedded molecular cluster model. The defect geometry and electronic structure were studied. The migration activation energy for Oi defect was estimated as 2.73 eV at the atmospheric pressure, and 2.70, 2.68, and 1.92 eV for the lattice compressed by 0.25, 0.37, or 5.0 per cent, respectively. The activation energy of silicon interstitial is not changing with pressure. The molecular cluster used to simulate V–O4 defect with C2v symmetry was shown to have only slight deviation from D2d at atmospheric pressure, a strong devia…

SiliconAtmospheric pressureMechanical EngineeringMetals and AlloysAb initioNucleationchemistry.chemical_elementActivation energyElectronic structureCrystallographic defectMolecular physicsCrystallographychemistryMechanics of MaterialsAb initio quantum chemistry methodsMaterials ChemistryJournal of Alloys and Compounds
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Baseline design of the filters for the LAD detector on board LOFT

2014

The Large Observatory for X-ray Timing (LOFT) was one of the M3 missions selected for the phase A study in the ESA's Cosmic Vision program. LOFT is designed to perform high-time-resolution X-ray observations of black holes and neutron stars. The main instrument on the LOFT payload is the Large Area Detector (LAD), a collimated experiment with a nominal effective area of ~10 m 2 @ 8 keV, and a spectral resolution of ~240 eV in the energy band 2-30 keV. These performances are achieved covering a large collecting area with more than 2000 large-area Silicon Drift Detectors (SDDs) each one coupled to a collimator based on lead-glass micro-channel plates. In order to reduce the thermal load onto …

SiliconCosmic VisionPhysics - Instrumentation and DetectorsSpectral resolutionSilicon drift detectorVisionAstrophysics::High Energy Astrophysical PhenomenaCollimatorsObservatoriesFOS: Physical sciencesCollimated lightlaw.inventionSettore FIS/05 - Astronomia E AstrofisicaOpticsObservatorylawX-raysSpectral resolutionphysics.ins-detInstrumentation and Methods for Astrophysics (astro-ph.IM)PhysicsEquipment and servicesLead glassSensorsbusiness.industryDetectorAntenna apertureAstrophysics::Instrumentation and Methods for AstrophysicsCollimatorInstrumentation and Detectors (physics.ins-det)Microchannel platesbusinessAstrophysics - Instrumentation and Methods for Astrophysicsastro-ph.IM
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Theory of the growth mode for a thin metallic film on an insulating substrate

2002

We have developed a novel theory predicting the growth mode of a thin metallic film on an insulating substrate. This combines ab initio electronic structure calculations for several ordered metal/insulator interfaces (varying both coverage and substrate lattice constant), with a thermodynamic approach based on microscopic calculations. We illustrate this approach for Ag film deposited on MgO(0 0 1) substrate. Ab initio calculations predict high mobility of adsorbed silver atoms on the perfect magnesia surface even at low temperatures. Our theoretical analysis clearly demonstrates that the growth of metallic islands is predominant at the initial stage of silver deposition, which agrees with …

SilverCondensed matter physicsChemistryThermodynamic equilibriumAb initio quantum chemical methods and calculationsAb initioEquilibrium thermodynamics and statistical mechanicsCrystal growthSurfaces and InterfacesElectronic structureGrowthCondensed Matter PhysicsSurfaces Coatings and FilmsMetalCondensed Matter::Materials ScienceLattice constantTransition metalAb initio quantum chemistry methodsCoatingsvisual_artMaterials Chemistryvisual_art.visual_art_mediumPhysics::Atomic and Molecular ClustersPhysical chemistryMagnesium oxidesSurface Science
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Microfluidic continuous flow synthesis of rod-shaped gold and silver nanocrystals

2009

We present a continuous flow synthesis of gold and silver nanorods allowing tailored design of particles with desired shapes and online monitoring of particle growth.

SilverMaterials sciencemedicine.diagnostic_testContinuous flowMicrofluidicsMetal NanoparticlesGeneral Physics and AstronomyNanotechnologySolutionsTransition metalNanocrystalSpectrophotometrySpectrophotometryParticle growthmedicineParticleGoldPhysical and Theoretical ChemistrySilver nanorodsPhys. Chem. Chem. Phys.
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Incidence of DAA failure and the clinical impact of retreatment in real-life patients treated in the advanced stage of liver disease: Interim evaluat…

2017

Background: Few data are available on the virological and clinical outcomes of advanced liver disease patients retreated after first-line DAA failure. Aim: To evaluate DAA failure incidence and the retreatment clinical impact in patients treated in the advanced liver disease stage. Methods: Data on HCV genotype, liver disease severity, and first and second line DAA regimens were prospectively collected in consecutive patients who reached the 12-week post-treatment and retreatment evaluations from January 2015 to December 2016 in 23 of the PITER network centers. Results: Among 3,830 patients with advanced fibrosis (F3) or cirrhosis, 139 (3.6%) failed to achieve SVR. Genotype 3, bilirubin lev…

SimeprevirMaleGenetics and Molecular Biology (all)HepacivirusPediatricsGastroenterologyBiochemistry0302 clinical medicineAnimal Cells80 and overBileMedicinePublic and Occupational HealthProspective Studieslcsh:ScienceAged 80 and overAdult; Aged; Aged 80 and over; Antiviral Agents; Drug Therapy Combination; Female; Hepatitis C; Humans; Incidence; Liver Diseases; Male; Middle Aged; Prospective Studies; Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Liver DiseaseIncidenceLiver DiseasesChild HealthBloodCirrhosisPhysical SciencesRegression Analysis030211 gastroenterology & hepatologyDrug Therapy CombinationCellular TypesStatistics (Mathematics)Humanmedicine.medical_specialtyGastroenterology and HepatologyMicrobiologyAntiviral Agents03 medical and health sciencesDrug TherapyHumansStatistical MethodsAgedBlood CellsBiochemistry Genetics and Molecular Biology (all)Flaviviruseslcsh:ROrganismsBiology and Life Sciencesmedicine.diseaseRegimenProspective Studie030104 developmental biologychemistryAgricultural and Biological Sciences (all)lcsh:QMathematicsDevelopmental BiologyRNA viruses0301 basic medicineDAA HCV resistanceSofosbuvirPhysiologylcsh:MedicineLiver diseasechemistry.chemical_compoundMathematical and Statistical TechniquesMedicine and Health SciencesPathology and laboratory medicineMultidisciplinaryHepatitis C virusHepatitis CMedical microbiologyMiddle AgedHepatitis CBody FluidsVirusesCombinationFemaleAnatomyPathogensResearch Articlemedicine.drugPlateletsLedipasvirAdultDaclatasvirSettore MED/12 - GASTROENTEROLOGIAHCV liver diseases Cirrhosis DAA failureResearch and Analysis MethodsInternal medicineAntiviral Agentbusiness.industryViral pathogensBilirubinCell BiologyFibrosisHepatitis virusesMicrobial pathogensSurgeryLiver functionbusiness
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Efficacy of a 12-Week Simeprevir Plus Peginterferon/Ribavirin (PR) Regimen in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 4 (GT4) …

2017

Background HCV GT4 accounts for up to 20% of HCV infections worldwide. Simeprevir, given for 12 weeks as part of a 24- or 48-week combination regimen with PR is approved for the treatment of chronic HCV GT4 infection. Primary study objectives were assessment of efficacy and safety of simeprevir plus PR in treatment-naïve patients with HCV GT4 treated for 12 weeks. Primary efficacy outcome was sustained virologic response 12 weeks post-treatment (SVR12). Additional objectives included investigation of potential associations of rapid virologic response and baseline factors with SVR12. Methods This multicentre, open-label, single-arm study (NCT01846832) evaluated efficacy and safety of simepre…

SimeprevirMalePsychologie appliquéeFetge - MalaltiesHepacivirusGastroenterologyPolyethylene GlycolPolyethylene Glycols0302 clinical medicinelcsh:Science61 - MedicinaLiver DiseasesSciences bio-médicales et agricolesCirrhosisInterferonLiver Fibrosis030211 gastroenterology & hepatologyDrug Therapy CombinationViral loadBiologieHumanmedicine.medical_specialtyCiències multidisciplinàriesGenotypeSaudi ArabiaAlpha interferon:Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]Gastroenterology and HepatologyMicrobiologyAntiviral Agents03 medical and health sciencesHumansAgedMedicine and health sciencesHepaciviruFlavivirusesInterleukinslcsh:ROrganismsInterleukinmedicine.diseaseRegimen:Digestive System Diseases::Liver Diseases [DISEASES]chemistryImmunologylcsh:QMedicaments - AdministracióDevelopmental BiologyRNA viruseslcsh:Medicinemedicine.disease_cause:Other subheadings::Other subheadings::/drug therapy [Other subheadings]Geographical Locationschemistry.chemical_compoundSimeprevirHospital Universitari Vall d’Hebron030212 general & internal medicinePathology and laboratory medicineMultidisciplinaryHepatitis C virusHepatitis CRecombinant ProteinMedical microbiologyMiddle AgedViral LoadHepatitis CRecombinant Proteins:enfermedades del sistema digestivo::enfermedades hepáticas [ENFERMEDADES]EuropeResearch DesignVirusesFemalePathogensResearch ArticleAdultAsiaAdolescentClinical Research DesignHepatitis C virusResearch and Analysis MethodsYoung AdultInternal medicineRibavirinmedicineddc:610Rapid Virologic ResponseAntiviral AgentBiology and life sciencesbusiness.industryRibavirinViral pathogensInterferon-alphaFibrosisHepatitis virusesMicrobial pathogensPeople and PlacesAdverse EventsInterferonsbusinessPLoS ONE
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Generalized singly-implicit Runge-Kutta methods with arbitrary knots

1985

The aim of this paper is to derive Butcher's generalization of singly-implicit methods without restrictions on the knots. Our analysis yields explicit computable expressions for the similarity transformations involved which allow the efficient implementation of the first phase of the method, i.e. the solution of the nonlinear equations. Furthermore, simple formulas for the second phase of the method, i.e. computation of the approximations at the next nodal point, are established. Finally, the matrix which governs the stability of the method is studied.

Similarity (geometry)Computer Networks and CommunicationsGeneralizationApplied MathematicsComputationMathematical analysisStability (learning theory)Computational MathematicsMatrix (mathematics)Runge–Kutta methodsNonlinear systemSimple (abstract algebra)SoftwareMathematicsBIT
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Site symmetry approach applied to the supercell model of MgAl2O4 spinel with oxygen interstitials: Ab initio calculations

2018

This study has been carried out within the framework of the EUROfusion Consortium and has been provided funding from the Euratom research and training programme 2014-2018 under grant agreement No 633053. The authors are indebted to E.A. Kotomin, A.I. Popov and R. Vila for stimulating discussions. The views and opinions expressed herein do not necessarily reflect those of the European Commission. Calculations have been performed using both the Marconi supercomputer system at the Computational Simulation Centre (Italy) and the Computer Center of St. Petersburg State University.

Single neutral oxygen interstitialMaterials scienceGeneral Computer ScienceBand gapSite symmetryGeneral Physics and Astronomy02 engineering and technologyengineering.material010402 general chemistry01 natural sciencesMolecular physicsPhysics::GeophysicsCrystalCondensed Matter::Materials ScienceLattice constantPerfect crystalAb initio quantum chemistry methods:NATURAL SCIENCES:Physics [Research Subject Categories]General Materials ScienceBulk modulusSpinelMgAl2O4 spinelGeneral Chemistry021001 nanoscience & nanotechnology0104 chemical sciencesComputational MathematicsMechanics of MaterialsengineeringWyckoff positions0210 nano-technologyFirst principles calculations
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Multidomain spectral method for the Gauss hypergeometric function

2018

International audience; We present a multidomain spectral approach for Fuchsian ordinary differential equations in the particular case of the hypergeometric equation. Our hybrid approach uses Frobenius’ method and Moebius transformations in the vicinity of each of the singular points of the hypergeometric equation, which leads to a natural decomposition of the real axis into domains. In each domain, solutions to the hypergeometric equation are constructed via the well-conditioned ultraspherical spectral method. The solutions are matched at the domain boundaries to lead to a solution which is analytic on the whole compactified real line R∪∞, except for the singular points and cuts of the Rie…

Singular differential equationsMathematics::Classical Analysis and ODEsRiemann sphere[MATH] Mathematics [math]010103 numerical & computational mathematics01 natural sciencessymbols.namesakeFOS: MathematicsHypergeometric functionMathematics - Numerical Analysis[MATH]Mathematics [math]0101 mathematicsHypergeometric functionQAMathematicsLaplace's equationApplied MathematicsRiemann surfaceMathematical analysisNumerical Analysis (math.NA)[MATH.MATH-NA] Mathematics [math]/Numerical Analysis [math.NA]Hypergeometric distribution010101 applied mathematicsSpectral methodsHarmonic functionOrdinary differential equationsymbolsSpectral method[MATH.MATH-NA]Mathematics [math]/Numerical Analysis [math.NA]Numerical Algorithms
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