Search results for "OUTCOME"

showing 10 items of 5148 documents

Use of Marginal Donors in Kidney Transplantation: Our Experience

2006

The use of elderly donors has been advocated to expand the organ donor pool because of increased needs and the organ shortage. The aim of this study was to analyze whether the use of elderly donors and marginal kidneys affected the outcome of renal transplantations. Herein we presented data on 126 kidney transplantations performed from January 1996 to September 2003 using 32 marginal donors (group A) and 94 ideal donors (group B). We analyzed the medical and surgical complications and the graft survivals at a median follow-up of 18 months. Medical and surgical complications occurred in 22% and 5% versus 7% and 4% in groups A and B, respectively. The mean cold ischemia time and the mean age …

medicine.medical_specialtyTime FactorsWaiting ListsEconomic shortageelderly patientsCold Ischemia TimeGroup BPostoperative ComplicationsCadaverHumansMedicineDonor poolKidney transplantationMarginal donorRetrospective StudiesTransplantationKidneybusiness.industryGraft SurvivalMean agemedicine.diseaseKidney TransplantationTissue DonorsSurgeryTreatment Outcomemedicine.anatomical_structureItalySurgeryGraft survivalbusinessFollow-Up StudiesTransplantation Proceedings
researchProduct

Three-Year Results of Hydrus Microstent with Phacoemulsification

2019

Abstract We report the 3-year IOP efficacy of the implantation of the Schlemm’s canal Hydrus® Microstent (Ivantis®) combined with phacoemulsification versus phacoemulsification alone

medicine.medical_specialtyTime Factorsgenetic structuresmedicine.medical_treatmentGlaucoma01 natural sciencesCataract03 medical and health sciences0302 clinical medicineOphthalmologymedicineHumansSingle-Blind MethodProspective Studies0101 mathematicsGlaucoma Drainage ImplantsMiniaturizationPhacoemulsificationbusiness.industry010102 general mathematicsGlaucomaGeneral MedicinePhacoemulsificationmedicine.diseaseeye diseasesTreatment Outcome030221 ophthalmology & optometryStentssense organsbusinessFollow-Up Studies
researchProduct

A decade of trials of interferon-alpha for chronic hepatitis C. A meta-regression analysis

2003

The most relevant randomized controlled trials of interferon-alpha (IFN) for naive patients with chronic hepatitis C (CHC) published in a decade, just before appearance of pegylated IFN trials in 2000, were included in this paper. Its purpose is to review the relationship between sustained biochemical response in active versus control group versus usual clinical variables as IFN regimens, cirrhosis, genotype and versus less frequently addressed variables as funding, methodological quality or location of principal author. Meta-analysis estimates of global treatment effect varied according to trial design: group 1=IFN versus placebo/no treatment, 32 RCTs, 2499 pts, OR 9.5 (6.3-14.2); group 2a…

medicine.medical_specialtyTime FactorsinteractionAlpha interferonSubgroup analysisLogistic regressionPlaceborandom effects modellaw.inventionchemistry.chemical_compoundRandomized controlled triallawInternal medicinemeta-regressionmedicineHumansPharmacology (medical)Meta-regressionInterferon alfaRandomized Controlled Trials as Topicbusiness.industrylogistic regressionRibavirinInterferon-alphaGeneral MedicineHepatitis C ChronicLogistic ModelsTreatment OutcomechemistryImmunologyfixed effects modelbusinessmedicine.drugContemporary Clinical Trials
researchProduct

The effects of transdermal testosterone and oestrogen therapy on dry eye in postmenopausal women: a randomised, placebo-controlled, pilot study

2016

Aims Sex hormones could provide a future treatment avenue for dry eye post menopause. However, there are few well-controlled studies. This study investigates the impact of testosterone and oestrogen on dry eye symptoms and signs in postmenopausal women. Methods A randomised double-blind placebo-controlled pilot study was conducted involving 40 women with dry eye (age 63.9±5.1 years, 13.2±6.3 years post menopause). Ten women were assigned to each of four treatment groups: transdermal testosterone, oestradiol, testosterone/oestradiol combination and placebo. Assessment at baseline and after 8 weeks: ocular symptoms, tear osmolarity, tear stability, tear secretion, meibomian gland assessment, …

medicine.medical_specialtyTime Factorsmedicine.drug_classMeibomian glandPhysiologyPilot ProjectsAdministration CutaneousPlacebo03 medical and health sciencesCellular and Molecular Neurosciencechemistry.chemical_compound0302 clinical medicineDehydroepiandrosterone sulfateDouble-Blind MethodInternal medicineHumansMedicineTestosteroneTear secretionRetrospective Studies030219 obstetrics & reproductive medicinebusiness.industryMeibomian GlandsEstrogensTestosterone (patch)Middle AgedAndrogeneye diseasesSensory SystemsPostmenopauseOphthalmologyTreatment Outcomemedicine.anatomical_structureEndocrinologychemistryTearsAndrogens030221 ophthalmology & optometryTearsDry Eye SyndromesFemalesense organsbusinessFollow-Up StudiesHormoneBritish Journal of Ophthalmology
researchProduct

The use of a new kind of low profile retractor for arteriovenous fistula procedure simplifies and speeds up the intervention

2009

Purpose The aim of this study was to demonstrate the effectiveness of a new kind of disposable surgical retractor in arteriovenous fistula (AVF) procedures in order to achieve an easier, faster and safer surgical intervention. Methods Between January and June 2008, 22 AVF procedures were performed using the 3PAWS ReeTrakttrade; (Insightra Inc. - Irvine, Ca., USA) a self-retaining, low profile retractor. An equivalent patient sample, in which an AVF was performed using conventional retraction devices, was considered for comparison of the intra- and post-operative results. Results In all of the 22 AVF procedures performed, the ReeTrakt™ system has simplified the performance of the surgical te…

medicine.medical_specialtyTime Factorsmedicine.medical_treatment030232 urology & nephrologyArteriovenous fistulaarterioveunous fistula retractors030204 cardiovascular system & hematology03 medical and health sciencesArteriovenous Shunt Surgical0302 clinical medicineOperating timeHumansMedicinePatient groupDisposable EquipmentReduction (orthopedic surgery)Brachiocephalic VeinsRetrospective StudiesSurgical teamSurgical instrumentationSurgical Fixation Devicebusiness.industryEquipment DesignSurgical Instrumentsmedicine.diseasearteriovenous fistulaReeTrakt systemSurgeryRetractorForearmSettore MED/18 - Chirurgia GeneraleTreatment OutcomeNephrologyRadial ArterySurgerybusiness
researchProduct

Comparison of Percutaneous Coronary Intervention (With Drug-Eluting Stents) Versus Coronary Artery Bypass Grafting in Women With Severe Narrowing of …

2014

Women typically present with coronary artery disease later than men with more unfavorable clinical and anatomic characteristics. It is unknown whether differences exist in women undergoing treatment for unprotected left main coronary artery (ULMCA) disease. Our aim was to evaluate long-term clinical outcomes in women treated with percutaneous coronary intervention (PCI) with drug-eluting stents versus coronary artery bypass grafting (CABG). All consecutive women from the Drug-Eluting stent for LefT main coronary Artery disease registry with ULMCA disease were analyzed. A propensity matching was performed to adjust for baseline differences. In total, 817 women were included: 489 (59.8%) unde…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentCoronary AngiographySeverity of Illness IndexCoronary artery diseasePercutaneous Coronary InterventionRisk FactorsInternal medicinemedicineHumansMyocardial infarctionRegistriesCoronary Artery BypassPropensity ScoreAgedRetrospective Studiesbusiness.industryCoronary StenosisPercutaneous coronary interventionStentDrug-Eluting StentsOdds ratiomedicine.diseaseCoronary VesselsSurgerymedicine.anatomical_structureTreatment OutcomeDrug-eluting stentConventional PCICardiologyFemaleCardiology and Cardiovascular MedicinebusinessArteryFollow-Up Studies
researchProduct

Transverse Small Skin Incision for Carotid Endarterectomy

2015

The purpose of this report is to determine the feasibility of short transverse skin incision (STI4 cm) for eversion (EEA) and patch (PEA) endarterectomy with or without shunt by comparing it with the outcomes after long transverse skin incision (LTI 4-8 cm).Of 164 elective consecutive patients (71 ± 2.73% symptomatic) operated at one institution over 24 months, 81 were treated with STI, while 83 patients received LTI. The LTI and STI groups did not differ in terms of age, symptoms, or risk factors. EEA or PEA under locoregional (LRA) or general (GA) anesthesia were performed.STI was associated with shorter operation times (75.19 ± 15.33 vs. 94.87 ± 41 and 99.4 ± 27.36 vs. 132.66 ± 51.32, re…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentDermatologic Surgical ProceduresOperative TimeMedizinCarotid endarterectomyAnesthesia Generalurologic and male genital diseasesSeverity of Illness IndexCicatrixGermanyHumansMedicineCarotid StenosisParesthesiaEndarterectomy CarotidSkin incisionbusiness.industryGeneral Medicinefemale genital diseases and pregnancy complicationsSurgeryTreatment OutcomeFeasibility StudiesSurgeryCardiology and Cardiovascular MedicineComplicationbusinessAnesthesia LocalAnnals of Vascular Surgery
researchProduct

A score model for the continuous grading of early allograft dysfunction severity

2014

Early allograft dysfunction (EAD) dramatically influences graft and patient outcomes. A lack of consensus on an EAD definition hinders comparisons of liver transplant outcomes and management of recipients among and within centers. We sought to develop a model for the quantitative assessment of early allograft function [Model for Early Allograft Function Scoring (MEAF)] after transplantation. A retrospective study including 1026 consecutive liver transplants was performed for MEAF score development. Multivariate data analysis was used to select a small number of postoperative variables that adequately describe EAD. Then, the distribution of these variables was mathematically modeled to assig…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentLiver transplantationModels BiologicalSeverity of Illness IndexDecision Support TechniquesLiver diseasePredictive Value of TestsRisk FactorsInternal medicineSeverity of illnessmedicineHumansInternational Normalized RatioBlood CoagulationProportional Hazards ModelsRetrospective StudiesPrincipal Component AnalysisTransplantationHepatologyProportional hazards modelbusiness.industryGraft SurvivalReproducibility of ResultsAlanine TransaminaseBayes TheoremBilirubinRetrospective cohort studyClinical Enzyme Testsmedicine.diseaseLiver TransplantationSurgeryTransplantationTreatment OutcomeNonlinear DynamicsPredictive value of testsMultivariate AnalysisSurgeryLiver functionPrimary Graft DysfunctionbusinessBiomarkersLiver Transplantation
researchProduct

Nonroutine Use of Intra-Aortic Balloon Pump in Cardiogenic Shock Complicating Myocardial Infarction With Successful and Unsuccessful Primary Percutan…

2018

Abstract Objectives The authors sought to compare outcomes of patients with myocardial infarction and cardiogenic shock (CS) treated with percutaneous coronary intervention (PCI) with or without intra-aortic balloon pump (IABP) support according to final epicardial flow in the infarct-related artery. Background A routine use of IABP is contraindicated in patients with myocardial infarction and CS. There are no data regarding the subpopulation of patients who may benefit from such support besides patients with mechanical complications of myocardial infarction. Methods Prospective nationwide registry data of patients with myocardial infarction and CS treated with PCI between 2003 and 2014 wer…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentShock Cardiogenicprimary PCI030204 cardiovascular system & hematology03 medical and health sciencesPercutaneous Coronary Intervention0302 clinical medicineRisk FactorsInternal medicinemedicineHumansProspective StudiesRegistriescardiovascular diseases030212 general & internal medicineMyocardial infarctionIABPNon-ST Elevated Myocardial InfarctionIntra-aortic balloon pumpIntra-Aortic Balloon Pumpingbusiness.industryCardiogenic shockHazard ratiocardiogenic shockPercutaneous coronary interventionRecovery of FunctionThrombolysismedicine.diseaseTreatment Outcomesurgical procedures operativemyocardial infarctionConventional PCICardiologyST Elevation Myocardial InfarctionPolandCardiology and Cardiovascular MedicinebusinessTIMIJACC-Cardiovascular Interventions
researchProduct

Simultaneous cardiocerebral embolization in patients with atrial fibrillation

2020

medicine.medical_specialtyTime Factorsmedicine.medical_treatment[SDV]Life Sciences [q-bio]Myocardial Infarction030204 cardiovascular system & hematologyRisk AssessmentDecision Support Techniques03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineAtrial FibrillationIschaemic strokemedicineHumansThrombolytic TherapyIn patientMyocardial infarctionEmbolizationAngioplasty Balloon CoronaryIschemic StrokeThrombectomybusiness.industryAtrial fibrillationGeneral Medicinemedicine.diseaseCoronary embolismTreatment OutcomeIntracranial EmbolismConcomitantCardiologyStentsCardiology and Cardiovascular MedicinebusinessAlgorithms030217 neurology & neurosurgery
researchProduct