Search results for "OLAP"

Slightly radiopaque uric acid calculi: impact upon therapeutic considerations?

1989

Ten patients with slightly radiopaque urinary calculi were treated by percutaneous litholapaxy or even open surgery. The stone analysis revealed uric acid as the main stone composite suggesting that these patients should have been treated by oral litholysis alone alkalinizing the urine and decreasing uric acid levels with allopurinol. CT density measurements proved that concrements with HE less than 600 can be successfully dissolved by oral medication alone. Twenty-four patients were subsequently treated by oral citrate alkalinizing the spontaneous urine to pH 6.8-7.2 dissolving even large staghorns within 6-8 weeks. CT density measurements have become a routine diagnostic procedure when po…

Solapamiento del nicho trófico en un área de cría en la costa portuguesa

2002

The diets and the trophic niche overlap between seven flatfish species were studied in a coastal nursery adjoining to the Tagus estuary (Portugal). Fish were sampled monthly, from March to November 1999, using a beach seine. Arnoglossus imperialis (Rafinesque, 1810), Arnoglossus laterna (Walbaum, 1792) and Arnoglossus thori Kyle, 1913, fed mainly on crustaceans. The diets of Buglossidium luteum (Risso, 1810) and Dicologoglossa cuneata (Moreau, 1881) were mainly composed of Bivalvia and Polychaeta, while for Scophthalmus rhombus (Linnaeus, 1758) the main food items were Mysidacea and Teleostei. The diet of Pegusa lascaris (Risso, 1810) was mainly composed by Cumacea, Bivalvia, Decapoda and A…

Diseases of the External Anal Area

1979

Diseases of the external anal area may be diagnosed during inspection using good lighting. Because of the variable responses to treatment, the individual diseases should be diagnostically distinguished from one another.

La transición entre turnos conversacionales : Silencios, solapamientos e interrupciones

1993

Beatriz.Gallardo@uv.es En este artículo se estudia la problemática de la transición entre turnos. Los silencios, los solapamientos y las interrupciones son los fenómenos más evidentes derivados de las unidades conversacio nales. Se analizan la clasificación y la tipología de estos elementos. El silencio puede clasificarse como pausa, intervalo o lapso, según la posición en la conversación. En los casos de habla simultánea se pueden dar solapamientos colaborativos o competitivos (interrupciones), con una gradación interna regulada por la organización conversacional.

Rad51 and BRCA2 - New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer Drugs

2011

First line chemotherapeutics for brain tumors (malignant gliomas) are alkylating agents such as temozolomide and nimustine. Despite growing knowledge of how these agents work, patients suffering from this malignancy still face a dismal prognosis. Alkylating agents target DNA, forming the killing lesion O(6)-alkylguanine, which is converted into DNA double-strand breaks (DSBs) that trigger apoptosis. Here we assessed whether inhibiting repair of DSBs by homologous recombination (HR) or non-homologous end joining (NHEJ) is a reasonable strategy for sensitizing glioma cells to alkylating agents. For down-regulation of HR in glioma cells, we used an interference RNA (iRNA) approach targeting Ra…

Corrigendum to "poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells" [Biochim. B…

2018

Fig. 1. The effects of the DHMEQ–Olaparib combination on HCC cells. (A) Cells were treated for 72 hwith the indicated concentrations of DHMEQ–Olaparib and cell viability was assessed by MTS assays. The DHMEQ–Olaparib combination showed synergistic inhibition of cell viability in Hep3B cells and additive inhibition in Huh7 cells. Combination index (CI) values are indicated above the bar. Data are expressed as percent cell growth and are the mean ± SD of three separate experiments (each of which was performed in triplicate). *p b 0.05 and **p b 0.01 versus each agent alone. (B) Cells were treated for 24 h with DHMEQ (μg/ml) or Olaparib (μM) alone or in combination, allowed to grow for 14 days…

Poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells

2014

Poly (ADP-ribose) polymerase (PARP) enzymes play a key role in the cellular machinery responsible for DNA repair. Dehydroxymethylepoxyquinomicin (DHMEQ), a new inhibitor of NF-κB, induces oxidative stress and DNA damage. The effects of DHMEQ in combination with Olaparib (PARP inhibitor) were studied on hepatocellular carcinoma (HCC) cells. The DHMEQ-Olaparib combination synergistically inhibited cell viability, cell proliferation and colony formation of Hep3B, but had additive effects on Huh7 cells. The synergistic effects of the combination correlated with increased apoptosis, caspase 3/7 activity and PARP cleavage. There was an induction of an endoplasmic reticulum (ER) stress response wi…

Poesias con que han adornado la fachada de su templo los PP. de la Escuela Pia con el plausible motivo de la venida de SS. MM. y AA. a Valencia.

Sign.: [ ]2, A-M2, N3

Afectos de un desapasionado al aver visto la insolente, e infamatoria Critica, que ha aparecido en este Correo, contra el celebre, y aplaudido Sermon…

Al final: "Su Autor, en puro anagrama. Danteo, Rachea, y Jesus" Sign.: [ ]2 Reclams

Darījumu inteliģences sistēma finanšu atskaitēm FINREP formātā

2017

Maģistra darbā ir izskatītas FINREP (Financial Reporting) finanšu datu atskaišu standarta pielāgošanas iespējas darījumu inteliģences sistēmām. FINREP standartu izstrādāja Eiropas Banku iestāde, to izmantošana ir reglamentēta Eiropas Savienības kredītiestādēm, kas atbilst noteiktām prasībām. Maģistra darba mērķis ir izpētīt FINREP finanšu atskaišu veidošanas iespējas Oracle Hyperion Financial Management maksas rīkā, kā arī izpētīt pieejamos atvērtā koda darījumu inteliģences risinājumus. Izvēloties vienu no atvērtā koda sistēmām, izpētīt to pielāgošanas iespējas FINREP atskaitēm, secinot vai ir iespējams panākt līdzīgo funkcionalitāti kā Oracle Hyperion rīkā.