Search results for "ONCE"
showing 10 items of 4997 documents
Changes in isokinetic torque and muscular activity of elbow flexors muscles with age
2001
This study examined the influence of aging on torque-angular velocity relationships for elbow flexion and the corresponding muscular activity levels in order to target the mechanisms involved in the eccentric muscle action in older adults. Maximal constant angular torque (CAT) at 90 degrees was measured at different angular velocities for concentric (CON; 60, 120, 180, 240 degrees s(-1)), isometric (ISO) and eccentric (ECC; -60, -120 degrees s(-1)) elbow flexor muscle actions in older (OG; 6 females and 4 males, 64-82 years) and young adult subjects (YG; 6 females, 6 males, 19-24 years) on an isokinetic dynamometer. Myoelectrical activity was quantified on biceps and triceps muscles, using …
Life satisfaction, anxiety, depression and resilience across the life span of men
2009
To determine (a) the relationship between life satisfaction, anxiety, depression and ageing in the male community and (b) to identify the impact of vulnerability factors, personal and social resources on life satisfaction and distress.A stratified random sample of the German male population (N = 2144) was investigated by standardized questionnaires of life satisfaction (FLZ(M)), depression, anxiety (PHQ), resilience (RS-11) and self-esteem (RSS).No age-related change was found regarding overall life satisfaction. Satisfaction with health decreased in midlife (51-60 years), while the importance of health increased. Importance of and satisfaction with partnership and sexuality were only reduc…
An experimental model for the exposure of human ciliated cells to sulfur dioxide at different concentrations
1994
Mucociliary transport is an important nonimmunological defense mechanism of the respiratory tract. The aim of this study was to investigate the effect of sulfur dioxide (SO2) at different concentrations on ciliary beat frequency (CBF). Ciliated cells were obtained from 12 volunteers by nose brush. CBF was quantified using video-interference microscopy. The cells were placed on a polycarbonate membrane in contact with the surface of a reservoir filled with RPMI 1640 (bicarbonate buffered) or Ringer's (electrolyte) solution, allowing the cells to be supplied by capillarity. In an exposure chamber the cells were exposed for 30 min to SO2 2.5-12.5 ppm at 37 degrees C and 100% air humidity. SO2 …
Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis
2021
Background: Knowledge regarding the impact of body composition measures on pharmacokinetics of antipsychotics is limited. Aims: Our aim was to investigate the impact of body weight and body mass index on clozapine pharmacokinetics using a therapeutic drug monitoring database. Methods: A large therapeutic drug monitoring dataset of clozapine plasma concentrations considering three patient subgroups was analysed: a control group (CLZ0, 20–30 kg/m2, n=266), a group with high body mass index (CLZhigh, body mass index ⩾30 kg/m2, n=162) and with low body mass index values (CLZlow, body mass index <20 kg/m2, n=27). Comparisons of plasma and dose-adjusted plasma concentrations (C/D) of clozapine…
Marine sponge collagen: isolation, characterization and effects on the skin parameters surface-pH, moisture and sebum
2002
A previously described isolation procedure for collagen of the marine sponge Chondrosia reniformis Nardo was modified for scaling-up reasons yielding 30% of collagen (freeze-dried collagen in relation to freeze-dried sponge). Light microscope observations showed fibrous structures. Transmission electron microscopy studies proved the collagenous nature of this material: high magnifications showed the typical periodic banding-pattern of collagen fibres. However, the results of the amino acid analysis differed from most publications, presumably due to impurities that still were present. In agreement with earlier studies, sponge collagen was insoluble in dilute acid mediums and all solvents inv…
Automatic numerical-spatial association in synaesthesia: An fMRI investigation
2016
A horizontal mental number line (MNL) is used to describe how quantities are represented across space. In humans, the neural correlates associated with such a representation are found in different areas of the posterior parietal cortex, especially, the intraparietal sulcus (IPS). In a phenomenon known as number-space synaesthesia, individuals visualise numbers in specific spatial locations. The experience of a MNL for number-space synaesthetes is explicit, idiosyncratic, and highly stable over time. It remains an open question whether the mechanisms underlying numerical-spatial association are shared by synaesthetes and nonsynaesthetes. We address the neural correlates of number-space assoc…
Is that me in the mirror? Depersonalisation modulates tactile mirroring mechanisms
2016
Our sense of self is thought to develop through sensory-motor contingencies provided, not only by observing one's own body, but also by mirroring interactions with others. This suggests that there is a strong link between mirroring mechanisms and the bodily self. The present study tested whether this link is expressed at early, implicit stages of the mirroring process or at later, more cognitive stages. We also provide, to the best of our knowledge, the first demonstration of how inter-individual differences in our sense of bodily self may affect mirroring mechanisms. We used somatosensory event-related potentials (SEPs) to investigate the temporal dynamics of mirroring highly self-related …
Animacy matters: ERP evidence for the multi-dimensionality of topic-worthiness in Chinese
2013
Abstract An event-related potential (ERP) study was conducted to investigate how animacy interacts with givenness during topic processing. Both animacy and givenness have been considered as within-discourse factors that contribute to an element׳s potential to form an optimal topic (i.e., topic-worthiness). ERPs were recorded while participants read question–answer pairs, of which the target sentence induced either a continuation or an alternation of a previously introduced topic (i.e., given vs. new). Depending on the context, a potential topic further differed in its animacy from the preceding one (i.e., animate vs. inanimate). The data revealed a robust givenness effect with an N400 reduc…
Trait self-esteem and claimed self-handicapping motives in sports situations
2012
International audience; We examined the relationship between physical self-esteem and claimed self-handicapping among athletes by taking motives into consideration. In Study 1, 99 athletes were asked to report their tendency to engage in claimed self-handicapping for self-protective and self-enhancement motives (trait measures). Low self-esteem athletes reported a higher tendency to engage in claimed self-handicapping for these two motives compared with high self-esteem athletes. Neither low nor high self-esteem athletes reported a preference for one motive over the other. In Study 2, 107 athletes participated in a test that was ostensibly designed to assess high physical abilities - and th…
Determinants of leisure-time physical activity and future intention to practice in Spanish college students
2009
Few studies analyze determinants and patterns of physical activity among college students, so it has not been possible to carry out effective interventions to promote this practice. The aim of this study was to analyze the associations between some personal, social, and environmental determinants, practice of physical activity and future intention to practice in a sample of 639 university students (321 men and 318 women), mean age 21.43 years (+/- 2.78). Physical fitness self-perception, physical activity history, and coach's support to practice physical activity have a direct effect on the practice of physical activity and an indirect effect on future intention to practice, both in men and…