Search results for "OLP"

Commento agli artt. 334, 335, 335 bis CP

2009

Influence of inorganic pyrophosphate on the kinetics of muscle pyruvate kinase: a simple nonallosteric feedback model.

2002

Potassium pyrophosphate was used instead of ATP as a model ligand for magnesium cation for the study of effector influence on the kinetics of pyruvate kinase muscle isozyme M1. The pyruvate kinase activation by low concentration of pyrophosphate and inhibition by high concentration of pyrophosphate was considered to be the result of reversible reactions of magnesium cation with pyrophosphate, ADP, ATP, and PEP. The apparent Km and Vm or in some cases the pseudo-first order reaction rate constant (instead of Km and Vm) of pyruvate kinase at any given pyrophosphate concentration were analysed as a function of concentration of free magnesium cation and its complexes with all ligands present in…

A hypothetical model of the influence of inorganic phosphate on the kinetics of pyruvate kinase

2000

This paper presents a simple solution to the problem of approximating the calculated curve of reaction progress to the measured curve which is usually disturbed by initial oscillation of auxiliary lactate dehydrogenase (LDH) reaction. The experiments leading to the determination of the apparent Km for phosphoenolpyruvate (PEP) and Vm were performed. For precise estimation of kinetic parameters (Km and Vm) of the M1 isozyme of pyruvate kinase (PK), measured by coupling it to LDH reaction, the sequence of Michaelis‐Menten for pyruvate kinase and second-order kinetics for lactate dehydrogenase reaction as well as a non-zero initial concentration of lactate was assumed. The functions of apparen…

Hydrogels for potential colon drug release by thiol-ene conjugate addition of a new inulin derivative.

2008

Inulin was chosen as a starting polymer for biocompatible, pH-sensitive and biodegradable hydrogels. Three INUDVSA-TT hydrogels were obtained by crosslinking inulin derivatives with trimethylolpropane tris(3-mercaptopropionate) under varying conditions. The resulting hydrogels were cell compatible, as demonstrated by MTS and trypan blue exclusion assays acting on Caco-2 cells, and were biodegraded by inulinase and esterase, thus suggesting their use as colonic drug delivery systems. 2-Methoxyestradiol, an anti-cancer drug, was soaked in INUDVSA-TT hydrogels and its in vitro release and apoptotic effect on Caco-2 cells were evaluated.

Epidemiology of tattoo skin disease in bottlenose dolphins Tursiops truncatus from the Sado estuary, Portugal

2003

We report on the epidemiology of tattoo disease in a community of bottlenose dolphins Tursiops truncatus from the Sado estuary, Portugal. The presence of tattoos (T++) and tattoo-like (T+) lesions was examined in 586 photographic records of 35 dolphins taken from 1994 to 1997. Images were rated into 3 categories: good (GI), average (AI) and poor (PI). Dolphins positive for T++ lesions were observed in 19 GI. Dolphins with T+ lesions were seen in 39 GI, 23 AI and 6 PI. For statistical analysis the dolphins were divided into 2 age classes (immature and adult) and the data grouped into 2 periods (1994-1995 and 1996-1997). Minimum prevalence of T++ lesions in 32 dolphins was 21.9% in 1994-1995 …

SHAKESPEARE: VELENO E TRAGEDIA

1999

Veleno: una parola che ricorre con insistenza nelle tragedie di Shakespeare. Quali motivazioni hanno spinto il drammaturgo inglese a inserire in tutte le sue opere almeno una volta il “veleno”? Il saggio indaga le ricorrenze del termine, ma si sofferma anche su un altro aspetto assai rilevante: tutti i personaggi che muoiono per soffocamento sono innocenti, mentre tutti quelli che sono uccisi (o si suicidano) col veleno sono colpevoli. Non può trattarsi di una coincidenza, bensì di una preordinata impostazione dell’impianto drammatico. Il volume così dimostra che in Shakespeare esiste un preciso ordine tripartito che regola le colpe di tutti i personaggi delle tragedie.

Zur Trennung von Unrecht und Schuld im Strafrecht: Sinn und Grenzen in der italienischen Strafrechtswissenschaft

2022

Il lavoro esamina la tenuta della distinzione fra illecito e colpevolezza nel sistema penale italiano, alla luce di un confronto critico con la teoria delle norme che ne viene talvolta indicata come presupposto necessario. Der Beitrag untersucht die Unterscheidung zwischen Unrecht und Schuld im italienischen Strafrechtssystem im Lichte eines kritischen Vergleichs mit der Theorie der Normen, die manchmal als notwendige Voraussetzung dafür angegeben wird.

Life-history trade-offs in a generalist digenean from cetaceans: the role of host specificity and environmental factors

2015

Background Adults and larvae of generalist parasites are exposed to diverse hosts and local environmental conditions throughout their life cycles, thus local adaptation is expected to occur through phenotypic plasticity and/or natural selection. We investigated how the combined effect of cryptic host specificity and local selective pressures could shape reproductive traits of a putative generalist parasite in the oceanic realm. Methods The LSU rDNA, ITS2 and the mt-COI of individuals of the digenean Pholeter gastrophilus (Kossack, 1910) Odhner, 1914 (Heterophyidae Leiper, 1909) from oceanic striped dolphins, Stenella coeruleoalba Meyen, and coastal bottlenose dolphins, Tursiops truncatus Mo…

Bringt die Kombination einer Faszienzügelplastik mit der Kolposuspension nach Burch in der Therapie der weiblichen Stressinkontinenz Vorteile gegenüb…

2003

PURPOSE Despite the development of new surgical techniques, the fascial sling procedure remains an important surgical technique for the treatment of female urinary stress incontinence. An advantage of combining it with an additional Burch colposuspension has been suggested. The objective of our study was to evaluate retrospectively selected patients who had undergone a fascial sling procedure with and without Burch colposuspension. MATERIALS AND METHODS Of a total of 390 females who underwent an incontinence operation at our department between 1990 and 1999, 56 patients had had a fascial sling plasty. A total of 50 patients (89 %) were followed for a median of 59.5 months. The median age wa…

Modelli duecenteschi nell’immaginario narrativo di Paolo Volponi

2008

Il saggio analizza le riprese e gli echi della letteratura duecentesca presenti in Memoriale e nelle altre opere di Paolo Volponi.