Search results for "OTR"

showing 10 items of 6791 documents

Antral follicle count (AFC) can be used in the prediction of ovarian response but cannot predict the oocyte/embryo quality or the in vitro fertilizat…

2007

To verify whether the antral follicle count (AFC) could predict ovarian response, oocyte/embryo quality, and IVF outcome.Prospective study.Instituto Universitario-Instituto Valenciano de Infertilidad, Valencia, Spain.One thousand seventy-four donors and 975 oocyte recipient cycles.Controlled ovarian hyperstimulation (COH), endometrial preparation, IVF/intracytoplasmic sperm injection, ET.COH and oocyte/embryo quality parameters and IVF outcome.We observed lower E(2) levels and fewer mature retrieved oocyte numbers among donors who showed an AFC that was10. These donors also showed significantly higher cancellation and no-donation rates; poor and/or insufficient response was the principal ca…

Adultmedicine.medical_specialtymedicine.medical_treatmentEmbryonic DevelopmentOocyte RetrievalCell CountFertilization in VitroControlled ovarian hyperstimulationIntracytoplasmic sperm injectionAndrologyYoung AdultEgg donationOvarian FollicleEmbryo cryopreservationPredictive Value of TestsPregnancymedicineHumansUltrasonographyGynecologyIn vitro fertilisationOocyte Donationbusiness.industryPatient SelectionOvaryPregnancy OutcomeObstetrics and GynecologyFertility Agents FemaleEmbryo MammalianAntral follicleEmbryo transferReproductive MedicineSpainFertilizationVaginaembryonic structuresOocytesFemaleLeuprolidebusinessGonadotropinsEmbryo qualityFertility and Sterility
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Electromagnetically generated extracorporeal shockwaves for fragmentation of extra-and intrahepatic bile duct stones: indications, success and proble…

1990

Electromagnetically generated extracorporeal shock waves (without waterbath) were applied after intravenous premedication with 10-15 mg diazepam and 100 mg tramadol in the treatment of 33 patients (aged 32 to 91 years) with multiple intrahepatic stones (n = 4) or huge common bile duct stones (n = 29, 18-30 mm in diameter), which could not be removed by conventional endoscopy. Stone disintegration was achieved in 70% of common bile duct stones and in all intrahepatic concrements after 800-7500 discharges, which were applied during one (n = 21), two (n = 6) or three sessions (n = 6). Apart from mild fleabite-like petechiae at the side of shock wave transmission no other side effects were obse…

Adultmedicine.medical_specialtymedicine.medical_treatmentIntrahepatic bile ductsBile Duct DiseasesGallstonesLithotripsyExtracorporealCholelithiasisLithotripsymedicineHumansAgedAged 80 and overCholangiopancreatography Endoscopic RetrogradeCommon bile ductmedicine.diagnostic_testbusiness.industryGastroenterologyGallstonesMiddle Agedmedicine.diseaseSurgeryEndoscopymedicine.anatomical_structureBile Ducts IntrahepaticBiliary tractFemaleBile Duct DiseasesbusinessElectromagnetic PhenomenaResearch Article
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Corticobulbar tract involvement in amyotrophic lateral sclerosis. A transcranial magnetic stimulation study

1998

We investigated corticobulbar tract function by recording from the tongue and orofacial muscles and using transcranial magnetic stimulation (TMS) in 30 patients with amyotrophic lateral sclerosis (ALS) in order to improve the diagnostic yield in the detection of subclinical upper motor neuron (UMN) dysfunction. A UMN lesion was assumed when the peripheral conduction time and amplitude of the M-wave were within normal range and either the response to cortical stimulation was absent, or the central conduction time was delayed (> mean + 2.5 SD). Only two patients showed clinical evidence of UMN involvement in the cranial nerves, while TMS demonstrated corticobulbar tract dysfunction in the oro…

Adultmedicine.medical_treatmentPyramidal TractsFacial MusclesCentral nervous system diseaseTongueTonguePhysical StimulationmedicineHumansAmyotrophic lateral sclerosisAgedSubclinical infectionMouthbusiness.industryUpper motor neuronAmyotrophic Lateral SclerosisCranial nervesAnatomyMiddle Agedmedicine.diseaseTranscranial Magnetic StimulationTranscranial magnetic stimulationmedicine.anatomical_structureCorticobulbar tractNeurology (clinical)businessBrain
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Laparoscopic management of interstitial pregnancy: the "purse-string" technique

2012

We report five cases of interstitial pregnancy, treated between 2004 and 2010, to evaluate surgical and obstetric outcome of laparoscopic cornual resection with a "purse-string" technique. A hemostatic suture was passed at the base of the mass in a purse-string fashion prior to resection, to minimize intraoperative blood loss. Subsequent pregnancies were analysed, with a mean follow-up time of 48 months. The mean operating time was 39 min and mean blood loss 47 mL. Three of four patients who desired children delivered at term uneventfully. Laparoscopic cornual resection with a "purse-string" technique appears to be useful for treatment of early interstitial pregnancy. The technique ensures …

Adultpurse-string techniqueSuture TechniquesFertility PreservationGestational AgeSettore MED/40 - Ginecologia E OstetriciaLaparoscopy interstitial pregnancy purse-string technique ectopic pregnancy hemostatic suture.hemostatic sutureSettore MED/18 - Chirurgia GeneraleTreatment OutcomePregnancyinterstitial pregnancyHumansectopic pregnancyChorionic Gonadotropin beta Subunit HumanFemalePregnancy TubalLaparoscopyBiomarkersFallopian Tubes
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Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission.…

2019

Abstract To assess the effectiveness of the treatment with high dosage of corticosteroids (CCSs), as first-line therapy, in inducing remission in naïve Adult-onset Still's disease (AOSD) patients compared with low dosage of CCSs, after 6 months. To further evaluate the rate of patients maintaining the remission and the rate of CCSs discontinuation, after additional 12 months of follow-up. A retrospective evaluation of patients prospectively followed was designed to compare the rate of clinical remission in naïve AOSD patients treated with high dosages of CCSs (0.8–1 mg/kg/day of prednisone-equivalent) or low dosage of CCSs (0.2–0.3 mg/kg/day of prednisone-equivalent), after 6 months. An add…

Adult-OnsetMalePediatricsAdult-onset Still's diseaseDiseaseAdrenal Cortex Hormonecorticosteroids0302 clinical medicinemonocyclic patternAdrenal Cortex HormonesRetrospective StudieMedicine030212 general & internal medicineProspective StudiesProspective cohort studyRemission InductionDisease ManagementGeneral MedicineMiddle AgedTreatment OutcomeHigh dosage030220 oncology & carcinogenesisFemaleDrugStill's Disease Adult-OnsetResearch ArticleHumanAdultcorticosteroidmedicine.medical_specialtyLow dosageObservational StudyAdult-onset Still's diseaseFollow-Up StudieDose-Response Relationship03 medical and health sciencesremissionAdult-onset Still's disease; corticosteroids; first-line therapy; monocyclic pattern; remission; Adrenal Cortex Hormones; Adult; Disease Management; Dose-Response Relationship Drug; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Retrospective Studies; Still's Disease Adult-Onset; Treatment Outcomefirst-line therapyHumansRetrospective StudiesDose-Response Relationship Drugbusiness.industry6900Retrospective cohort studyStill's DiseaseFirst line treatmentSettore MED/16 - ReumatologiaProspective StudieMethotrexateObservational studybusinessFollow-Up Studies
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Characterization of oligomeric compounds in secondary organic aerosol using liquid chromatography coupled to electrospray ionization Fourier transfor…

2009

The components of secondary organic aerosols (SOAs) generated from the gas-phase ozonolysis of two C(10)H(16)-terpenes (alpha-pinene; sabinene) and a cyclic C(6)H(10) alkene (cyclohexene) were characterized by the use of a Fourier transform ion cyclotron mass spectrometer equipped with an electrospray ionization source operated in the negative ion mode. Reversed-phase high-performance liquid chromatography was used to achieve chromatographic separation of highly oxidized organic compounds. In addition to the well-known group of low molecular weight oxidation products (monomers; e.g. dicarboxylic acids), higher molecular weight compounds (dimers) were also detected and their exact elemental …

AerosolsSpectrometry Mass Electrospray IonizationChromatographyChemistryElectrospray ionizationOrganic ChemistryAnalytical chemistryExtractive electrospray ionizationMass spectrometryTandem mass spectrometryFourier transform ion cyclotron resonanceIon sourceAnalytical ChemistryTandem Mass SpectrometryCyclohexenesSpectroscopy Fourier Transform InfraredMonoterpenesDirect electron ionization liquid chromatography–mass spectrometry interfaceChromatography High Pressure LiquidSpectroscopyBicyclic MonoterpenesAmbient ionizationRapid Communications in Mass Spectrometry
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On reliability of systems with moving material subjected to fracture and instability

2015

Abstract The reliability of systems with moving cracked elastic and isotropic material is considered. The material is modeled as a moving plate which continually has a crack on the edge. The plate is subjected to homogeneous tension acting in the traveling direction and the tension varies temporally around a constant value, the set tension. The tension and the length of the crack are modeled by an Ornstein–Uhlenbeck process and an exponential Ornstein–Uhlenbeck process, respectively. Failure is regarded as the state at which the plate becomes unstable or fractures (or both) and a lower bound for the reliability of the system is derived. Considering reliability of the system leads to first p…

Aerospace EngineeringBoundary (topology)Ocean EngineeringInstabilityOrnstein–Uhlenbeck processfirst passage timerandom parametersCivil and Structural EngineeringMathematicsta214Tension (physics)business.industryMechanical EngineeringIsotropyStatistical and Nonlinear PhysicsOrnstein–Uhlenbeck processStructural engineeringMechanicsstabilitymoving plateCondensed Matter PhysicsNuclear Energy and EngineeringfractureFracture (geology)First-hitting-time modelConstant (mathematics)businessProbabilistic Engineering Mechanics
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Stochastic analysis of the critical velocity of an axially moving cracked elastic plate

2014

In this study, a probabilistic analysis of the critical velocity for an axially moving cracked elastic and isotropic plate is presented. Axially moving materials are commonly used in modelling of manufacturing processes, like paper making and plastic forming. In such systems, the most serious threats to runnability are instability and material fracture, and finding the critical value of velocity is essential for efficiency. In this paper, a formula for the critical velocity is derived under constraints for the probabilities of instability and fracture. The significance of randomness in different model parameters is investigated for parameter ranges typical of paper material and paper machin…

Aerospace EngineeringOcean EngineeringInstabilityRandomnessCivil and Structural EngineeringPhysicsta113Tension (physics)business.industryMechanical EngineeringplateIsotropypaperiStatistical and Nonlinear PhysicsMechanicsStructural engineeringmoving materialstabilityCondensed Matter PhysicsCritical valueCritical ionization velocityepävarmuusNuclear Energy and EngineeringfractureFracture (geology)businessAxial symmetryProbabilistic engineering mechanics
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Unit study in cat claustrum of the effects of iontophoretic neurotransmitters and correlations with the effects of activation of some afferent pathwa…

1982

Glutamate (Glut), acetylcholine (ACh) and dopamine (DA) were iontophoretically applied on cat claustral neurons. Glut did not affect all the neurons; ACh had both excitatory and inhibitory effects, while DA was prevalently inhibitory. An analysis was made of the time-course of excitatory and inhibitory responses on the basis of the mean firing rate variations during and after ACh and DA release. Three types of responses are described for each drug: short lasting inhibition, long lasting inhibition and long lasting excitation. The experimental data were statistically elaborated. The effects of ACh and of DA were compared with those of activation obtained by sensorial peripheric and thalamic …

Afferent PathwaysNeurotransmitter AgentsIontophoresisPhysiologyChemistryDopamineGlutamate receptorIontophoresisInhibitory postsynaptic potentialBiochemistryClaustrumAcetylcholineBasal GangliaAcoustic StimulationDopamineAfferentCatsmedicineExcitatory postsynaptic potentialAnimalsNeuroscienceAcetylcholinemedicine.drugArchives Internationales de Physiologie et de Biochimie
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Cytogenetic effects of promutagens in genetically engineered V79 Chinese hamster cells expressing cytochromes P450.

1993

Abstract V79 Chinese hamster cell lines genetically engineered to express rat CYP2B1, CYP1A1, CYP1A2, and their parental cell lines V79-MZ, without acetyltransferase, and V79-NH, with acetyltransferase, were studied for chromosome aberrations and sister chromatid exchange induced by aflatoxin B 1 , cyclophosphamide, benzo[a]pyrene, 7,12-dimethylbenz[a]anthracene and dimethylnitrosamine. The parental V79 cell lines did not show clastogenic effects. Significant clastogenic effects were observed after an 18 h exposure to aflatoxin B 1 and cyclophosphamide in CYP2B1 expressing cells, to benzo[a]pyrene in CYP1A1 and CYP1A2 expressing cells, to 7,12-dimethylbenz[a]anthracene and dimethylnitrosami…

Aflatoxin B1910-Dimethyl-12-benzanthraceneHamsterSister chromatid exchangeMutagenToxicologymedicine.disease_causeChinese hamsterCell LineDimethylnitrosamineClastogenCricetulusCytochrome P-450 Enzyme SystemCricetinaepolycyclic compoundsmedicineBenzo(a)pyreneAnimalsCyclophosphamideBiotransformationPharmacologyChromosome Aberrationsbiologyrespiratory systembiology.organism_classificationPollutionMolecular biologyIn vitroRatsCell cultureAcetyltransferaseGenetic EngineeringSister Chromatid ExchangeMutagensEuropean journal of pharmacology
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