Search results for "ONCE"
showing 10 items of 4997 documents
A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.
2011
International audience; Buchnera aphidicola is an obligate symbiotic bacterium that sustains the physiology of aphids by complementing their exclusive phloem sap diet. In this study, we reappraised the transport function of different Buchnera strains, from the aphids Acyrthosiphon pisum, Schizaphis graminum, Baizongia pistaciae and Cinara cedri, using the re-annotation of their transmembrane proteins coupled with an exploration of their metabolic networks. Although metabolic analyses revealed high interdependencies between the host and the bacteria, we demonstrate here that transport in Buchnera is assured by low transporter diversity, when compared to free-living bacteria, being mostly bas…
L'écriture des documents numériques : Approche ergonomique
2007
Cet ouvrage traite de la conception de documents numériques utilisés en contexte professionnel et étudie en particulier les deux thèmes suivants : le découpage de l'information pour la mise en écran, les organisateurs de structure, de navigation et de mise en relief de l'information. L'influence sur la lecture des dispositifs de mise en forme matérielle et des organisateurs de structure et de navigation est souvent méconnue. Aussi les méthodes destinées à tester le rôle des dispositifs de mise en forme revêtent-elles une importance capitale et sont présentées à la fin de cet ouvrage. Les spécificités des supports (document papier et document numérique) sont également abordées en termes de c…
Design and implementation of the AMIGA embedded system for data acquisition
2021
The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and admin-istrative staff in Malargtie. We are very grateful to the following agencies and organizations for financial support: Comision Nacional de Energla Atomica, Agencia Nacional de Promocion Cientffica y Tec-nologica (ANPCyT) , Consejo Nacional de Investigaciones Cientfficas y Tecnicas (CONICET) , Gobierno de la Provincia de Mendoza, Municipalidad de Malargtie, NDM Holdings and Valle Las Leilas, in gratitude for their continuing cooperation over land access, Argentina; the Australian Research Council; Conselho…
Interaction of allopurinol with phenprocoumon in man.
1977
Conditions in two patients on long-term phenprocoumon (Marcumar®) treatment are reported who had signs of phenprocoumon overdosage when given simultaneously allopurinol. The determination of phenprocoumon plasma concentrations in one patient showed that phenprocoumon accumulates for several weeks during treatment with allopurinol. Signs of phenprocoumon overdosage thus can appear long time after starting allopurinol treatment.
Adsorption of methotrexate and calcium leucovorin onto cholestyramine in vitro.
2003
Abstract Methotrexate (MTX), an antimetabolite of folic acid, is a drug widely used in the treatment of different types of cancer. When high doses are administered, it is necessary to interrupt its action by administering calcium leucovorin (CaL). The main pathway of MTX and CaL elimination in humans occurs through the kidney, but about 10% is excreted in the faeces via the bile. Drugs, foods and sorbents in intestinal lumen modify MTX and CaL reabsorption. Individual and simultaneous studies on the adsorption of MTX and CaL from aqueous phosphate buffer by cholestyramine were carried out in order to calculate the adsorption process of MTX and CaL to cholestyramine, and to characterize the …
Geometric Morphometric Studies in the Human Spine
2019
This chapter overviews the theoretical basics of geometric morphometrics (GM) and reviews its potential for the study of hominin vertebrae and vertebral columns. We show that challenges are related to seriality and the metameric nature of the spine. Measuring a series of vertebrae is a time-consuming process because the necessary sample sizes need to be multiplied by the number of vertebrae composing the spine or its anatomical parts. This is particularly true when measuring 3D semilandmarks of curves and surfaces in virtual anthropology. The lack of independence among vertebral series of a skeleton and the complex conceptual relation between the shape of vertebrae (parts) and the effect of…
Residual Stress Effects on Fatigue Crack Growth in Ti-6Al-4V Friction Stir Welds
2008
Recent studies have illustrated a predominant role of the residual stress on the fatigue crack growth in friction stir welded joints. In this study, the role of the residual stress on the propagation of fatigue cracks orthogonal to the weld direction in a friction stir welded Ti-6Al-4V joint was investigated. A numerical prediction of the fatigue crack growth rate in the presence of the residual stresses was carried out using AFGROW software; reasonable correspondence between the predictions and the experimental results were observed when the effects of residual stress were included in the simulation.
Numerical experimental analysis of hybrid double lap aluminum-CFRP joints
2015
Abstract Due to their reliability and ease of assembly, both the adhesively bonded and the mechanical joints are commonly used in different fields of modern industrial design and manufacturing, to joint composite materials or composites with metals. As it is well known, adhesively bonded joints are characterized by high stiffness and good fatigue life, although delamination phenomena localized near the free edges may limit their use, especially for applications where corrosive environments and/or moisture can lead to premature failure of the bonding. In these cases, a possible alternative is given by the well-known mechanical joints. On the contrary, these last joints (bolted, riveted) requ…
Musical Self-Concept - Presentation of a Multi-Dimensional Model and Its Empirical Analyses
2009
Research on the specific domain of musical self-concept was so far exclusively concerned with musically active subjects (such as performers, music teachers, students, or singing children). In contrast, the starting base of the presented research is that music is a distinct aspect in everyone’s life and personality and that therefore musical self-concept is general and includes a number of domain besides achievement. The presented multi-dimensional model includes (i) non-academic and (ii) dimensions of musical ability. The first section entails representations with regards to “who I am” in music, such as emotional, social, physical, cognitive and spiritual notions, while section two addresse…
Verification and Validation of the Musical Self-Concept Inquiry (MUSCI) to Measure ’Musical Self-Concept’ of German Students at Secondary Education S…
2016
Musical development can be very differently during adolescence and the mechanisms and reasons, which lead to these differences, are often objects of music educational research. To measure the aspects of musical development of German students, the psychometric construct ‘musical self-concept’ can be used. So the first aim of this study was to verify the factor structure of the initial MUSCI-questionnaire to measure ‘musical self-concept’ of German students. The second aim was to re-specify the underlying factor model as well as to validate the renewed sub-facets of the questionnaire with musicspecific background variables (e. g. interest in ‘music’) as well as the construct ‘musical sophisti…