Search results for "OUTCOME"
showing 10 items of 5148 documents
Can adjunctive corticosteroid therapy improve patient-centered outcomes following third molar surgery? A systematic review
2021
Third molar surgery is frequently associated with postoperative discomfort such as pain, edema and trismus. We aimed to evaluate the current evidence on the efficacy of adjunctive corticosteroid therapy in improving patient-centered outcomes following third molar surgery.This systematic review assessed and searched PubMed, Google scholar, Scopus, web of science, clinicaltrials.gov and Cochrane central for controlled trials, up to May 2021. The primary outcome measures were patient-centered outcomes such as quality of life following the use of adjunctive corticosteroid therapy in third molar removal. Only randomized controlled trials published in English language were included.A total of 355…
Attributions by team members for team outcomes in finnish working life
2010
This study focuses on teamwork in Finnish working life. Through a wide cross-section of teams the study examines the causes to which team members attribute the outcomes of their teams. Qualitative data was collected from 314 respondents. They wrote 616 stories to describe memorable experiences of success and failure in teamwork. The stories revealed 1930 explanations. The findings indicate that both favorable and unfavorable team outcomes are perceived as being caused by the characteristics of team members, relationships between members, team communication, team structure, team goals, team leadership, and external forces. The types represent different attribution levels in the context of or…
Peri-Implant Behavior of Tissue Level Dental Implants with a Convergent Neck
2021
Introduction: The aim of this retrospective study was to analyze the radiographic peri-implant bone loss of bone level implants and tissue level implants with a convergent neck in screw-retained single crowns and in screw-retained fixed partial prostheses, after two years of functional loading. Materials and methods: The sample was divided into two groups according to their type: Group I: supracrestal implants with convergent transmucosal neck
Evaluation of Surgical Outcomes of Abdominal Radical Hysterectomy and Total Laparoscopic Radical Hysterectomy for Cervical Cancer: A Retrospective An…
2022
Although a surgical approach is one of the key treatments for stages IA1-IIA2, results of the Laparoscopic Approach to Cervical Cancer (LACC) published in 2018 radically changed the field, since minimally invasive surgery was associated with a four-fold higher rate of recurrence and a six-fold higher rate of all-cause death compared to an open approach. We aimed to evaluate surgical outcomes of abdominal radical hysterectomy (ARH) and total laparoscopic radical hysterectomy (TLRH) for cervical cancer, including data collected before the LACC trial. In our retrospective analysis, operative time was significantly longer in TLRH compared to ARH (p < 0.0001), although this disadvantage could…
Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial
2022
Background and purpose: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods: This was a phase II, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial. Participants diagnosed with definite, probable or probable laboratory-supported ALS were assigned to receive RNS60 or placebo administered for 24 weeks intravenously (375 ml) once a week and via nebul…
Is personality related to permanent earnings? Evidence using a twin design
2018
Using twin survey combined with register-based panel data on labor market outcomes, the authors examine the association between personality characteristics and long-term earnings among prime working-age individuals. The long-term earnings were measured over the 1990–2008 period. The sample contains 4,642 twin pairs, of which 53% are females. In contrast to previous studies, this paper uses the within-twin dimension of the data to control for shared family background and confounding genetic factors. The results suggest that unobserved genetic differences may introduce omitted variable bias in standard ordinary least square results. After controlling for shared environment and genetic backgro…
Losing a Job and (Dis)incentives to Move
2020
Tässä tutkimuksessa tarkastellaan työpaikan menettämisen ja muiden taloudellisten ja ei-taloudellisten kannustimien vaikutuksia alueelliseen muuttoliikkeeseen. Käytämme yhdistettyä työnantaja-työntekijäaineistoa sekä tietoja alueellisista asuntomarkkinoista. Työpaikan menettäneillä tarkoitamme heitä, jotka menettävät työpaikkansa toimipaikan sulkemisen tai joukkoirtisanomisen takia. Työpaikan menetys lisää henkilön muuttoalttiutta noin 80 prosentilla. Työpaikan menettäneet näyttäisivätkin reagoivan taloudellisiin kannustimiin, sillä alhainen oletettu palkkataso ja korkeat asuntojen hinnat alueella ovat yhteydessä lisääntyneeseen muuttoalttiuteen alueelta, josta henkilö on jäänyt työttömäksi…
Football match attendance in Finland
2022
Football fans prefer to see their favourite team win in close matches. Compared to other forms of entertainment, the outcome of sport game is unknown beforehand. Opera audience knows the plot in advance, but in football the winner is revealed only after 90 minutes. The scientific literature of modern sport economics demand theory implies that successful leagues must be based on relatively even competition. This degree of parity within a league is labelled as competitive balance. Sport leagues usually claim that outcome uncertainty is necessary to maintain interest among fans. In this paper, uncertainty of outcome hypothesis is tested applying football data from the highest tier in Finnish m…
Could PD-1/PDL1 immune checkpoints be linked to HLA signature?
2019
The outstanding clinical expansion of monoclonal antibodies (mAbs) to programmed cell death receptor-1 (PD-1) (nivolumab and pembrolizumab) and PD-1 ligand-1 (PDL-1) (atezolizumab, avelumab and durvalumab) has received an increasing level of interest regarding immunotherapy and multidrug combinations, for the treatment of a number of common human malignancies. Some patients treated with these agents receive remarkable benefits in term of quality of life, progression-free (PFS) and overall survival (OS). However, a significant percentage of these patients experience immune-related adverse events (irAEs), while others present with an ultra-rapid disease progression, defined as hyperprogressio…
Noninvasive neurostimulation methods for migraine therapy: The available evidence.
2016
Background Migraine is one of the most disabling neurological disorders. The current pharmacological armamentarium is not satisfying for a large proportion of patients because the responder rate does not exceed 50% on average and the most effective drugs often induce intolerable side effects. During recent years, noninvasive central and peripheral neuromodulation methods have been explored for migraine treatment. Overview A review of the available evidence suggests that noninvasive neuromodulation techniques could be beneficial for migraine patients. The transcranial stimulation methods allow modulating selectively cortical activity and can thus be curtailed to the patient’s pathophysiologi…