Search results for "OSA"
showing 10 items of 9388 documents
Ohjauksen kirjaaminen : tyypin 2 diabetespotilaiden omahoito ja osaaminen potilasasiakirjoissa
2017
The purpose of this study was to describe the contents of type 2 diabetes patient self-management counselling documentation, how counselling of self- management appeared in various content areas and how patients’ self- management competence developed during the counselling. The research data consisted of nurses’ documentations from type 2 diabetes patient self- management counselling situations (N = 60) in primary health care. The data was collected in 2014 from the period between the years 2005 and 2014. Data were analyzed using content analysis as well as a case study approach. The documentation of self-management counselling included entries from content areas on nutrition, exercise, wei…
Aetosaur pes from the Upper Triassic of Krasiejów (Poland), with remarks on taxonomy of isolated bones
2021
The incomplete, articulated, right pes of an aetosaur, extracted from the lower bone-bearing horizon of the Krasiejów Late Triassic site, is larger than any other, known from among the Aetosauria. Its individual bones resemble those of at least three genera: Desmatosuchus (astragalus), Typothorax (ungual phalanges), and Stagonolepis (metatarsals). This underscores the highly speculative nature of the taxonomical classification of isolated postcranial bones and makes it impossible to assign the limb to any particular genus. The phalangeal formula is 2-3-4-5-?; for the fifth finger: 2/3/4 is possible. The anatomy of the pes indicates adaptation for digging.
“This Is the Future of Advertising!” Or Is It? New Insights into the Justifiability of Deceptive Crowdwork in Cyberspace
2022
Unlike classical forms of deception where the deceiver deceives their victims directly, the crowdsourcing of cyber deception provides a powerful and cost-effective mechanism for deceivers to create and spread falsehood from the shadows. But for a mass deception campaign to be effective, the crowdworkers must rationalize (and willingly accept) their role in the deceptive act. What, then, could justify participation in a mass-deception campaign? To answer this question, we adopt the qualitative vignette approach and utilize neutralization theory as our guiding lens. Our results point to several neutralization techniques that crowdworkers could invoke to convincingly rationalize involvement in…
Osallistumisen lupaus ja petos hyvinvointipalveluissa
2017
Artikkelissa analysoidaan osallistumisparadigmaa hyvinvointipalveluissa. Teoreettisen analyysin empiirisenä kaikupohjana ovat kirjoittajan osallistumistutkimukset sekä kansalliset ja kansainväliset osallistumisohjelmat. Analyysin välineenä sovellan kriittisen teorian traditioon kuuluvaa, Max Horkheimerin ja Theodor Adornon luomaa valistuksen dialektiikan käsitettä. Siihen sisältyy sekä valistuksen lupaus että petos. Osallistumiseen hyvinvointipalveluissa kytkeytyy lupaus demokratisoitumisesta, palvelujen paranemisesta ja kuulluksi tulemisen kokemuksesta. Osallistumisen lupaukset voivat kuitenkin kääntyä petokseksi, jos palvelujärjestelmä valjastaa osallistumisparadigman esime…
Herbicidal activity of phosphonic, phosphinic, and phosphonous acid analogues of phenylglycine and phenylalanine
1995
A series of phosphonic, phosphinic, and phosphonous acid analogues of phenylglycine and phenylalanine was synthesized and tested as herbicides against Lepidium sativum and Cucumis sativus. Aminobenzylphosphonic acids exhibited notable herbicidal activity and thus represent a group of the most active herbicides found among aminophosphonic acids.
Folate-targeted gold nanorods for effective combined photothermal-chemotherapy of osteosarcoma
2016
Osteosarcoma (OS) is the most common primary malignant neoplasm of bone. The annual incidence of osteosarcoma is 8-11 per million in the age group of 15-19 years. Despite its rarity, it has been reported to be the second leading cause of cancer-related deaths in children and young adults. In particular with regard to OS therapy, a variety of nanostructures have been exploited in the areas of OS imaging. Among them, Gold nanorods (AuNRs) have unique optical and chemical-physical properties that make them appealing for biomedical applications such as photothermal therapy, drug delivery and imaging of solid tumors. The noble metal core is biologically inert, contributing to low toxicity and go…
NIR LASER-RESPONSIVE FOLATE-TARGETED GOLD NANORODS AS EFFICIENT THERANOSTIC TOOL FOR OSTEOSARCOMA TREATMENT
2017
Folate-targeted gold nanorods (GNRs) are here proposed as selective theranostic agents for osteosarcoma treatment. Taking advantage of the attractive physiochemical and optical properties of GNRs they can be proposed as effective and selective platform to obtain a targeted intracellular drug release, photothermal therapy and cancer imaging, which may improve therapeutic outcomes of osteosarcoma. An amphiphilic polysaccharide graft-copolymer, named INU-LA-PEG-FA, and a folic acid functionalized α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide (PHEA-FA), have been synthesized to act as coating agents for GNRs. The obtained polymer-coated GNRs were characterized in terms of size, shape, zeta potenti…
Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia
2022
Drug resistance is the ability of cancer cells to gain resistance to both conventional and novel chemotherapy agents, and remains a major problem in cancer therapy. Resistance mechanisms are multifactorial and involve more strictly pharmacological factors, such as P-glycoprotein (P-gp) and biological factors such as inhibitor of apoptosis proteins (IAPs) and the nuclear factor-kappa B (NF-κB) pathway. Possible therapeutic strategies for the treatment of acute myeloid leukemia (AML) have increased in recent years; however, drug resistance remains a problem for most pa-tients. Phytol and heptacosane are the major compounds of Euphorbia intisy essential oil (EO) which were demonstrated to inhi…
Stato sanitario e micorrizazione in specie arboree forestali: casi studio in Italia
2016
La sanità delle piante è notoriamente correlata a elevati livelli di micorrizazione, soprattutto in ospiti strettamente dipendenti dalla simbiosi. Eventuali fattori di stress, abiotici o biotici, agenti di deperimento alterano il bilancio fotosintetico e influenzano, spesso negativamente, l’associazione mutualistica, aggravando così lo stato di sofferenza delle piante. Relativamente alle piante forestali, diversi studi hanno confermato l’intima interazione tra stato sanitario e micorrizazione. In questa nota si riportano i risultati di nostre indagini, condotte in due Regioni ecologicamente molto diverse, Lazio e Sicilia, rilevando lo stato micorrizico di piante di Fagus sp., Pinus sp. e Qu…
Metabolites from Mediterranean plant: characterization and trasformation. chemotaxonomic assessmentand biological activity
2016
Questo progetto di ricerca ha lo scopo di ampliare le conoscenze di alcune piante appartenenti alla flora Mediterranea. Le piante da studiare sono state scelte in seguito ad un’attenta analisi bibliografica tra specie poco sudiate. La scelta è quindi ricaduta su nove specie appartenenti al genere Anthemis, due specie appartenenti al genere Pulicaria e sulle specie di Tetraclinis articulata, Salvia argentea, Ajuga tenorei, Ballota hispanica, Moluccella Spinosa e Thapsia garganica. Di esse sono stati preparati ed identificati i componenti degli oli essenziali e successivamente effettuati su di essi i saggi antibatterici. Dagli estratti delle specie di Tetraclinis articulata e Ajuga tenorei so…