Search results for "OUTCOME"

showing 10 items of 5148 documents

Accuracy of the fetal cerebroplacental ratio for the detection of intrapartum compromise in nonsmall fetuses

2018

Objective: To study the accuracy of the cerebroplacental ratio (CPR) for the detection of intrapartum fetal compromise (IFC) in fetuses growing over the 10th centile.Methods: This was a prospective...

AdultMaleMiddle Cerebral Arterymedicine.medical_specialtyeducationGestational AgeFetal DistressUltrasonography PrenatalUmbilical Arteries03 medical and health sciences0302 clinical medicinePredictive Value of TestsPregnancymedicineFetal growthBirth WeightHumansProspective Studies030212 general & internal medicinereproductive and urinary physiologyFetus030219 obstetrics & reproductive medicineObstetricsbusiness.industryInfant NewbornPregnancy OutcomeReproducibility of ResultsObstetrics and GynecologyFetal dopplerPulsatile Flowembryonic structuresPediatrics Perinatology and Child HealthFemalebusinessThe Journal of Maternal-Fetal & Neonatal Medicine
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Effects of Botulinum Toxin A on Allodynia in Chronic Migraine: An Observational Open-Label Two-Year Study.

2019

<b><i>Background:</i></b> Onabotulinumtoxin A (OBT-A) is a treatment option for chronic migraine (CM), though the possible effect on central sensitization and allodynia is still unknown. <b><i>Aims:</i></b> The present study aimed to evaluate (1) the long-term outcome of allodynia in a group of CM treated with OBT-A (2) if the presence and severity of allodynia could predict the long-term effect of OBT-A (3) if the improvement of allodynia, could contribute to the clinical efficacy of OBT-A. <b><i>Methods:</i></b> This was an observational, open-label, cohort study conducted on 99 CM patients treated for 1 year and 44 p…

AdultMaleMigraine Disorders030204 cardiovascular system & hematologyAllodyniaCohort Studies03 medical and health sciences0302 clinical medicineChronic MigraineBotulinum toxinMedicineHumansBotulinum Toxins Type ADepression (differential diagnoses)Chronic migrainebusiness.industrymusculoskeletal neural and ocular physiologyCentral sensitizationMiddle Agedmedicine.diseaseBotulinum toxinSleep deprivationNociceptionAllodyniaTreatment OutcomeNeurologyMigraineNeuromuscular AgentsHyperalgesiaAnesthesiaAnxietyFemaleNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgerymedicine.drugEuropean neurology
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Web-Based Acceptance and Commitment Therapy for Depressive Symptoms With Minimal Support : A Randomized Controlled Trial

2015

Low-intensity interventions for people suffering from depressive symptoms are highly desirable. The aim of the present study was to investigate the outcomes of a web-based acceptance and commitment therapy (ACT)–based intervention without face-to-face contact for people suffering from depressive symptoms. Participants ( N = 39) with depressive symptoms were randomly assigned to an Internet-delivered acceptance and commitment therapy (iACT) intervention or a waiting list control condition (WLC). Participants were evaluated with standardized self-reporting measures (Beck Depression Inventory [BDI-II], Symptom Checklist–90 [SCL-90], Acceptance and Action Questionnaire [AAQ-2], Five Facet Mind…

AdultMaleMindfulnessmedicine.medical_treatmenteducationPsychological interventionFive Facet Mindfulness QuestionnaireAcceptance and commitment therapylaw.inventionminimal supportdepressive symptomsArts and Humanities (miscellaneous)Randomized controlled triallawSurveys and QuestionnairesDevelopmental and Educational PsychologymedicineHumansta515Psychiatric Status Rating ScalesDepressive DisorderInternetCognitive Behavioral TherapyDepressionBeck Depression InventoryInternet treatmentThought suppressionMiddle Agedremindersacceptance and commitment therapyClinical PsychologyTreatment OutcomeCognitive therapyFemaleSelf ReportPsychologyMindfulnessClinical psychologyBehavior Modification
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Randomized study comparing two tongue base surgeries for moderate to severe obstructive sleep apnea syndrome

2009

To compare the effectiveness and morbidity of the tongue base radiofrequency and tongue base suspension techniques combined with uvulopalatopharyngoplasty for moderate to severe obstructive sleep apnea.Prospective and randomized surgical trial at a university hospital.In total, 57 patients received either tongue base radiofrequency reduction (n = 29) or tongue base suspension (n = 28). Apnea-hypopnea index, lowest oxygen saturation (polysomnography), Epworth score, and side effects were assessed. Success was defined as aor =50 percent reduction and final apneahypopnea index15/h, and an Epworth score11.The success rates of the two procedures were 57.1 percent and 51.7 percent, respectively (…

AdultMaleModerate to severemedicine.medical_specialtyPolysomnographymedicine.medical_treatmentSeverity of Illness IndexTongue Baselaw.inventionTongueRandomized controlled triallawHumansMedicineProspective StudiesAgedSleep Apnea ObstructiveChi-Square Distributionbusiness.industryUvulopalatopharyngoplastyMiddle Agedmedicine.diseaseOtorhinolaryngologic Surgical ProceduresSurgeryObstructive sleep apneaLogistic ModelsTreatment OutcomeOtorhinolaryngologyCatheter AblationFemaleSurgerybusinessOtolaryngology–Head and Neck Surgery
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Retrospective analysis of survival rates and marginal bone loss on short implants in the mandible

2011

Objectives: Short implants have become an interesting alternative to bone augmentation in dental implantology. Design of shorter implants and longer surveillance times are a current research issue. The goal of this study was to show the survival rates of short implants below 9 mm in the partly edentulous mandibular premolar and molar regions with fixed prosthetics. Marginal vertical and 2D bone loss was evaluated additionally. Different implant designs are orientationally evaluated. Material and Methods: A total of 247 dental implants with fixed prosthetics (crowns and bridges) in the premolar and molar region of the mandible were evaluated; 47 implants were 9 mm or shorter. Patient data we…

AdultMaleMolarAdolescentAlveolar Bone LossDentistryStatistics NonparametricRadiography PanoramicRetrospective analysisPremolarHumansMedicineDental Restoration FailureSurvival rateAgedRetrospective StudiesAged 80 and overDental ImplantsOrthodonticsbusiness.industryJaw Edentulous PartiallyDental prosthesisMandibleMiddle AgedSurvival RateShort implantsTreatment Outcomemedicine.anatomical_structureDental Prosthesis DesignFemaleDental Prosthesis Implant-SupportedImplantOral SurgerybusinessClinical Oral Implants Research
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Maintenance of Class III Trifurcated Molars Versus Implant Placement in Regenerated Extraction Sockets: Long-Term Results of 2 Cases

2011

Studies to date have reached differing conclusions regarding the long-term prognosis of teeth with class III furcation involvement. Replacement of such teeth with implants could be an alternative. This report compares the treatment outcomes of 2 cases with similar disease progression: 1 treated by implant therapy and 1 maintained with nonsurgical periodontal treatment. Two patients with advanced chronic periodontitis and class III furcation involvement of all molars were treated. Case 1 received a conservative periodontal and antibiotic treatment, followed by 15 years of maintenance. In case 2, the molars were extracted and replaced with implants, and the implants were observed for 7 years.…

AdultMaleMolarDentistryMandibleClass iiiFurcation InvolvementTooth LossMaxillaHumansMedicineTooth SocketDental ImplantsOrthodonticsSocket preservationbusiness.industryFurcation DefectsDental Implantation EndosseousDental Plaque IndexMandibleAlveolar Ridge AugmentationLong term resultsMolarSurvival AnalysisImplant placementTreatment OutcomeMaxillaChronic PeriodontitisTooth ExtractionGuided Tissue Regeneration PeriodontalDental ScalingFemaleOral SurgerybusinessFollow-Up StudiesJournal of Oral Implantology
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Efficacy of naproxen with or without esomeprazole for pain and inflammation in patients after bilateral third molar extractions: a double blinded cro…

2017

Background Using a double-blinded randomized crossover design, this study aimed to evaluate acute postoperative pain management, swelling and trismus in 46 volunteers undergoing extractions of the two lower third molars, in similar positions, at two different appointments who consumed a tablet of either NE (naproxen 500 mg + esomepraz ole 20 mg) or only naproxen (500 mg) every 12 hours for 4 days. Material and Methods Parameters were analyzed: self-reported pain intensity using a visual analog scale (VAS) pre- and postoperative mouth opening; incidence, type and severity of adverse reactions; total quantity consumed of rescue medication; and pre- and postoperative swelling. Results Female v…

AdultMaleMolarNaproxenmedicine.medical_specialtyAdolescentVisual analogue scaleTrismuslaw.inventionEsomeprazoleYoung Adult03 medical and health sciencesCOMPLICAÇÕES PÓS-OPERATÓRIASNaproxen0302 clinical medicinePharmacotherapyDouble-Blind MethodRandomized controlled triallawHumansPain ManagementMedicineGeneral DentistryInflammationPain PostoperativeCross-Over Studiesbusiness.industryResearchAnti-Inflammatory Agents Non-SteroidalEsomeprazoleProton Pump Inhibitors:CIENCIAS MÉDICAS [UNESCO]Crossover studySurgeryTreatment OutcomeOtorhinolaryngology030220 oncology & carcinogenesisAnesthesiaUNESCO::CIENCIAS MÉDICASTooth ExtractionDrug Therapy CombinationFemaleMolar ThirdSurgeryOral Surgerymedicine.symptombusiness030217 neurology & neurosurgerymedicine.drug
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Efficacy and complications associated with a modified inferior alveolar nerve block technique. A randomized, triple-blind clinical trial

2014

Objectives: To compare the efficacy and complication rates of two different techniques for inferior alveolar nerve blocks (IANB). Study Design: A randomized, triple-blind clinical trial comprising 109 patients who required lower third molar removal was performed. In the control group, all patients received an IANB using the conventional Halsted technique, whereas in the experimental group, a modified technique using a more inferior injection point was performed. Results: A total of 100 patients were randomized. The modified technique group showed a significantly higher onset time in the lower lip and chin area, and was frequently associated to a lingual electric discharge sensation. Three f…

AdultMaleMolarmedicine.medical_specialtyAnestèsia en odontologiaMandibular Nervemedicine.medical_treatmentMandibular nerveBlock (permutation group theory)OdontologíaInferior alveolar nerveFacial nerveInjectionsDouble-Blind MethodmedicineHumansTeeth extractionGeneral DentistryExtracció dentalbusiness.industryNervi facialResearchNerve BlockDent molar:CIENCIAS MÉDICAS [UNESCO]MolarCiencias de la saludChinInjeccionsSurgeryClinical trialTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologyAnesthesiaTooth ExtractionUNESCO::CIENCIAS MÉDICASNerve blockFemaleSurgeryOral SurgeryAnesthesia in dentistryComplicationbusiness
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Mandibular Molar Root Resection Versus Implant Therapy: A Retrospective Nonrandomized Study

2009

AbstractSuccess rates for both periodontal and implant therapy are often dependent on site and tooth type. For periodontally involved mandibular molars, the decision to hemisect or to extract and place an implant is often complicated. The purpose of the present study was to evaluate the outcomes of the aforementioned treatment modalities for mandibular molars in a private practice setting. A retrospective chart review was performed. In one group of patients (n = 32), 56 mandibular first or first and second molars were treated by hemisection (Group H). A second group (n = 28) received 36 implants in the mandible to replace periodontally involved first or first and second molars (Group I). Al…

AdultMaleMolarmedicine.medical_treatmentDentistryMandibleStatistics NonparametricDental Implants Single-ToothPostoperative Complicationsstomatognathic systemPeriodontal Attachment LossHumansMedicineDental Restoration FailureLongitudinal StudiesTooth RootDental Restoration PermanentDental implantAgedRetrospective StudiesTooth NonvitalOrthodonticsbusiness.industryFurcation DefectsDental Implantation EndosseousMandibleFurcation defectRetrospective cohort studyMiddle AgedMolarClinical trialTreatment OutcomeTooth ExtractionFemaleImplantOral SurgerybusinessDental restorationJournal of Oral Implantology
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Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter p…

2010

Adrenocortical carcinoma (ACC) is a rare neoplasm characterized by poor prognosis. First-line systemic treatments in advanced disease include mitotane, either alone or in combination with chemotherapy. Studies evaluating second-line therapy options have obtained disappointing results. This trial assessed the activity and toxicity of gemcitabine plus metronomic fluoropyrimidines in heavily pretreated advanced ACC patients. From 1998 to 2008, 28 patients with advanced ACC progressing after mitotane plus one or two systemic chemotherapy lines were enrolled. They received a combination of i.v. gemcitabine (800 mg/m2, on days 1 and 8, every 21 days) and i.v. 5-fluorouracil protracted infusion (2…

AdultMaleMucositisOncologyAntimetabolites AntineoplasticCancer Researchmedicine.medical_specialtyAdrenocortical carcinomaSettore MED/06 - Oncologia MedicaEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPhases of clinical researchDeoxycytidineGastroenterologyDrug Administration ScheduleCapecitabineEndocrinologyInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineMucositisHumansMitotaneCapecitabineAgedChemotherapybusiness.industryLeukopeniaMiddle Agedmedicine.diseaseThrombocytopeniaGemcitabineAdrenal Cortex NeoplasmsGemcitabineRegimenTreatment OutcomeOncologyFluorouracilDisease ProgressionFemaleFluorouracilbusinessmedicine.drug
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