Search results for "ONTOX"

showing 2 items of 2 documents

Safer chemicals using less animals: kick-off of the European ONTOX project

2021

The 3Rs concept, calling for replacement, reduction and refinement of animal experimentation, is receiving increasing attention around the world, and has found its way to legislation, in particular in the European Union. This is aligned by continuing high-level efforts of the European Commission to support development and implementation of 3Rs methods. In this respect, the European project called "ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment" was recently initiated with the goal to provide a functional and sustainable solution for advancing human risk assessment of chemicals without the use of animal…

Artificial intelligenceComputer science010501 environmental sciencesOntology (information science)In Vitro TechniquesAnimal Testing AlternativesToxicology01 natural sciencesRisk Assessment3Rs03 medical and health sciencesIn vitroSAFERAdverse Outcome PathwayToxicity TestsEuropean projectmedia_common.cataloged_instanceAnimalsHumansComputer SimulationEuropean UnionAnimal testingEuropean union0105 earth and related environmental sciencesExposure assessmentmedia_common0303 health sciencesOntologyIn silico030311 toxicology3. Good healthVariety (cybernetics)Gene OntologyRisk analysis (engineering)Systemic toxicityONTOXRisk assessment
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Electrochemical production and use of chlorinated oxidants for the treatment of wastewater contaminated by organic pollutants and disinfection

2021

Abstract In the last years, an increasing attention has been devoted to the use of electrogenerated chlorinated oxidants for the treatment of wastewater polluted by recalcitrant organics and/or for the disinfection of water contaminated by pathogen microorganisms. In this review, more recent and relevant findings were presented and critically discussed. The main advantages and disadvantages of this technique were commented, including the potential formation of toxic chlorinated organic specie and of chlorate and perchlorate or the difficult selection of proper operative parameters, as well as the key points that should be addressed to enhance the use on an applicative scale.

Pollutant02 engineering and technologyContaminationSettore ING-IND/27 - Chimica Industriale E Tecnologica010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesElectrochlorinationActive chlorine speciesWastewater treatmentDisinfectionToxic chlorinated compounds0104 chemical sciencesAnalytical ChemistryWastewaterEnvironmental chemistryElectrochemistryEnvironmental science0210 nano-technology
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