Search results for "ORAC"
showing 10 items of 1142 documents
Gaining or losing PhDs: What are the effects on firms' linkages with universities?
2023
PhD graduates can help companies transfer knowledge from universities to firms. Scholars have analysed the determinants of PhD recruitment by firms and its effects on their innovation activities. However, little is known about what happens when a firm loses employees with PhDs. The aim of this paper is to compare the effects on the relationships of firms with universities when these firms lose PhDs versus when they hire PhDs to work in R&D. These effects may be symmetrical or non-symmetrical depending on the abilities of firms to retain the connections and knowledge acquired by hiring PhDs. We consider four types of relationships: collaboration with universities, universities as a source of…
Determination of essential biomarkers in lung cancer: a real-world data study in Spain with demographic, clinical, epidemiological and pathological c…
2022
Abstract Background The survival of patients with lung cancer has substantially increased in the last decade by about 15%. This increase is, basically, due to targeted therapies available for advanced stages and the emergence of immunotherapy itself. This work aims to study the situation of biomarker testing in Spain. Patients and methods The Thoracic Tumours Registry (TTR) is an observational, prospective, registry-based study that included patients diagnosed with lung cancer and other thoracic tumours, from September 2016 to 2020. This TTR study was sponsored by the Spanish Lung Cancer Group (GECP) Foundation, an independent, scientific, multidisciplinary oncology society that coordinates…
Wider implications of video-assisted thoracic surgery versus open approach for lung metastasectomy
2015
ABSTRACT Lung metastasectomy is considered a safe and potentially curative procedure despite there is not a strong evidence that metastasectomy prolongs long-term survival in patients with lung metastases. Moreover, the debate is open regarding the best approach for lung metastasectomy, video-assisted thoracic surgery versus open approach. A systematic review of literature to clarify what is the best approach to prolong survival in patients with lung metastases was performed. Our study confirms that overall survival is equivalent for video-assisted thoracic surgery and thoracotomy, therefore the ‘gold standard’ surgical treatment for lung metastases remains a point of debate. The choice o…
SMOS REFLEX 2003: L-band emissivity characterization of vineyards
2005
The goal of the Soil Moisture and Ocean Salinity mission over land is to infer surface soil moisture from multiangular L-band radiometric measurements. As the canopy affects the microwave emission of land, it is necessary to characterize different vegetation layers. This paper presents the Reference Pixel L-Band Experiment (REFLEX), carried out in June-July 2003 at the Vale/spl grave/ncia Anchor Station, Spain, to study the effects of grapevines on the soil emission and on the soil moisture retrieval. A wide range of soil moisture (SM), from saturated to completely dry soil, was measured with the Universitat Polite/spl grave/cnica de Catalunya's L-band Automatic Radiometer (LAURA). Concurre…
Systematische Analyse der Geometrie eines definierten Kontrastmittelbolus - Implikationen für die kontrastmittelverstärkte 3D-MR-Angiographie thoraka…
2005
Purpose: Little is known about the dispersion of a defined contrast bolus during its passage through the heart and pulmonary vasculature. The purpose of this study was to analyze factors influencing a defined contrast bolus for ce-MRA of thoracic vessels. Materials and Methods: For analysis of bolus geometry, an ECG-gated saturation-recovery Turbo-Flash sequence with a TI of 20 msec was used. It was acquired axially at the level of the pulmonary trunc, so that with one data acquisition a curve analysis was possible in the ascending and descending aorta, and in the pulmonary trunc. Twenty-nine patients received 3 ml of Gd-DTPA diluted with saline to a total of 20 ml. Contrast injection was d…
CARDIOPROTEZIONE ED ANESTESIA EPIDURA- LE TORACICA: UN CASO DI ISCHEMIA MIOCAR- DICA POSTOPERATORIA
2013
Obiettivo. Analisi dell’effetto cardioprotettivo perioperatorio dell’anestesia peridurale toracica (TEA) in un paziente car- diopatico sottoposto a chirurgia non cardiaca. Materiali e metodi. Paziente di 59 anni affetto da patologia neoplastica, BPCO severa, insufficienza renale cronica e car- diopatia ipertensiva (ASA IV), viene sottoposto ad intervento chirurgico di cistectomia radicale e resezione duodeno-digiu- nale. In fase preoperatoria si posiziona un catetere epidurale (T10) e si somministra un bolo di Levobupivacaina (75 mg) e Fentanest (0,05 mg). Si procede a monitoraggio intraoperato- rio con CardioQ che evidenzia uno stato ipotensivo iniziale con bassa portata e basse resistenze…
Left atrial strain and left atrial stiffness for early detection of cardiotoxicity in cancer patients
2021
Abstract Background Anti-cancer drugs can cause cardiovascular complications. Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) are usually used to identify clinical and subclinical cardiotoxicity. Purpose The aim of our study was to assess the addictional role of left atrial reservoir strain (LAS-S) and left atrial stiffness (LASI – the ratio of E/e' to LAS-S) in identifying patients at higher risk of cardiotoxicity. Methods 102 breast cancer patients (median age 53±9.5 years), without cardiovascular diseases, were enrolled before starting chemotherapy. Electrocardiogram and transthoracic echocardiogram (conventional measurements based on EACVI recommendations;…
Oratio Ioannis Baptistae Adrianii Habita Florentiae in sacris funebribus Caroli V Caesaris Augusti.
1562
Sign.: A8 Port. arquitectònica amb grav. xil.
Preclinical atherosclerosis and metabolic syndrome increase cardio- and cerebrovascular events rate: a 20-year follow up
2013
BACKGROUND: Intima-media thickness (IMT) is a validated marker of preclinical atherosclerosis and a predictor of cardiovascular events. PATIENTS: We studied a population of 529 asymptomatic patients (age 62 ± 12.8 years), divided into two groups of subjects with and without Metabolic Syndrome (MetS). METHODS: All patients, at baseline, have had a carotid ultrasound evaluation and classified in two subgroups: the first one without atherosclerotic lesions and the second one with preclinical atherosclerosis (increased IMT or asymptomatic carotid plaque). Cardiovascular endpoints were investigated in a 20-years follow-up. RESULTS: There were 242 cardiovascular events: 144 among patients with Me…
Non-coronary atherosclerosis
2014
International audience; During the last decades, the clinical and research interest in atherosclerosis has been mostly focused on coronary arteries. After the publications of the European Society Guidelines and AHA/ACC Guidelines on Peripheral artery diseases, and of the Registry REduction in Atherothrombosis for Continued Health Registry, there has been an increased interest in atherosclerosis of the lower extremity arteries and its presence in multifocal disease. However, awareness in the general population and the medical community of non-coronary artery diseases, and of its major prognostic implications remain relatively low. The aim of this general review stemming out of an ESC Working…