Search results for "OSA"

showing 10 items of 9388 documents

Effect of epidural anesthesia on colorectal anastomosis: a tonometric assessment.

1997

PURPOSE: Epidural anesthesia is believed to benefit colorectal anastomotic blood flow because of the sympathetic blockade it produces. Our purpose is to measure with tonometry the effect of epidural anesthesia on colorectal anastomotic oxygenation. PATIENTS AND METHODS: Fifteen patients operated on for rectal cancer (radical anterior resection) were monitored postoperatively using tonometers placed in the stomach (celiac trunk), transverse colon (superior mesenteric artery), and the anastomotic area during the operation. An epidural catheter was placed at L1-2, and on the first postoperative day, 8 ml of bupivacaine (0.25 percent) was administered. The anesthetic effect extended up to T-4. …

AdultAnesthesia EpiduralMalemedicine.medical_specialtyColonRectumAnastomosisIntestinal mucosamedicine.arterymedicineHumansSuperior mesenteric arteryIntestinal MucosaAgedBupivacainePain Postoperativebusiness.industryStomachAnastomosis SurgicalGastroenterologyTransverse colonRectumGeneral MedicineHydrogen-Ion ConcentrationMiddle AgedBupivacaineColorectal surgerySurgeryOxygenmedicine.anatomical_structureGastric MucosaRegional Blood FlowAnesthesiaFemalebusinessColorectal Neoplasmsmedicine.drugDiseases of the colon and rectum
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Relationship between eating styles and temperament in an Anorexia Nervosa, Healtlhy Control, and Morbid Obesity female sample.

2014

Contains fulltext : 127209.pdf (Publisher’s version ) (Closed access) Objectives: Eating styles have been studied in both Obesity (OB) and Eating Disorders (ED), but they have not been examined in these two weight conditions together. The present study explores differences in eating styles in an Anorexia Nervosa (AN) and OB sample, compared to Healthy Controls (HC), and it analyses their relationship with Body Mass Index (BMI) and personality traits. Method: The total sample consisted of 291 female participants (66 AN, 79 OB and 146 HC). Evaluation: Assessment measures included the Dutch Eating Behaviour Questionnaire-DEBQ- and the Temperament and Character Inventory-Revised-TCI-R-. Results…

AdultAnorexia NervosaAdolescentPersonality Inventorymedia_common.quotation_subjectAnorexiaBody Mass IndexDevelopmental psychologyExperimental Psychopathology and TreatmentYoung AdultDiscriminant function analysisSurveys and QuestionnairesmedicineHumansBig Five personality traitsTemperamentGeneral Psychologymedia_commonNutrition and DieteticsBody Weightdigestive oral and skin physiologyFeeding BehaviorSDG 10 - Reduced InequalitiesMiddle AgedEmotional eatingmedicine.diseaseObesityHealthy VolunteersObesity MorbidEating disordersCross-Sectional Studies/dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalitiesFemaleTemperamentmedicine.symptomPsychologyBody mass index
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Are individuals with an eating disorder less sensitive to aesthetic flaws than healthy controls?

2008

Abstract Objective This study aimed to investigate whether the positive evaluation of other people's bodies is due to difficulties in the recognition of flaws in attractive features of others. Method Thirty female individuals with an eating disorder (IEDs) and 30 normal controls (NCs) rated pictures of a woman's face in relation to various manipulated facial features. Accuracy rates, discrepancy scores, and response times were assessed. Participants also answered questionnaires relating to social comparison, internalization of the slender ideal, and eating disorder symptoms. Results NCs were significantly more accurate at detecting flaws and recognized the degree of manipulation better than…

AdultAnorexia NervosaPersonality InventoryPersonal SatisfactionAnorexia nervosaDevelopmental psychologyFeeding and Eating DisordersBeautyInterpersonal relationshipSocial DesirabilityThinnessQuality of lifeSurveys and QuestionnairesBody ImagemedicineHumansInterpersonal RelationsObesityBulimia NervosaDriveSocial comparison theorySocial perceptionBulimia nervosaPhysiognomymedicine.diseaseControl GroupsPsychiatry and Mental healthClinical PsychologyEating disordersSocial PerceptionQuality of LifeFemalePersonality Assessment InventoryCognition DisordersPsychologyJournal of Psychosomatic Research
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Influence of appearance-related TV commercials on body image state.

2008

This study investigates the influence of media exposure on body image state in eating-disordered (ED) patients. The attitudinal and perceptual components of body image are assessed, as well as any associations with dysfunctional cognitions and behavioral consequences. Twenty-five ED patients and 25 non-ED controls (ND) viewed commercials either featuring appearance (AC; 5 min) or not featuring appearance (NC; 5 min). Both perceptual and attitudinal body image components changed markedly after the AC condition for ED patients, compared with the ND group and NC condition. Cognitions referring to dietary restraint and internalization/social comparison also changed significantly in ED patients…

AdultAnorexia Nervosamedia_common.quotation_subjectDysfunctional familyStimulus (physiology)Developmental psychologyBody Mass IndexCognitionArts and Humanities (miscellaneous)Social DesirabilityAdvertisingPerceptionDevelopmental and Educational PsychologymedicineBody ImageHumansBulimia NervosaSocial BehaviorSomatoform Disordersmedia_commonSocial comparison theoryDepressive DisorderCognitive Behavioral TherapyCognitive disorderCognitionmedicine.diseaseCognitive biasSelf ConceptClinical PsychologyEating disordersPhobic DisordersFemaleTelevisionPsychologyBehavior modification
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Mutational analysis of 105 mucopolysaccharidosis type VI patients

2007

Mucopolysaccharidosis type VI (MPS VI; Maroteaux-Lamy syndrome) is a lysosomal storage disorder caused by mutations in the N-acetylgalactosamine-4-sulfatase (arylsulfatase B, ARSB) gene. ARSB is a lysosomal enzyme involved in the degradation of the glycosaminoglycans (GAG) dermatan and chondroitin sulfate. ARSB mutations reduce enzyme function and GAG degradation, causing lysosomal storage and urinary excretion of these partially degraded substrates. Disease onset and rate of progression is variable, producing a spectrum of clinical presentation. In this study, 105 MPS VI patients—representing about 10% of the world MPS VI population—were studied for molecular genetic and biochemical parame…

AdultArylsulfatase BAdolescentN-Acetylgalactosamine-4-SulfataseMPS VIDNA Mutational AnalysisNonsense mutationMucopolysaccharidosis type VIBiologyPolymorphism Single NucleotideGenetic HeterogeneityAge DistributionGene FrequencyGenotypeGeneticsmedicineHumansMissense mutationGenetic TestingChildCells CulturedGenetics (clinical)mucopolysaccharidosis type VIGlycosaminoglycansGeneticsMucopolysaccharidosis VIGenetic heterogeneityMucopolysaccharidosis VIMiddle Agedmedicine.diseasearylsulfatase BMaroteaux–Lamy syndromeDisease ProgressionARSBMaroteaux-LamyHuman Mutation
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Circulating Betatrophin Levels Are Increased in Anorexia and Decreased in Morbidly Obese Women.

2015

Betatrophin is produced primarily by liver and adipose tissue and has been recently reported as a novel hormone promoting β-cell proliferation and β-cell mass and improving glucose tolerance.Because it is markedly regulated by nutritional status, we hypothesized that circulating betatrophin levels might be affected by pathophysiological conditions altering body weight.We analyzed circulating betatrophin levels in 149 female patients, including 99 with extreme body mass index (30 anorexia nervosa, 24 obese, 45 morbid obese, and 50 healthy eating/weight controls).Serum betatrophin levels and its correlations with different anthropometric and biochemical parameters were measured.Plasma betatro…

AdultBlood GlucoseLeptinmedicine.medical_specialtyAnorexia NervosaAdolescentBetatrophinEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPeptide HormonesClinical BiochemistryAdipose tissueContext (language use)AnorexiaAnorexia nervosaBiochemistryYoung AdultEndocrinologyAngiopoietin-Like Protein 8Internal medicineMedicineHumansInsulinbusiness.industryInsulinBiochemistry (medical)Middle Agedmedicine.diseaseObesityObesity MorbidEndocrinologyAngiopoietin-like ProteinsFemalemedicine.symptomInsulin ResistancebusinessBody mass indexThe Journal of clinical endocrinology and metabolism
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Determination of salivary glucose in healthy adults

2009

Podeu consultar la versió en castellà a: http://hdl.handle.net/2445/54584

AdultBlood GlucoseMalemedicine.medical_specialtySalivaDiagnòsticInternal medicineDiagnosismedicineHumansWhole salivaSalivaGeneral Dentistrybusiness.industrySignificant difference:CIENCIAS MÉDICAS [UNESCO]Spearman Correlation TestEndocrinologySalivary glucoseGlucoseOtorhinolaryngologyHealthy individualsGlucosaUNESCO::CIENCIAS MÉDICASSurgeryFemalebusiness
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Static and dynamic body image in bulimia nervosa: mental representation of body dimensions and biological motion patterns.

2006

The aim of the present study was to find out whether in bulimia nervosa the perceptual component of a disturbed body image is restricted to the overestimation of one's own body dimensions (static body image) or can be extended to a misperception of one's own motion patterns (dynamic body image).Participants with bulimia nervosa (n = 30) and normal controls (n = 55) estimated their body dimensions by means of a photo distortion technique and their walking patterns using a biological motion distortion device.Not only did participants with bulimia nervosa overestimate their own body dimensions, but also they perceived their own motion patterns corresponding to a higher BMI than did controls. S…

AdultBulimia nervosamedia_common.quotation_subjectMotion PerceptionBody movementmedicine.diseaseMotion (physics)Self ConceptDevelopmental psychologyPsychiatry and Mental healthDistortionPerceptionSurveys and QuestionnairesmedicineMental representationBody ImageHumansComputer SimulationFemaleMotion perceptionPsychologyBulimia Nervosamedia_commonBiological motionCognitive psychologyThe International journal of eating disorders
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The transcription factor IFN regulatory factor–4 controls experimental colitis in mice via T cell–derived IL-6

2008

The proinflammatory cytokine IL-6 seems to have an important role in the intestinal inflammation that characterizes inflammatory bowel diseases (IBDs) such as Crohn disease and ulcerative colitis. However, little is known about the molecular mechanisms regulating IL-6 production in IBD. Here, we assessed the role of the transcriptional regulator IFN regulatory factor-4 (IRF4) in this process. Patients with either Crohn disease or ulcerative colitis exhibited increased IRF4 expression in lamina propria CD3+ T cells as compared with control patients. Consistent with IRF4 having a regulatory function in T cells, in a mouse model of IBD whereby colitis is induced in RAG-deficient mice by transp…

AdultCD4-Positive T-LymphocytesMaleAdoptive cell transferRecombinant Fusion ProteinsT-LymphocytesCD3T cellAdoptive Transfer; Adult; Animals; Apoptosis; CD4-Positive T-Lymphocytes; Colitis; Cytokines; DNA-Binding Proteins; Female; Gene Expression Regulation; Humans; Inflammatory Bowel Diseases; Interferon Regulatory Factors; Interleukin-6; Intestinal Mucosa; Male; Mice; Mice Inbred C57BL; Mice Knockout; Middle Aged; Oxazolone; Receptors Interleukin-6; Recombinant Fusion Proteins; T-Lymphocytes; Trinitrobenzenesulfonic AcidApoptosisProinflammatory cytokineMiceIntestinal mucosamedicineAnimalsHumansIntestinal MucosaColitisInterleukin 6Mice KnockoutbiologyInterleukin-6OxazoloneGeneral MedicineMiddle AgedColitisInflammatory Bowel Diseasesmedicine.diseaseAdoptive TransferReceptors Interleukin-6Ulcerative colitisDNA-Binding ProteinsMice Inbred C57BLmedicine.anatomical_structureGene Expression RegulationTrinitrobenzenesulfonic AcidInterferon Regulatory FactorsImmunologybiology.proteinCytokinesFemaleResearch ArticleJournal of Clinical Investigation
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Retinoblastoma epidemiology: Does the evidence matter?

2007

It has been proposed that retinoblastoma is 'caused' by two sequential mutations affecting the RB1 gene, but this is a rather outdated view of cancer aetiology that does not take into account a large amount of new acquisitions such as chromosomal and epigenetic alterations. Retinoblastoma remains probably the only cancer in which the rather simplistic 'two hit' mutational model is still considered of value, although cancer is known to be associated with genomic and microsatellite instability, defects of the DNA mismatch repair system, alterations of DNA methylation and hystone acethylation/deacethylation, and aneuploidy. Moreover, as it is shown herein, the predictions made by the 'two hit'…

AdultCancer ResearchAdolescentRetinal NeoplasmsRetinoblastoma Aneuploidy Two hit theoryDiseaseBiologyAge DistributionChromosome instabilitymedicineHumansEpigeneticsAge of OnsetChildGerm-Line MutationGeneticsRetinoblastomaRetinoblastomaMicrosatellite instabilityCancerInfantMiddle Agedmedicine.diseasePedigreeSettore BIO/18 - GeneticaOncologyChild PreschoolDNA methylationDNA mismatch repair
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