Search results for "ORAL MUCOSA"
showing 10 items of 184 documents
The basis, technique and indication for cryosurgery in tumours of the oral cavity and face
1975
The fundamentals of clinical application of crysurgery with very deep freezing of tissues is based on the necrotising effect of extreme cooling. The freezing of extracellular and intracellular free fluid leads to irreversible cell damage, because of a shift of electrolyte concentration to toxic values, and a direct lesion of internal cellular structures. The lesion due to cold occurs as a clear demarcation from the healthy surrounding, almost completely painlessness, and rapid healing without complication. For clinical application in the head and neck, there are cooling instruments fitted with specially shaped, exchangeable probe heads. Convincing results were achieved in the cryosurgical t…
Oral mucosa of coeliac disease patients produces antiendomysial and antitransglutaminase antibodies: the diagnostic usefulness of an in vitro culture…
2007
Summary Background Antiendomysial (EmA) and antitransglutaminase (anti-tTG) antibodies are the most specific indirect marker of coeliac disease (CD). It is not known whether the oral mucosa of patients with CD is able to produce these antibodies or not. Aims To evaluate the ability of the oral mucosa of patients with CD to produce antibodies in an in vitro culture system. Patients and methods Twenty-eight patients with new diagnosis of CD (15 adults and 13 children) and 14 adult subjects with other diseases (controls) were studied. All underwent oral mucosa biopsy and subsequent EmA and anti-tTG assays on the mucosa culture medium. Results Sensitivity and specificity of EmA and anti-tTG…
Oral mucosal lesions and their association with tobacco use and qat chewing among Yemeni dental patients.
2014
Objectives: This study aimed to assess the prevalence of oral mucosal lesions (OMLs) in patients attending outpa - tient dental clinics in Sana`a university, Yemen, and to evaluate the association of such lesions with age, gender, and oral habits. Materials and Methods: This cross-sectional study included 409 subjects (272 males, 137 females, age: 15-86 years). Detailed clinical examination was performed in accordance with international criteria. Patient history in - cluded age, gender, education, denture wearing and risk habits (tobacco use and qat chewing). Data were analyzed using SPSS 19.00. Results: The prevalence of OMLs was 58.4% with a significant difference between men (63.6%) and …
Quantification of colloid bodies in Oral Lichen Planus and Oral Lichenoid Reaction - A Histochemical Study
2011
Aim: Oral lichen planus and oral lichenoid reaction are familiar keratotic lesions found on the oral mucosa. Colloid bodies can be microscopically appreciated in both these lesions. The aim of this study was to identify as well as examine the frequency of colloid bodies in oral lichen planus and oral lichenoid reaction by histochemical means. Method: The material for the study included 12 formalin-fixed paraffin-embedded tissue blocks (7 oral lichen planus and 5 oral lichenoid reaction), retrieved from the Department of Oral Pathology and Microbiology, MCODS, Manipal. Sections stained with hematoxylin-eosin (H&E) and periodic acid-Schiff (PAS) with diastase to identify, locate and examine t…
US7 Oral mucosal ulcerations
2006
Oral mucosal ulcer represents a localized loss of the lining epithelium and sometimes also of the subjacent connective tissue. It could be persistent or recurrent and also single or multiple. As regards those persistent a large variety of etiologic factors have been suggested: this kind of ulcers could be a sign of a localised direct reaction to any physical/chemical injury or due to a drug-related reaction (e.g. by chemotherapy). Mucosal ulceration could also occur in a multiplicity of diseases such as neoplasia, infection, immune-mediated disease or as sign of systemic diseases (e.g. of blood, skin or gastrointestinal tract). A correct diagnosis needs to collect as carefully as possible s…
Oral manifestations of eating disorders: a critical review.
2008
Background: Eating disorders (ED) are a group of psychopathological disorders affecting patient relationship with food and her/his own body, which manifests through distorted or chaotic eating behavior; they include anorexia nervosa, bulimia nervosa and ED not otherwise specified and may be burdened with life-threatening complications. As oral manifestations of ED can occur in many phases of disease progression, they play a significant role in assessment, characterization and prognosis of ED. Methods: Mucosal, dental, and salivary abnormalities associated with ED have been reviewed. Relations between oral menifestations and pathogenesis, management and prognosis of ED have been critically…
Oral lichen planus: A look from diagnosis to treatment.
2013
Abstract: Oral lichen planus (OLP) is a chronic mucocutaneous disease of unknown etiology. Its pathogenesis is multifactorial and it may affect the oral mucosa, skin and other mucous membranes. Diagnosis is based on clinic and histopathology; direct immunofluorescence techniques can also be of use. It affects about one to two percent of the population, mainly women between the fifth and sixth decades of life. In the mouth, the most affected area is the buccal mucosa, followed by the gums, tongue and/or palate. Its three most representative clinical forms are reticular, erythematous and erosive; evolution depends on the type it is. Lesion treatment is determined by the clinical form and, si…
Prevalence of oral mucosal lesions in a brazilian military police population.
2014
Background Data obtained from oral health surveys are very important for identifying disease-susceptible groups and for developing dental care and prevention programs. So, the purpose of the current article was to investigate the prevalence of oral mucosa lesions (OMLs) in a population of Brazilian police. Material and Methods Interviews and oral cavity examinations were performed on a sample of 395 police officers who were randomly selected by the calibrated researcher. The number of individuals was obtained by a sample calculation using the finite population correction. The diagnostic criteria were based on the WHO (1997) criteria and adapted to Brazilian surveys. Results In total, 8.61% …
Oral potentially malignant disorders: is malignant transformation predictable and preventable?
2014
Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence is approximately 1% while the annual malignant transformation ranges from 2% to 3%. At present, there are no reliable clinicopathological or molecular predicting factors of malignant transformation that can be used in an individual patient and such event can not truly be prevented. Furthermore, follow-up programs are of questionable value in this respect. Cessation of smoking habits may result in regression or even disappearance of the leukoplakia and will diminish the risk of cancer development either at the site of the leukoplakia or elsewhere in the mouth or the upper aerodigestive tract. The…
The production of the oral mucosa of antiendomysial and anti-tissue-transglutaminase antibodies in patients with celiac disease: a review.
2010
Celiac disease (CD) is a lifelong, T cell—mediated enteropathy, triggered by the ingestion of gluten and related prolamins in genetically susceptible subjects, resulting in minor intestinal mucosal injury, including villous atrophy with crypt hyperplasia and intraepithelial lymphocytosis, and subsequent nutrient malabsorption. Although serological tests for antiendomysial (EMA) and anti—tissue transglutaminase (anti-tTG) autoantibodies are used to screen and follow up on patients with CD, diagnostic confirmation is still based on the histological examination of the small intestinal mucosa. Although the small intestinal mucosa is the main site of the gut involved in CD, other mucosal surface…