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Percepción del entorno deportivo juvenil por deportistas, padres, entrenadores y gestores

2021

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Desarrollo de la «Guía de consenso para el uso de medicamentos en insuficiencia renal»☆

2017

Artemisinin–Second Career as Anticancer Drug?

2015

Artemisinin represents a showcase example not only for the activity of medicinal herbs deriving from traditional chinese medicine, but for phytotherapy in general. Its isolation from Sweet Wormwood (qinhao, Artemisia annua L.) represents the starting point for an unprecedent success story in the treatment of malaria worldwide. Beyond the therapeutic value against Plasmodium parasites, it turned out in recent years that the bioactivity of artemisinin is not restricted to malaria. We and others found that this sesquiterpenoid also exerts profound anticancer activity in vitro and in vivo. Artemisinin-type drugs exert multi-factorial cellular and molecular actions in cancer cells. Ferrous iron …

Risk of Periodontal Disease: Is there a Correlation with the Type of Antihypertensive Medication?

2011

Introduction: The purpose of this study was to evaluate the effects of long-term oral antihypertensive treatment using centrally acting sympatho-inhibitory drugs (clonidine) and beta-blockers (metoprolol) on capillary microcirculation in the labial and periodontal mucosa.
 Methods: Sixty subjects were recruited for the study: 20 patients affected by hypertension in treatment with centrally-acting sympatho-inhibitory drugs (64.28 ± 11.78 years); 20 patients in treatment with beta-blockers (62.03 ± 9.84 years) and 20 healthy subjects (62.06 ± 6.72 years). We use the videocapillaroscopic technique to evaluate in vivo the microcirculation of the labial mucosa corresponding to the lower lip…

Loss Aversion and Risk Aversion in Non-Clinical Negative Symptoms and Hypomania

2020

In the field of behavioral decision-making, “loss aversion” is a behavioral phenomenon in which individuals show a higher sensitivity to potential losses than to gains. Conversely, “risk averse” individuals have an enhanced sensitivity/aversion to options with uncertain consequences. Here we examine whether hypomania or negative symptoms predict the degree of these choice biases. We chose to study these two symptom dimensions because they present a common theme across many syndromes with compromised decision-making. In our exploratory study, we employed a non-clinical sample to dissociate the hypomanic from negative symptom dimension regarding choice behavior. We randomly selected a sample …

On the Prevalence of Addicted or Problematic Gaming in Finland

2019

Highlights • A dataset from Finland in 2015 (systematic random sampling N = 4511) suggests an (unweighted) prevalence rate of certain “addicted gaming” (videogame play) to be 0.6% among local gamers and 0.03% among the whole population. • The implied prevalence of certain “problematic gaming” (videogame play) climbs to 1.4% among local gamers and 0.6% among the whole population. • Of those “addicted” individuals to whom videogame play was a problem “almost always,” eight reported their hours of play during a week (72, 30, 10, 7, 4, 1, 1, 1), which indicate that “addicted gaming,” if understood as excessive play, might not be optimal for describing such problems.

El sexo, el contexto familiar y la actividad física extraescolar como factores asociados a la coordinación motriz en la niñez. Un estudio piloto. [Ge…

2019

Existen diversos factores que determinan el desarrollo y la evolución de la coordinación motriz. El presente estudio tiene por objetivo analizar la influencia del sexo, la actividad física practicada por los padres, la existencia de hermanos/as mayores o de igual edad y la práctica de actividad física extraescolar sobre el nivel de coordinación motriz global. La muestra estuvo compuesta por 23 niñas y 32 niños de entre 8-9 años (M = 8,51; DT = 0,31), pertenecientes al tercer curso de Educación Primaria. El nivel de coordinación motriz global de los estudiantes se valoró a través del Test Motor GRAMI-2 (Ruiz, Rioja, Graupera, Palomo, y García, 2015). El análisis de regresión lineal múltiple …

Continuous Improvement on Detailed Design Phase : A Process Perspective

2020

The construction project being studied is a government investment related to the relocation of a biomedical institute delivering research-based knowledge and contingency support in the fields of animal health, fish health and food safety. The project covers a total of 63,000 square meters distributed over 10 buildings with a very high degree of complexity. The design alone has required 1 million hours, which relates to a client cost of about 100 million Euro. The purpose of this paper is to study the applied methodology for managing the detailed design to identify lessons learned from the project. The theory underlying the study is inspired by lean design management and design theory linked…

Optimizing artificial neural networks for the evaluation of asphalt pavement structural performance

2019

Artificial Neural Networks represent useful tools for several engineering issues. Although they were adopted in several pavement-engineering problems for performance evaluation, their application on pavement structural performance evaluation appears to be remarkable. It is conceivable that defining a proper Artificial Neural Network for estimating structural performance in asphalt pavements from measurements performed through quick and economic surveys produces significant savings for road agencies and improves maintenance planning. However, the architecture of such an Artificial Neural Network must be optimised, to improve the final accuracy and provide a reliable technique for enriching d…

Caracterización de barita cubana y su reducción carbotérmica en horno de microondas

2007

The Cuban Barite (BaSO<sub>4</sub>) is characterized by X ray diffraction, chemical analysis and scanning electron microscopy. The principal components are identified and its characteristic morphology is shown. Its carbothermic reduction under microwave irradiation is carried out with the purpose of to improve the yield of this stage during the mineral transformation process in reagent of barium of diverse applications.<br><br>La barita cubana (BaSO<sub>4</sub>) se ha caracterizado por difracción de rayos X, análisis químico y microscopía electrónica de barrido. Se han identificado sus componentes mayoritarios y así mismo se muestra su morfología caracter…