Search results for "OFTALMOLOGÍA"
showing 10 items of 53 documents
Stereoacuity with simultaneous vision multifocal contact lenses.
2010
Our purpose was to evaluate near stereoacuity (SA) with Focus Progressives and PureVision Multifocal simultaneous vision contact lenses. In a cross-over study design, 20 presbyopic subjects were fitted with either the Focus Progressives or PureVision Multifocal lenses. After 1 month, SA was measured with the vectographic Titmus, Random dot stereotests, and the Howard-Dolman apparatus under photopic conditions (85 lux) at 40 cm. Binocular high-contrast visual acuity at distance and near was examined. Subjects were then refitted with the alternative correction and the procedure was repeated. Mean SA with the Focus Progressive was 21 +/- 7 sec arc, 54 +/- 17 sec arc, and 51 +/- 21 sec arc, wit…
Diagnostic accuracy of nonmydriatic fundus photography for the detection of glaucoma in diabetic patients.
2015
Purpose. To determine the diagnostic accuracy for glaucoma of a set of criteria with nonmydriatic monoscopic fundus photography (NMFP) in diabetics. Methods. Diabetics recruited from a screening program for diabetic retinopathy and diabetic glaucoma patients recruited from our glaucoma unit were included. Any patient with evidence of diabetic retinopathy was excluded. Diabetic patients had to have no visual field defects to be included as controls. Glaucoma patients had to have a glaucomatous field defect in at least one eye to be included. One NMFP was taken per eye for all subjects. These photographs were evaluated by two masked glaucoma specialists for the presence of the following: bila…
Análisis del tejido coroideo como factor pronóstico en pacientes con degeneración macular asociada a la edad neovascular tipo 1 en régimen de tratami…
2015
OBJETIVO: Evaluar la asociación entre el grosor coroideo subfoveal y el resultado funcional durante un régimen de tratamiento a demanda con ranibizumab intravítreo en ojos con lesiones de tipo 1 secundarias a degeneración macular asociada a la edad (DMAE) neovascular. DISEÑO: Estudio retrospectivo, longitudinal y transversal. MÉTODOS: Se incluyeron 25 ojos de 21 pacientes con evidencia clínica de lesiones de tipo 1 en el contexto de DMAE neovascular tratados con inyecciones intravítreas de 0.5mg de ranibizumab (Lucentis, Novartis) durante 24 meses de acuerdo con un régimen pro re nata (tratar y observar). Se registró la agudeza visual y el número de inyecciones administradas a lo largo del …
Alteraciones en glándulas de Meibomio y superficie ocular en pacientes con diabetes tipo 2
2018
Objetivo: Analizar el estado de las glándulas de Meibomio, superficie ocular y película lagrimal en pacientes con diabetes tipo 2. Metodología y Métodos: Estudio prospectivo de 142 ojos en 76 participantes, 37 con diabetes tipo 2 con un promedio de duración de la enfermedad de 5 años, y un grupo control con 36 participantes. Se evaluaron los síntomas con el cuestionario OSDI índice de enfermedad de superficie ocular, el tiempo de ruptura no invasivo de la película lagrimal (NIBUT) y el patrón interferencial de capa lipídica lagrimal se evaluaron mediante sistema de interferometría lagrimal (tearscope-polaris-bon®); se evaluó la altura de menisco lagrimal con la tomografía de coherencia ópti…
Metabolómica de la lágrima
2016
“Super p53” Mice Display Retinal Astroglial Changes
2013
Tumour-suppressor genes, such as the p53 gene, produce proteins that inhibit cell division under adverse conditions, as in the case of DNA damage, radiation, hypoxia, or oxidative stress (OS). The p53 gene can arrest proliferation and trigger death by apoptosis subsequent to several factors. In astrocytes, p53 promotes cell-cycle arrest and is involved in oxidative stress-mediated astrocyte cell death. Increasingly, astrocytic p53 is proving fundamental in orchestrating neurodegenerative disease pathogenesis. In terms of ocular disease, p53 may play a role in hypoxia due to ischaemia and may be involved in the retinal response to oxidative stress (OS). We studied the influence of the p53 ge…
Two-year retrospective analysis of the international impact of Journal of Optometry: part II
2011
The Journal of Optometry – Peer-reviewed Journal of the Spanish General Council of Optometrists- was launched in March 2008 publishing the first issue by September 2008. It is now reaching 2.5 years of activity in spreading clinical and scientific knowledge in the field of Optometry and Visual Science and related areas. Despite this short path within the international scientific publication scenario, it is appropriate to stop and reflect about the challenges, achievements and the numbers that are making J Optom a reference in this competitive area. In this editorial we will discuss the steps followed to setup the journal and the actual international impact in terms of audience from the read…
Cirugía no penetrante del glaucoma con espolonectomía. Valoración anatómica y funcional.
2016
INTRODUCCIÓN El glaucoma es una neuropatía óptica multifactorial que cursa con una pérdida progresiva de campo visual. La presión intraocular (PIO) es el factor de riesgo más importante y el parámetro modificable que mejor permite variar la evolución natural de la enfermedad. El tratamiento médico permite un control de la enfermedad en la mayoría de los casos, pero en ocasiones es necesario recurrir al tratamiento quirúrgico para producir descensos de la presión intraocular que eviten la progresión del daño. La trabeculectomía es el técnica quirúrgica de referencia, pero han ido apareciendo diferentes opciones con la finalidad de mantener los buenos resultados tensionales disminuyendo las c…
Changes in visual function and retinal structure in the progression of Alzheimer's disease
2019
Background Alzheimer's Disease (AD) can cause degeneration in the retina and optic nerve either directly, as a result of amyloid beta deposits, or secondarily, as a result of the degradation of the visual cortex. These effects raise the possibility that tracking ophthalmologic changes in the retina can be used to assess neurodegeneration in AD. This study aimed to detect retinal changes and associated functional changes in three groups of patients consisting of AD patients with mild disease, AD patients with moderate disease and healthy controls by using non-invasive psychophysical ophthalmological tests and optical coherence tomography (OCT). Methods We included 39 patients with mild AD, 2…
The Role of Autophagy in Eye Diseases
2021
Autophagy is a catabolic process that ensures homeostasis in the cells of our organism. It plays a crucial role in protecting eye cells against oxidative damage and external stress factors. Ocular pathologies of high incidence, such as age-related macular degeneration, cataracts, glaucoma, and diabetic retinopathy are of multifactorial origin and are associated with genetic, environmental factors, age, and oxidative stress, among others; the latter factor is one of the most influential in ocular diseases, directly affecting the processes of autophagy activity. Alteration of the normal functioning of autophagy processes can interrupt organelle turnover, leading to the accumulation of cellula…