Search results for "ORAC"
showing 10 items of 1142 documents
El uso de la narrativa transmedia en la enseñanza de geografía
2016
Este trabajo tuvo como objetivo principal construir una reflexión y análisis sobre el uso de tecnologías de la información y la comunicación en la enseñanza de geografía utilizando la narrativa transmedia y tomando como caso de estudio el “Proyecto transmedia tráfico carioca”, desarrollado en el Colegio Pedro II campus Realengo II desde 2012. Sin embargo, para construir esta investigación, fue necesaria una profundización en diversos aspectos relacionados con la enseñanza de geografía. ElProyecto transmedia Trafico carioca comenzó a desarrollarse en el año 2012 a partir de las lecturas y discusiones en mi doctorado en la Universidad del Estado de Rio de Janeiro. La elección del tema relacio…
MetAphAs Test. Metalanguage in Aphasia Assessment.
2018
Test MetAphAs: La evaluación del metalenguaje en la afasia (Rosell-Clari & Hernández-Sacristán, 2018) es una versión adaptada y abreviada de Rosell Clari & Hernández Sacristán, 2014). Esta prueba fue desarrollada inicialmente para evaluar las habilidades metalingüísticas naturales en personas con afasia (Hernández-Sacristán, Rosell-Clari, Serra-Alegre y Quiles-Climent, 2012). Las habilidades metalingüísticas naturales se refieren al uso del lenguaje que revela reflexividad (Hockett, 1960); es decir, la distancia perceptiva del hablante con respecto a su propio comportamiento verbal (Werner & Kaplan, 1978). Esta autoconciencia del lenguaje nos permite monitorear nuestros propios comportamien…
Nipple-sparing mastectomy and breast reconstruction with a deep inferior epigastric perforator flap using thoracodorsal recipient vessels and a low l…
2018
Background Nipple-sparing mastectomy poses challenges in providing esthetically-pleasing immediate autologous breast reconstruction. This study was to investigate the outcomes of nipple-sparing mastectomy with breast reconstruction using free abdominal flaps between two different recipient sites. Methods Between 2010 and 2016, 79 patients who underwent nipple-sparing mastectomy with autologous breast reconstruction using thoracodorsal (TD) vessels in 30 cases or internal mammary (IM) vessels in 49 cases were investigated. Demographics, intraoperative findings, complications, and quality of life using Breast-Q questionnaire were compared between two groups. Results All flap survived. There w…
Phosphorylation and activation of endothelial nitric oxide synthase by red fruit (Pandanus conoideus Lam) oil and its fractions
2020
Abstract: Ethnopharmacological relevance Red fruit (Pandanus conoideus Lam) oil (RFO) is utilized by inhabitants of the Papua Island to treat diseases such as infections, cancer, and cardiovascular disease, but the mechanism of action is unknown. Aim of the study We have recently shown that RFO stimulates nitric oxide (NO) production in endothelial cells. The present study was conducted to investigate the molecular mechanism of endothelial NO synthase (eNOS) activation by RFO. Materials and methods NO production by endothelial cells was determined with electron paramagnetic resonance. The vascular function of isolated mouse aorta was examined using a wire myograph system. Phosphorylation of…
Aging-related endothelial dysfunction in the aorta from female senescence-accelerated mice is associated with decreased nitric oxide synthase express…
2013
The present study investigated the time-course for aging-associated effects on contractile and relaxing vascular responses and nitric oxide (NO) production in the aorta from female senescence-accelerated resistant (SAMR1) and prone (SAMP8) mice. Both SAMR1 and SAMP8 were studied at three different ages: 3 (young), 6 (middle age) and 10 (old) months. Concentration-response curves to phenylephrine (10(-8) to 10(-5) M) or acetylcholine (10(-9) to 10(-5) M) were performed in the aortic rings in the absence or in the presence of NO synthase (NOS) inhibitor L-NAME (10(-4) M). Protein and gene expression for endothelial NOS (eNOS) was determined by immunofluorescence, Western blot and real-time PC…
Correcting for Potential Barriers in Quantum Walk Search
2015
A randomly walking quantum particle searches in Grover's $\Theta(\sqrt{N})$ iterations for a marked vertex on the complete graph of $N$ vertices by repeatedly querying an oracle that flips the amplitude at the marked vertex, scattering by a "coin" flip, and hopping. Physically, however, potential energy barriers can hinder the hop and cause the search to fail, even when the amplitude of not hopping decreases with $N$. We correct for these errors by interpreting the quantum walk search as an amplitude amplification algorithm and modifying the phases applied by the coin flip and oracle such that the amplification recovers the $\Theta(\sqrt{N})$ runtime.
Biosorption of green and black tea polyphenols into Saccharomyces cerevisiae improves their bioaccessibility
2015
Infusions of green tea (GT) and black tea (BT) and the use of Saccharomyces cerevisiae as a natural matrix were employed to check the impact of biosorption on the possible fate of tea polyphenols in the gastrointestinal tract in terms of bioaccessibility and total antioxidant capacity (TEAC and ORAC assays). The maximum biosorption yields obtained were 47.61 ± 11.57 and 99.68 ± 5.25 mg/g from GT and BT infusions, respectively. A significant increase (p < 0.05) in the recovery of phenolic compounds was shown after in vitro digestion. The bioaccessible fractions generally exhibited higher antioxidant capacities in both tea infusions and suspensions of S. cerevisiae versus non-digested samples…
Characterization of softwood and hardwood lignoboost kraft lignins with emphasis on their antioxidant activity
2014
Fractionation of softwood and hardwood LignoBoost kraft lignins, using sequential extraction with organic solvents of increasing hydrogen-bonding ability (dichloromethane, n-propanol, and methanol), was carried out. Using SEC, analytical pyrolysis, FTIR and UV/VIS spectroscopy, and chemical analytical methods, four fractions were obtained and characterized in terms of their yield, composition, functionality, lignin structural features, and antioxidant properties. In tests with free radicals (ABTS●+, DPPH●, O2●-) and the ORAC (oxygen radical absorbance capacity) assay, the high radical scavenging capacity of the lignin’s soluble fractions was demonstrated. The antioxidant activity of the fra…
Prediction of mass fluxes in the pervaporation process of the ethanol dehydration, based on the free volume theory
2014
Metodę obliczania współczynników dyfuzji Maxwella-Stefana opartą na współczynnikach dyfuzji własnej przewidywanych wg zależności wynikających z teorii wolnych objętości, zastosowano do obliczania strumieni masy w procesie perwaporacyjnego odwadniania etanolu na membranie z alkoholu poliwinylowego PVA. Parametry metody wolnych objętości dla badanego układu wyznaczono oraz obliczono stężenia równowagowe w PVA stosując zmodyfikowaną metodę UNIFAC-FV a następnie obliczono udziały masowe w permeacie oraz współczynniki wzbogacenia. Obliczenia przeprowadzono dla danych eksperymentalnych opublikowanych w pracy [3]. Wyniki obliczeń porównano z wynikami uzyskanymi na instalacji doświadczalnej.
Isolated Lung Perfusion as an Adjuvant Treatment of Colorectal Cancer Lung Metastases: A Preclinical Study in a Pig Model
2012
BackgroundThe lung is a frequent site of colorectal cancer (CRC) metastases. After surgical resection, lung metastases recurrences have been related to the presence of micrometastases, potentially accessible to a high dose chemotherapy administered via adjuvant isolated lung perfusion (ILP). We sought to determine in vitro the most efficient drug when administered to CRC cell lines during a short exposure and in vivo its immediate and delayed tolerance when administered via ILP.MethodsFirst, efficacy of various cytotoxic molecules against a panel of human CRC cell lines was tested in vitro using cytotoxic assay after a 30-minute exposure. Then, early (operative) and delayed (1 month) tolera…