Search results for "OUTCOME"

showing 10 items of 5148 documents

Cementless acetabular reconstruction and structural bone-grafting in dysplastic hips. Surgical technique.

2007

BACKGROUND: Studies of acetabular reconstruction with use of cement and bulk bone graft have demonstrated increasing rates of cup failure in patients with dysplastic hips seven years after total hip arthroplasty. Comparable data on the long-term results of bulk bone-grafting done in conjunction with cementless implants are limited. The aim of this study was to review the clinical and radiographic results of autologous bulk bone-grafting in conjunction with a cementless cup. METHODS: From 1987 to 1992, forty-seven patients (forty women and seven men, with an average age of 50.4 years) who had developmental dysplasia of the hip underwent fifty-six total hip arthroplasties and received a struc…

musculoskeletal diseasesMaleReoperationmedicine.medical_specialtyRadiographymedicine.medical_treatmentBone graftingTransplantation AutologousArthroplastymedicineHip DislocationHumansOrthopedics and Sports MedicineProspective StudiesSurvival rateHip dysplasiaBone Transplantationbusiness.industryAcetabulumGeneral MedicineMiddle Agedmedicine.diseaseAcetabulumSurgeryProsthesis FailureTransplantationRadiographysurgical procedures operativeTreatment OutcomeOrthopedic surgerySurgeryFemaleImplantHip ProsthesisbusinessThe Journal of bone and joint surgery. American volume
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High frequency of lumbar fusion in patients denied surgical treatment of the sacroiliac joint.

2019

Purpose: Effective treatment of medical conditions relies on proper diagnosis. Clinical trials show the safety and effectiveness of sacroiliac joint (SIJ) fusion in patients with chronic SI joint dysfunction. To what extent is the condition under recognised? Objective: To determine whether under recognition of SIJ pain affects healthcare trajectories in Spanish patients with low back pain. Methods: Retrospective study of characteristics and consequences of 189 patients with persistent SIJ pain seen in an outpatient neurosurgery clinic. Results: Patients with SIJ pain who were denied surgical treatment had a longer pain duration, higher likelihood of prior lumbar fusion, and a high rate (63%…

musculoskeletal diseasesMalemedicine.medical_specialtyTime FactorsSacroiliac joint pain03 medical and health sciences0302 clinical medicineLumbarCirurgia operatòriamedicineEffective treatmentHumansIn patientSurgical treatmentRetrospective StudiesSacroiliac jointbusiness.industryLumbosacral RegionSacroiliac JointGeneral MedicineMiddle AgedLow back painArthralgiaSurgeryClinical trialmedicine.anatomical_structureSpinal FusionTreatment Outcome030220 oncology & carcinogenesisSurgeryFemaleNeurology (clinical)Lumbàlgiamedicine.symptomChronic PainbusinessLow Back Pain030217 neurology & neurosurgeryBritish journal of neurosurgery
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Muscle deficits persist after unilateral knee replacement and have implications for rehabilitation.

2009

BackgroundKnee joint arthritis causes pain, decreased range of motion, and mobility limitation. Knee replacement reduces pain effectively. However, people with knee replacement have decreases in muscle strength (“force-generating capacity”) of the involved leg and difficulties with walking and other physical activities.Objective and DesignThe aim of this cross-sectional study was to determine the extent of deficits in knee extensor and flexor muscle torque and power (ability to perform work over time) and in the extensor muscle cross-sectional area (CSA) after knee joint replacement. In addition, the association of lower-leg muscle deficits with mobility limitations was investigated.Methods…

musculoskeletal diseasesMalemedicine.medical_specialtymedicine.medical_treatmentKnee replacementArthritisPhysical Therapy Sports Therapy and RehabilitationOsteoarthritisMuscle Strength DynamometerKnee JointWeight-BearingPhysical medicine and rehabilitationmedicineHumansMuscle StrengthMobility LimitationRange of Motion ArticularArthroplasty Replacement KneeMuscle SkeletalAgedRehabilitationbusiness.industryWork (physics)Middle AgedOsteoarthritis Kneemusculoskeletal systemmedicine.diseasePreferred walking speedTreatment OutcomePhysical therapyFemaleRange of motionbusinesshuman activitiesMuscle ContractionPhysical therapy
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Preliminary Experience with a Novel System of Facet Fixation to Treat Patients with Lumbar Degenerative Disease. A New Perspective in Minimally Invas…

2017

Purpose We report our experience with a novel surgical device for the treatment of lumbar degenerative microinstability. Facet Wedge (DePuy Synthes, Raynham, Massachusetts, United States) is a novel technique of intra-articular lumbar facet fixation that provides a minimally invasive alternative to standard posterior fixation. Materials and Methods From November 2014 to July 2015, 38 patients underwent single-level Facet Wedge implantation. The main surgical indications included herniated disk (18 patients), spinal canal and foraminal stenosis (14 patients), and Meyerding grade I degenerative spondylolisthesis (6 patients). All the patients showed radiologic signs of microinstability: hype…

musculoskeletal diseasesMalemicroinstabilitymedicine.medical_specialtyfacet wedgedegenerative lumbar diseaseRadiographyIntervertebral Disc DegenerationZygapophyseal Joint03 medical and health sciencesFixation (surgical)0302 clinical medicineLumbarDegenerative diseasemedicineHumansMinimally Invasive Surgical ProceduresSpinal canal030212 general & internal medicineHerniated diskAgedLumbar Vertebraemedicine.diagnostic_testSettore MED/27 - Neurochirurgiabusiness.industryMagnetic resonance imagingMiddle Agedmedicine.diseaseOswestry Disability IndexSurgerymedicine.anatomical_structureSpinal FusionTreatment Outcomefacet fluid signalSurgeryFemaleNeurology (clinical)facet fusionSpondylolisthesisbusiness030217 neurology & neurosurgeryIntervertebral Disc DisplacementJournal of neurological surgery. Part A, Central European neurosurgery
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Spinal anaesthesia in a patient with post-spine surgery dural ectasia.

2013

Dural sac ectasia is a very infrequent anatomical abnormality, usually caused by connective tissue diseases, as Marfan syndrome. Very few cases have been described being a consequence of a previous spine surgical procedure. We describe the case of an elderly patient who should be operated on twice due to sub-occlusive colon disease. Surgery was performed under spinal anaesthesia. A dural sac ectasia was suspected after the first procedure and the abdominal X-ray was reviewed. The characteristics of the anatomical alteration and the course of both anaesthetic procedures were described. X-ray and CT images were provided.

musculoskeletal diseasesMarfan syndromeMalemedicine.medical_specialtymedicine.medical_treatmentDura materMegacolonPeritonitisCritical Care and Intensive Care MedicineAnesthesia SpinalFatal OutcomePostoperative ComplicationsEctasiaColostomySurgical Wound DehiscencemedicinePressureHumansColectomyInjections SpinalColectomyAbdomen AcuteAged 80 and overSigmoid DiseasesMegacolonbusiness.industryDural ectasiaColostomyLaminectomyLaminectomymedicine.diseaseBupivacaineCombined Modality TherapySurgeryAnti-Bacterial AgentsAnesthesiology and Pain Medicinemedicine.anatomical_structureDura MaterbusinessDilatation PathologicIntestinal VolvulusRevista espanola de anestesiologia y reanimacion
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A real life comparison of the effectiveness of adalimumab and golimumab in moderate-to-severe ulcerative colitis, supported by propensity score analy…

2018

Abstract Background Adalimumab and golimumab are effective in the treatment of moderate to severe ulcerative colitis. Aims We reported the comparative effectiveness of adalimumab and golimumab in ulcerative colitis. Methods 118 patients treated with adalimumab and 79 treated with golimumab were included and evaluated at 8 weeks and at the end of follow up. Results Overall clinical benefit was 72.6% at 8 weeks and 58.9% at the end of follow up. Patients with longer disease duration and those treated with adalimumab had a better outcome. Clinical benefit was 78.8% in adalimumab patients and 63.3% in golimumab patients (p = 0.026) after 8 weeks; it was 66.9% in adalimumab patients and 46.8% in…

musculoskeletal diseasesModerate to severeAdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaBiologicDisease durationAdalimumab; Biologics; Golimumab; Ulcerative colitis; Adalimumab; Adult; Antibodies Monoclonal; Colitis Ulcerative; Female; Humans; Italy; Logistic Models; Male; Middle Aged; Propensity Score; Proportional Hazards Models; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alphaUlcerativeBiologicsGolimumabSeverity of Illness IndexTreatment failureAntibodies03 medical and health sciences0302 clinical medicineInternal medicineMonoclonalAdalimumabmedicineHumansskin and connective tissue diseasesAdalimumab; Biologics; Golimumab; Ulcerative colitis; Hepatology; GastroenterologyPropensity ScoreProportional Hazards ModelsHepatologybusiness.industryTumor Necrosis Factor-alphaGastroenterologyAdalimumabAntibodies MonoclonalMiddle Agedmedicine.diseaseColitisUlcerative colitishumanitiesGolimumabLogistic ModelsTreatment OutcomeUlcerative colitisItaly030220 oncology & carcinogenesisPropensity score matching030211 gastroenterology & hepatologyColitis UlcerativeFemalebusinessmedicine.drug
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Successful treatment of primary chronic osteomyelitis in SAPHO syndrome with bisphosphonates.

2008

Summary The treatment of the painful osteomyelitis in patients with SAPHO syndrome (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis) is often a problem. A 53-year-old woman had experienced palmo-plantar pustular skin lesions for four years, and in the past two years complained about progressive breath-and movement-dependent pain of the sternum. On examination she had extensive palmoplantar pustules and a painful swelling in the area of the right sternoclavicular joint. The three-phase bone scintigraphy showed a strong focal enrichment in the right sternoclavicular joint and at the transition from the manubrium to the corpus sterni suggesting active osteo-chondritis. Initially prednisolo…

musculoskeletal diseasesSAPHO syndromemedicine.medical_specialtyHyperostosisDermatologySynovitismedicineHumansAcnemedicine.diagnostic_testBone Density Conservation AgentsDiphosphonatesbusiness.industryOsteomyelitisAcquired Hyperostosis SyndromeOsteomyelitisMiddle Agedmedicine.diseasePustulosisDermatologySurgeryTreatment OutcomeBone scintigraphyChronic DiseaseFemaleOsteitismedicine.symptombusinessJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
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COMPliance and Arthralgia in Clinical Therapy: the COMPACT trial, assessing the incidence of arthralgia, and compliance within the first year of adju…

2014

5 Office-based Professional Association Gynecologic Oncologists e.V. in Germany (BNGO e.V.), Berlin; 6 Background: This prospective study evaluated the relationship between arthralgia and compliance during the first year of adjuvant anastrozole therapy in postmenopausal women with hormone receptor-positive early breast cancer. Patients and methods: COMPliance and Arthralgia in Clinical Therapy (COMPACT) was an open-label, multicenter, noninterventional study conducted in Germany. Patients had started adjuvant anastrozole 3-6 months before the study start. The primary end points were arthralgia, compliance, and the relationship between compliance and arthralgia, assessed at specific time poi…

musculoskeletal diseasesmedicine.medical_specialtyAntineoplastic Agents Hormonalmedicine.medical_treatmentSpecific timeAnastrozoleBreast NeoplasmsAnastrozoleMedication AdherenceBreast cancerInternal medicineNitrilesmedicineHumansProspective Studiesskin and connective tissue diseasesProspective cohort studyAgedbusiness.industryDrug SubstitutionIncidence (epidemiology)IncidenceHematologyMiddle AgedTriazolesmedicine.diseaseArthralgiaSurgeryCompliance (physiology)Clinical therapyTreatment OutcomeOncologyChemotherapy AdjuvantFemalebusinessAdjuvantmedicine.drugAnnals of oncology : official journal of the European Society for Medical Oncology
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The PROMISE study protocol: a multicenter prospective study of process optimization with interdisciplinary and cross-sectoral care for German patient…

2021

Background and purpose — Knee and hip replacement are common and increasing procedures, and an optimized care process that could be implemented in different settings would be useful. The PROMISE trial investigates whether a new care process works equally in different German settings and how the results compare with current non-standardized care. Patients and methods — This multi-center prospective mixed-method study includes 2,000 German patients receiving arthritis-related hip or knee endoprostheses. An interdisciplinary and cross-sectoral care process was developed and implemented in 3 German hospitals with different levels of care, and corresponding rehabilitation centers were included t…

musculoskeletal diseasesmedicine.medical_specialtyCare processArthroplasty Replacement HipMEDLINEHip replacement (animal)German03 medical and health sciencesDisability Evaluation0302 clinical medicineGermanySurveys and QuestionnairesmedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineProspective StudiesProspective cohort studyArthroplasty Replacement KneePain MeasurementProtocol (science)Orthopedic surgeryPatient Care Team030222 orthopedicsbusiness.industryGeneral MedicineProstheses and Implantslanguage.human_languageTreatment OutcomeCross sectorallanguagePhysical therapyQuality of LifeSurgerybusinessRD701-811Research ArticleActa Orthopaedica
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Patient Specific Instrumentation for Total Knee Arthroplasty: a Literature Review

2014

During the past decade, total knee arthroplasty (TKA) has been markedly increased. Recently, patient-specific custom cutting guides have been commercially introduced in order to achieve an accurate component alignment during TKA. In fact, these cutting blocks are specific to a patient’s knee anatomy and should help the surgeons to perform bone cuts, reducing the complexity of conventional alignment and sizing tools. Nevertheless, there are critical arguments against patient-specific cutting guides for routine use, such as poor evidence and higher costs. Additionally, there are still no mild and long-term results available that describe the clinical outcomes following patient-specific instru…

musculoskeletal diseasesmedicine.medical_specialtyKnee JointTotal knee arthroplastytotal knee arthroplasty patient specific instrumentation PSI knee ProsthesisSettore MED/33 - Malattie Apparato LocomotoreMedicineHumansOrthopedics and Sports MedicineComponent alignmentInstrumentation (computer programming)Arthroplasty Replacement KneeEvidence-Based Medicinebusiness.industryMagnetic Resonance ImagingSurgeryTreatment OutcomePatient specific instrumentationSurgery Computer-AssistedOrthopedic surgeryPractice Guidelines as TopicPhysical therapySurgerybusinessKnee ProsthesisTomography X-Ray Computed
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