Search results for "ORC"

showing 10 items of 4623 documents

Stationary sets of the mean curvature flow with a forcing term

2020

We consider the flat flow approach for the mean curvature equation with forcing in an Euclidean space $\mathbb R^n$ of dimension at least 2. Our main results states that tangential balls in $\mathbb R^n$ under any flat flow with a bounded forcing term will experience fattening, which generalizes the result by Fusco, Julin and Morini from the planar case to higher dimensions. Then, as in the planar case, we are able to characterize stationary sets in $\mathbb R^n$ for a constant forcing term as finite unions of equisized balls with mutually positive distance.

osittaisdifferentiaaliyhtälötMean curvature flowForcing (recursion theory)Mean curvatureEuclidean spaceApplied Mathematics010102 general mathematicsMathematical analysisstationary setscritical setsvariaatiolaskenta01 natural sciences35J93Term (time)010101 applied mathematicsMathematics - Analysis of PDEsFlow (mathematics)forced mean curvature flowBounded functionFOS: Mathematics0101 mathematicsConstant (mathematics)AnalysisAnalysis of PDEs (math.AP)MathematicsAdvances in Calculus of Variations
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Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma

2018

Hepatocellular carcinoma (HCC) is a highly malignant tumor that responds very poorly to existing therapies, most probably due to its extraordinary inter- and intra-tumor molecular heterogeneity. The modest therapeutic response to molecular targeted agents underlines the need for new therapeutic approaches for HCC. In our study, we took advantage of well-characterized human HCC cell lines, differing in transcriptomic subtypes, DNA mutation and amplification alterations, reflecting the heterogeneity of primary HCCs, to provide a preclinical evaluation of the specific heat shock protein 90 (HSP90) inhibitor AUY922 (luminespib). Indeed, HSP90 is highly expressed in different tumor types, but it…

p53MaleCancer ResearchCellTranscriptome0302 clinical medicineHCCbeta CateninAged 80 and overLuminespibAUY922Liver NeoplasmsHep G2 CellsSorafenibMiddle AgedUp-RegulationGene Expression Regulation Neoplasticmedicine.anatomical_structureOncologyCaspases030220 oncology & carcinogenesisHepatocellular carcinomaFemaleNUPR1medicine.drugAdultSorafenibCarcinoma Hepatocellularβ-CateninMice NudeAntineoplastic AgentsSmall Molecule Libraries03 medical and health sciencesDownregulation and upregulationIn vivoCell Line TumormedicineHSP90AnimalsHumansHSP90 Heat-Shock ProteinsAgedCell growthbusiness.industryMcl-1IsoxazolesResorcinolsHCCSmedicine.diseasedigestive system diseasesMutationCancer researchTranscriptomebusinessInternational Journal of Cancer
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Interactions of membranes with coarse-grain proteins: a comparison

2012

We study the interactions between lipid bilayers and rigid transmembrane proteins by Monte Carlo simulations of generic coarse-grain models. Different popular protein models are considered and compared with each other, and key parameters such as the hydrophobicity and the hydrophobic mismatch are varied systematically. Furthermore, the properties of the membrane are manipulated by applying different tensions. The response of the membrane to the insertion of single proteins is found to be mostly generic and independent of the choice of the protein model. Likewise, the orientational distributions of single proteins depend mainly on the hydrophobic mismatch and the hydrophobicity of the protei…

pacs:87.16.D; 87.15.K; 02.70.Uu; 87.14CcPhysicsNucleationGeneral Physics and AstronomyInterbilayer forces in membrane fusion530Transmembrane proteinHydrophobic mismatchMembraneLattice proteinBiophysicsddc:530Lipid bilayerHydrophobicity scalesNew Journal of Physics
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Om dere vil høre hvordan jeg har det? : en litteraturstudie som omhandler barns opplevelse av alvorlige foreldrekonflikter og hva som kan bidra til å…

2016

Masteroppgave psykisk helsearbeid ME504 - Universitetet i Agder 2016 The purpose of this thesis is to convey knowledge about how children experience serious parental conflicts and how to decrease the negative impact these conflicts has on the children involved. A literature review has been chosen as the scientific method while working with this study. A comprehensive search in different scientific databases has been performed, in a process in which English words have been used. This study is an integrative review where a combination of different approaches allow me to summarize empirical and theoretical literature into comprehensive knowledge about a phenomenon. The theoretical perspectives…

parental conflictME504VDP::Medisinske Fag: 700::Helsefag: 800skilsmisseattachment behaviorVDP::Samfunnsvitenskap: 200::Psykologi: 260family therapydivorceparent-child relationschildrens experiences
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Relational Dialectics in Intercultural Couples' Relationships

2011

parisuhdeintercultural dialecticsintercultural couplesrelational dialecticskulttuurienvälinen viestintäkonfliktitneuvottelutrelationaalinen dialektiikkaintercultural relationshipsepävarmuusristiriidatkulttuurienvälinen tutkimusintercultural relational forcesmonikulttuurinen avioliittokulttuurierotexternal dialecticsparisuhdeviestintäongelmatkulttuuri-identiteettikulttuurienvälisyysvalta
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Party autonomy regarding jurisdiction under the property regimes regulations

2021

The main accomplishment of the Property Regimes Regulations lies in their bringing more coherence into the cross-border family law adjudication. In the field of international jurisdiction, they strive to align the competence in couples? patrimony disputes to that in succession and in separation proceedings, or else to align the competence of the courts to the applicable law. These tendencies are clearly visible in the Regulations? provisions on choice of court agreements. Namely, the Regulations allow for such agreements, but severely limit parties? choice and the possible effects of these clauses. When succession or separation proceedings are pending, it is often only possible to institute…

party autonomy.registered couples? propertyit is often only possible to institute patrimonial disputes at the same court as the said proceedings. When proceedings concerning matrimonial or registered partners? property are initiated without previously pending succession or divorce proceedingshoweveror else to align the competence of the courts to the applicable law. These tendencies are clearly visible in the Regulations? provisions on choice of court agreements. Namelyanalogy with other EU regulations and the CJEU case-law can be of help. The critical eye of the doctrine isrégimen económico-matrimonialRegulation 1104/2016mainly cast on the unpredictable fate of the choice of court agreements under the Regulations. The paper analyses the complex regulation of the choice-ofcourt agreements in the Property Regimes Regulationsautonomía de parte. 274 291draws attention to open questions and provides possible answers. Choice-of-court agreementjurisdictionmatrimonial propertybut severely limit parties? choice and the possible effects of these clauses. When succession or separation proceedings are pendingthey strive to align the competence in couples? patrimony disputes to that in succession and in separation proceedings:CIENCIAS JURÍDICAS [UNESCO]parties can avail themselves of a fairly limited list of options to choose a court from. The Regulations leave several questions regarding choice of court agreements unanswered. Oftenjurisdicciónthe Regulations allow for such agreementsAcuerdo de elección del fororégimen de parejas registradasor else when the necessary consent to the joinder is not given2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113562 Party autonomy regarding jurisdiction under the property regimes regulations Kramberger ?kerlJerca The main accomplishment of the Property Regimes Regulations lies in their bringing more coherence into the cross-border family law adjudication. In the field of international jurisdictionReglamento 1103/2016UNESCO::CIENCIAS JURÍDICASRegulation 1103/2016Reglamento 1104/2016
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El procés de patrimonialització de les festes de la Mare de Déu de la Salut d'Algemesí (1959-2020)

2022

L’objecte d’estudi d’aquesta investigació és el procés de patrimonialització de les festes de la Mare de Déu de la Salut d’Algemesí –en endavant la Festa–. Des de 1880, la Festa s’estructura en una trilogia de seguicis processionals (la Processó de les Promeses, la Processoneta del Matí i la Processó de Volta General), realitzats els dies 7 i 8 de setembre, cada un amb un itinerari diferent i en el qual participen una sèrie de danses (Muixeranga, Nova Muixeranga, Bastonets, Arquets, Carxofa, Pastorets, Llauradores i Tornejants), la música que les acompanya, realitzada en la majoria de les danses amb dolçaina i tabal, i una sèrie d'elements religiosos, el més important la imatge de la Mare d…

patrimoniidentitat col·lectivafesta:ANTROPOLOGÍA [UNESCO]camp de forcespatrimoni immaterialpatrimonialitzaciócomunitatsímbolmuixerangaMare de Déu de la SalutUNESCO::ANTROPOLOGÍAturistització
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An Extremely Rare Case of Disseminated Peritoneal Leiomyomatosis with a Pelvic Leiomyosarcoma and Omental Metastasis after Laparoscopic Morcellation:…

2022

Minimally invasive treatment of uterine fibroids usually requires a power morcellation, which could be associated with several complications. A rare sequela is disseminated peritoneal leiomyomatosis. Indeed, recurrence or metastasis in these cases could be attributed to iatrogenic or under-evaluation of primary tumors, although a subset of cases is a sporadic sample of biological progression. We present an extremely rare case of a patient who underwent laparoscopic morcellation and after 12 years developed a pelvic leiomyosarcoma with two omental metastases, disseminated peritoneal leiomyomatosis with a parasite leiomyoma with bizarre nuclei and a parasite cellular leiomyoma simultaneously.…

pelvic leiomyosarcomaDisseminated peritoneal leiomyomatosidisseminated peritoneal leiomyomatosisClinical BiochemistryPelvic leiomyosarcoma.Omental metastasiomental metastasisLaparoscopic morcellationSettore MED/40 - Ginecologia E Ostetriciadisseminated peritoneal leiomyomatosis; laparoscopic morcellation; omental metastasis; pelvic leiomyosarcoma
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La tributación de la pensión compensatoria como consecuencia de la separación o divorcio en españa

2016

The compensation pension is provided for in the Civil Code for cases of separation or divorce in which there are an economic imbalance between the former spouses. This institution generates tax consequences for the taxpayer who paid compensation as well as for the recipient. This article presents and analyzes the tax regime for ex-spouses derived as a result of the establishment of the compensation pension. La pensión compensatoria está contemplada en el Código Civil para los casos de separación o divorcio en los que se produce un desequilibrio económico en entre los excónyuges. Esta institución genera unas consecuencias fiscales para el obligado tributario que debe abonar la compensación, …

pensión compensatoria:CIENCIAS JURÍDICAS [UNESCO]separationrégimen tributariotax regimeresolución judicialdivorceCiencias jurídicasUNESCO::CIENCIAS JURÍDICAScompensation pensionCiencias jurídicas. Generalidadesseparacióndivorciojudicial decision
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Application of the Chinese Version of the BIS/BAS Scales in Participants With a Substance Use Disorder: An Analysis of Psychometric Properties and Co…

2020

Carver and White developed the Behavioral Inhibition/Behavioral Activation Scales (the BIS/BAS Scales) based on Reinforcement Sensitivity Theory proposed by Gray. Subsequent studies proposed that substance abuse was closely related to Behavioral Inhibition System (BIS) and Behavioral Activation System (BAS). However, researches on the psychometric properties of the BIS/BAS scales in clinical samples are scarce. The present study was conducted to analyze the applicability of the BIS/BAS scales in a sample suffering from a substance use disorder (SUD) and undergoing treatment in compulsory detoxification institutions (n = 1117). Meanwhile, 822 community residents were selected for comparison.…

people with a substance use disorderlcsh:BF1-990educationBehavioral InhibitionimpulsivityReinforcement sensitivity theorypsychometric propertiesImpulsivity050105 experimental psychology03 medical and health sciences0302 clinical medicineCronbach's alphamedicinePsychology0501 psychology and cognitive sciencesBig Five personality traitsGeneral PsychologyOriginal Research05 social sciencesConstruct validityBehavioral activationmedicine.diseaseBehavioral ActivationConfirmatory factor analysisSubstance abuselcsh:Psychologyself-control abilitymedicine.symptomPsychology030217 neurology & neurosurgeryClinical psychologyFrontiers in Psychology
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