Search results for "OSA"

showing 10 items of 9388 documents

Circadian gastric acidity in Helicobacter pylori positive ulcer patients with and without gastric metaplasia in the duodenum.

1996

BACKGROUND: The presence of gastric metaplasia allows helicobacter pylori to colonise the duodenum and this condition is thought to be acquired as a response to acid hypersecretion. This functional disorder, however, is present only in a subgroup of duodenal ulcer patients and, in addition, surface gastric metaplasia has been frequently found in the proximal duodenum of normal subjects and patients with non-ulcer dyspepsia, who cannot be certainly considered as acid hypersecretors. AIMS: To clarify the role of acid in inducing gastric type epithelium in the duodenum. This study aimed at assessing whether the pattern of circadian gastric acidity differs between H pylori positive duodenal ulc…

AdultMalemedicine.medical_specialtyDuodenumSpirillaceaeGastroenterologyEpitheliumHelicobacter InfectionsGastric AcidInternal medicineMetaplasiaBiopsymedicineHumansAntrumMonitoring PhysiologicAnalysis of VarianceMetaplasiabiologymedicine.diagnostic_testHelicobacter pyloribusiness.industrydigestive oral and skin physiologyStomachGastroenterologyHistologyHelicobacter pyloriHydrogen-Ion ConcentrationMiddle Agedbiology.organism_classificationdigestive system diseasesCircadian Rhythmmedicine.anatomical_structureGastric MucosaDuodenal UlcerDuodenumFemaleGastritismedicine.symptombusinessResearch Article
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The Buccal Mucosal Graft For Urethral Reconstruction: A Preliminary Report

1992

Autologous buccal mucosa as a substitute for urethral epithelium was studied in 2 dogs and used in 6 patients with difficult urethral reconstruction problems. The indications for an operation in these patients were failed hypospadias repairs with limited skin in 3, severe structure disease after hypospadias repair in 1, a short urethra in 1 and epispadias in 1. Three urethral fistulas and 1 meatal stenosis occurred in 3 patients. No urethral stricture or diverticulum was noted, and the final outcome was good functionally and cosmetically in all patients. This technique is useful for urethral reconstruction when local skin is not available.

AdultMalemedicine.medical_specialtyEpispadiasAdolescentUrethral strictureUrologyEpispadiasDogsPostoperative ComplicationsUrethramedicineAnimalsHumansChildHypospadiasbusiness.industryMouth MucosaInfantBuccal administrationCheekmedicine.diseaseMeatal stenosisSurgeryPlastic surgerymedicine.anatomical_structureUrethraHypospadiasChild PreschoolSurgical Procedures OperativeTissue TransplantationbusinessJournal of Urology
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Accuracy of staging in early oesophageal cancer using high resolution endoscopy and high resolution endosonography: a comparative, prospective, and b…

2004

The increasing use of endoscopic resection for curative treatment of early oesophageal cancers requires accurate staging before therapy. In a prospective blinded trial, we compared staging of early oesophageal carcinoma using high resolution endoscopy (HR-E) with staging using high resolution endosonography (HR-EUS).A total of 100 patients (89 men, 11 women; mean age 63.9 (10.8) years (range 31-91)) with a suspicion of early oesophageal adenocarcinoma (n = 81) or squamous cell carcinoma (n = 19) were enrolled in the study. After endoscopic staging with high resolution video endoscopy by two experienced endoscopists, HR-EUS was performed by an experienced endosonographer who was blinded to t…

AdultMalemedicine.medical_specialtyEsophageal NeoplasmsHigh resolutionAdenocarcinomaEndosonographySubmucosamedicineCarcinomaHumansSingle-Blind MethodProspective StudiesEsophagusProspective cohort studyAgedNeoplasm StagingAged 80 and overmedicine.diagnostic_testbusiness.industryGastroenterologyReproducibility of ResultsCancerMiddle Agedmedicine.diseasedigestive system diseasesSurgeryEndoscopyOesophagusmedicine.anatomical_structureCarcinoma Squamous CellAdenocarcinomaFemaleEsophagoscopyRadiologybusinessGut
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Baseline characteristics and outcome in Romanian patients with Gaucher disease type 1.

2009

Abstract Background/aim To present clinical and genetic characteristics of all Romanian patients with Gaucher disease type 1, in whom specific diagnosis has been confirmed by enzymatic and molecular methods and to analyze their outcome with and without enzymatic replacement therapy (ERT). Patients, methods There are fifty patients (F/M — 1.63/1) with Gaucher disease type 1. Clinical status, haemoglobin, thrombocytes, hepatic/splenic volume, bone mineral density and severity score were assessed at baseline and every six months thereafter. Thirty-nine patients (78%) received imiglucerase (44.4 ± 13.6 U/kg/2 weeks) for 3.1 +/− 1.4 years. Results Based on general prevalence data, our group repr…

AdultMalemedicine.medical_specialtyEvery Six MonthsBone diseaseImigluceraseAdolescentGenotypeDiseaseGastroenterologyYoung AdultInternal medicineGenotypeInternal MedicinemedicineHumansPlateletAge of OnsetChildAllelesBone mineralGaucher Diseasebusiness.industryRomaniaInfantAnemiaMiddle Agedmedicine.diseasePrognosisThrombocytopeniaSurgeryHexosaminidasesChild PreschoolMutationSplenomegalyGlucosylceramidaseFemalebusinessVisceromegalymedicine.drugEuropean journal of internal medicine
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Effect of manual therapy versus proprioceptive neuromuscular facilitation in dynamic balance, mobility and flexibility in field hockey players. A ran…

2018

To compare the effectiveness of a specific Manual Therapy (MT) protocol applied to field hockey players (FHP), versus a Proprioceptive Neuromuscular Facilitation (PNF) protocol, in the improvement of dynamic balance, active range of movement and lumbar flexibility one-week and four-weeks after the treatment.Randomized controlled trial. Participants were assigned to 2 groups: MT and PNF. 30 min' sessions were performed once a week for three weeks. Three evaluations were performed: basal, one-week and four-weeks post-treatment.University of Valencia (Spain).22 in MT group and 20 in PNF group.Dynamic Balance, measured with Star Excursion Balance Test; Active Range of Motion (ROM), using a manu…

AdultMalemedicine.medical_specialtyFlexibility (anatomy)Field hockeyAdolescentPhysical Therapy Sports Therapy and Rehabilitationlaw.invention03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationRandomized controlled triallawMuscle Stretching ExercisesmedicineHumansOrthopedics and Sports MedicineKneeRange of Motion ArticularDynamic balancePostural Balance030222 orthopedicsHipProprioceptionArthrometry Articularbusiness.industryLumbosacral Region030229 sport sciencesGeneral MedicineProprioceptionMusculoskeletal ManipulationsBiomechanical Phenomenamedicine.anatomical_structureHockeyAthletesAthletic InjuriesFemaleManual therapyAnkleAnklebusinessRange of motionPhysical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
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Capsule Endoscopy versus Push Enteroscopy in Patients with Occult Gastrointestinal Bleeding

2003

Background Wireless capsule endoscopy is a new method enabling non-invasive diagnostic endoscopy of the entire small intestine. In this study we prospectively examined the diagnostic precision of capsule endoscopy compared with push enteroscopy in patients with occult gastrointestinal bleeding. Methods Between July 2001 and October 2002 we examined 48 patients with suspected disorders of the small intestine using capsule endoscopy. 33 patients with obscure bleeding (19 men, 14 women, mean age 58 +/- 23 years) were prospectively examined using capsule endoscopy and push enteroscopy. Results On average, the patients had been suffering from chronic gastrointestinal bleeding for 30 +/- 36 (1-12…

AdultMalemedicine.medical_specialtyGastrointestinal bleedingAdolescentEndoscopeVideo RecordingCapsulesIleumSensitivity and SpecificityGastroenterologylaw.inventionDiagnosis DifferentialCapsule endoscopylawInternal medicineIntestine SmallImage Processing Computer-AssistedmedicineHumansProspective StudiesIntestinal MucosaAngiodysplasiaAgedAged 80 and overmedicine.diagnostic_testbusiness.industryGastroenterologyCapsuleEquipment DesignMiddle Agedmedicine.diseaseDiverticulosisSurgeryEndoscopyEndoscopes GastrointestinalIntestinal Diseasesmedicine.anatomical_structureChronic DiseaseFemaleGastrointestinal HemorrhagebusinessZeitschrift für Gastroenterologie
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Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis

2006

Objectives: Three recent studies revealed a haplotypic association of alcohol dependence with the gene encoding the {alpha}2 subunit of the {gamma}-aminobutyric acid type A (GABAA) receptor (GABRA2). The present study examined whether variation of the GABRA2 gene confers susceptibility to different subtypes of alcohol dependence in the German population. Methods: A total of 257 German alcohol-dependent patients and 88 healthy population controls were genotyped for six single-nucleotide polymorphisms covering the middle part and the 3′ end of GABRA2. Allelic, genotypic and haplotypic comparisons were done for subgroups of alcohol-dependent patients with a presumed high genetic load. Results:…

AdultMalemedicine.medical_specialtyGenotypeGene DosagePolymerase Chain ReactionPolymorphism Single NucleotideGastroenterologyLinkage DisequilibriumGABRG1Internal medicineGeneticsmedicineGenetic predispositionHumansGABRA2AlleleAllelesBiological PsychiatryGenetics (clinical)GeneticsbiologyHaplotypeAlcohol dependenceOdds ratioReceptors GABA-AGenetic loadAlcoholismPsychiatry and Mental healthHaplotypesCase-Control Studiesbiology.proteinFemalePsychiatric Genetics
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Urinary glycosaminoglycans in Graves' ophthalmopathy.

1990

An increased accumulation of glycosaminoglycans (GAG) in retrobulbar tissues has been reported in patients with thyroid eye disease. We examined the quantitative urinary GAG excretion in 101 patients with Graves' ophthalmopathy of different classes, 36 patients with Graves' hyperthyroidism without ophthalmopathy, 14 patients with toxic nodular goitre and 103 control subjects. Glycosaminoglycans were isolated from 24-h urine collections by precipitation with cetylpyridinium chloride and ethanol followed by photometrical quantification of hexuronic acids after reaction with carbazole. In comparison with the control group (15.8, 10.4, 21.6 mg/24 h; median, 25th, 75th percentile) a significant …

AdultMalemedicine.medical_specialtyGoiterAdolescentEndocrinology Diabetes and MetabolismGraves' diseaseUrinary systemUrineGraves' ophthalmopathyExcretionEndocrinologyInternal medicineImmunopathologymedicineHumansAgedGlycosaminoglycansAged 80 and overbusiness.industryThyroidMiddle Agedmedicine.diseaseCombined Modality TherapyGraves DiseaseEndocrinologymedicine.anatomical_structurePrednisoneFemalebusinessGoiter NodularClinical endocrinology
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Safety and efficacy of an intra-oral electrostimulator for the relief of dry mouth in patients with chronic graft versus host disease: case Series

2013

Objectives: Patients with chronic graft-versus-host disease (cGVHD) often suffer from dry mouth and oral mucosal lesions. The primary objective of this study was to investigate the safety of an intra-oral electrostimulator (GenNarino) in symptomatic cGVHD patients. The secondary objective was to study the impact on the salivary gland involvement of cGVHD patients. Study Design: This paper presents a case series. The study included patients treated for 4 weeks, randomly assigned to the active device and then crossed-over to a sham-device or vice versa. The patients and clinicians were blind to the treatment delivered. Data regarding oral mucosal and salivary gland involvement were collected.…

AdultMalemedicine.medical_specialtyGraft vs Host DiseaseElectric Stimulation TherapyOdontologíaDiseaseXerostomiaSalivary Glandslaw.inventionDouble-Blind MethodRandomized controlled triallawInternal medicinehemic and lymphatic diseasesmedicineHumansIn patientGeneral DentistryAgedOral Medicine and PathologySalivary glandbusiness.industryResearchMucosal lesionsEquipment DesignMiddle Agedmedicine.diseaseDry mouth:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryTreatment Outcomemedicine.anatomical_structureGraft-versus-host diseaseOtorhinolaryngologyIntra oralUNESCO::CIENCIAS MÉDICASFemaleSurgerymedicine.symptombusiness
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Oral potentially malignant disorders : clinical-pathological study of 684 cases diagnosed in a Brazilian population

2019

Background The frequency and distribution of oral potentially malignant disorders (OPMD) may vary among different populations. The aim of the present study was to evaluate the clinical-pathological characteristics of OPMD diagnosed in a Brazilian oral pathology laboratory over a period of 11 years. Material and Methods All cases diagnosed as leukoplakia, speckled leukoplakia, erythroplakia, and actinic cheilitis from 2005 to 2015 were analyzed. Clinical information was obtained from laboratory forms and histological information was obtained from histological slides stained with hematoxylin and eosin. Results the final sample was comprised of 684 cases, of which 292 were males and 392 were f…

AdultMalemedicine.medical_specialtyH&E stain03 medical and health sciences0302 clinical medicinestomatognathic systemTongueOral and maxillofacial pathologymedicineHumansGeneral DentistryLeukoplakiaAgedMouth neoplasmAged 80 and overErythroplakiaOral Medicine and Pathologybusiness.industryActinic cheilitisResearchMouth Mucosa030206 dentistryMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Dermatologystomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyDysplasiaErythroplasiaUNESCO::CIENCIAS MÉDICASSurgeryFemaleMouth NeoplasmsLeukoplakia OralbusinessPrecancerous ConditionsBrazil
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