Search results for "OHM"

Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

Multipore membranes with nanofluidic diodes allowing multifunctional rectification and logical responses

2016

[EN] We have arranged two multipore membranes with conical nanopores in a three-compartment electrochemical cell. The membranes act as tunable nanofluidic diodes whose functionality is entirely based on the pH-reversed ion current rectification and does not require specific surface functionalizations. This electrochemical arrangement can display different electrical behaviors (quasi-linear ohmic response and inward/outward rectifications) as a function of the electrolyte concentration in the external solutions and the applied voltage at the pore tips. The multifunctional response permits to implement different logical responses including NOR and INHIBIT functions.

Spatiotemporal colorimetry to reveal electrochemical kinetics of poly(o-toluidine) films along ITO surface

2018

Abstract Sheet resistance of transparent conducting electrodes can affect dramatically the electrochromic response of surface confined active species in any electrochromic device. The generated gradient of effective potential on the electrode surface has a direct impact on the electrochemical kinetics of these species. In this work, the electrochromic poly (o-toluidine) (POT) film, a derivative polyaniline, was deposited along a narrow, long transparent indium tin oxide (ITO) supporting electrode with a sheet resistivity of 30 Ω cm−1. This configuration was used as a model to simulate a surface electrical conduction from the external metallic contact to the opposite extreme of ITO with an i…

Electron structure, ultra-dense hydrogen and low energy nuclear reactions

2019

In this paper, a simple Zitterbewegung electron model, proposed in a previous work, is presented from a different perspective based on the principle of mass- frequency equivalence. A geometric- electromagnetic interpretation of mass, relativistic mass, De Broglie wavelength, Proca, Klein- Gordon, Dirac and Aharonov- Bohm equations in agreement with the model is proposed. A non-relativistic, Zitterbewegung interpretation of the 3.7 keV deep hydrogen level found by J. Naudts is presented. According to this perspective, ultra-dense hydrogen can be conceived as a coherent chain of bosonic electrons with protons or deuterons located in the center of their Zitterbewegung orbits. This approach sug…

2017

Dielectric loaded surface plasmon waveguides (DLSPPWs) comprised of polymer ridges deposited on top of CMOS compatible metal thin films are investigated at telecom wavelengths. We perform a direct comparison of the properties of copper (Cu), aluminum (Al), titanium nitride (TiN) and gold (Au) based waveguides by implementing the same plasmonic waveguiding configuration for each metal. The DLSPPWs are characterized by leakage radiation microscopy and a fiber-to-fiber configuration mimicking the cut-back method. We introduce the ohmic loss rate (OLR) to analyze quantitatively the properties of the CMOS metal based DLSPPWs relative to the corresponding Au based waveguides. We show that the Cu,…

METHOD FOR MANUFACTURING A UV-RADIATION DETECTOR DEVICE BASED ON SIC, AND UV-RADIATION DETECTOR DEVICE BASED ON SIC

2021

The quantum phase slip phenomenon in superconducting nanowires with a low-Ohmic environment

2012

In a number of recent experiments it has been demonstrated that in ultra-narrow superconducting channels quantum fluctuations of the order parameter, alternatively called quantum phase slips, are responsible for the finite resistance well below the critical temperature. The acceptable agreement between those experiments and the models describing quantum fluctuations in quasi-one-dimensional superconductors has been established. However the very concept of the phase slip is justified when these fluctuations are the relatively rare events, meaning that the effective resistance of the system should be much smaller than the normal state equivalent. In this paper we study the limit of the strong…

Ohmic drop of Prussian-blue/graphite+epoxy electrodes

1999

Abstract Ohmic drop effects on the voltammogram shape of the Prussian-blue⇌Everitt’s salt system have been studied by considering the electroactive film model. As the uncompensated resistance varies, the experimental characteristic curve parameters also varies. A dependence of the voltammograms with the graphite proportion was found related with the ohmic drop due to the composite electrodes. The optimal graphite proportion to obtain a good faradaic-to-charge current ratio was 62% in weight which coincides with the second percolation threshold. The ohmic overpotential, which relates the ohmic drop with the electrochemical magnitudes, is also minimum at this proportion.

Modeling and numerical simulation of the propagation of pitting corrosion of iron in chlorinated medium : contribution to the evaluation of the durab…

2012

This study deals with the understanding of the mechanisms of pitting corrosion susceptible to occur on carbon steel selected for high level nuclear waste containers. Transport/reaction models have been developed in order to simulate, by finite element method, the propagation of a pit on iron in chlorinated medium. For conservative models, pit is activated by imposing a potential on metal. Thanks to different parametric studies (geometry, environment…) simulations have permitted to classify, by severity order, the factors responsible of the increase or the inhibition of the localized corrosion rate. Otherwise, experiments on occluded (called « lead-in-pencil ») electrodes confirm that confin…

Direkte Dickenmessung an Muskelstreifenpräparaten und Gewebsschnitten

1967

An apparatus for direct measurement of the thickness of tissue slices and muscle strips is described. Micrometer callipers are used, the proper adjustment of which is indicated by the sudden scale deflection of an ohmmeter. In comparison with the method of calculation based on a measurement of the area of the slice, this technique is time-saving and the results are more accurate and reproducible.