Search results for "OWL"
showing 10 items of 3255 documents
Helping lecturers address and formulate teaching challenges: an exploratory study
2018
International audience; In this paper we present an exploratory study on the kind of questions or difficulties lecturers point out at the beginning of an educational course – to be addressed in it. These questions happen to be very general and are poorly connected to the knowledge to be taught. We suggest a twofold interpretation of this phenomenon. On the one hand, and in the line of the didactic transposition theory, teachers do not allow themselves to raise questions about the knowledge that is supposed to be their main field of expertise. On the other hand, the prevailing institutional pedagogy does not provide teachers with a fruitful enough conceptual frame to formulate this kind of q…
De la performance musicale dans la Guyane traditionnelle : expression cognitive singulière d?une musique-verbe
2021
Guianese culture and traditional music, here evoked, are various. It is more a transcultural process that, along centuries, gave an original result born in the Americas, in Guiana in this case. It is a form of refoundation, of recreation of cultures and new human beings generally called Creoles. The musical performance, that I study here, is the echo of social and cultural space of this reformulation of thought, life, and conception of the world. It is, as well, a mean of transposition and transformation of the values issued of diverse sources and categories. It is in no way a second-rate cultural practice, as it is the place where were born philosophies and actions for common life as well …
Introduction to the Book and the Comparative Study
2016
Chapter 1 of Re-Becoming Universities contextualizes and describes the contents of the book based on the study: Change in Networks, Higher Education and Knowledge Societies (CINHEKS). The CINHEKS study was a six country international comparative study focused on the way in which contemporary higher education institutions and networked within and between networked knowledge societies. The countries in focus are Finland, Germany, Portugal, The Russian Federation, The United Kingdom and the United States of America.
Creating Individual Journal Rankings Based on a Community Approach
2010
Selecting appropriate publication outlets is crucial to any researcher. Journal rankings can be used to guide the selection, but their usefulness may be limited for particular audiences. In this paper, it is argued that especially young researchers and researchers in interdisciplinary fields can benefit from targeting research efforts to a specific community. This can be facilitated by an individually built journal ranking that exploits a community building perspective and by a more transparent process of use. The approach introduced here is based on an analysis of both traditional journal rankings and behavior of academic communities. As a result, we present a procedure for building and us…
Vertical Integration due to Software Systems' Modularity
2009
In their product portfolio, OSS/BSS software vendors make products pre-integrated with each other as well as with other related OSS/BSS products. Prior to the full-scale development and integration, it is vital for these vendors to assess which products are reasonable to integrate. Such integration of software may be aimed at achieving different goals, such as: Reducing software integration efforts. Software vendors aim at maximizing their profits, whereas their customers (i.e., CSPs) aim at minimizing their costs by avoiding the integration job. As a result, to approach a win–win scenario, vendors provide already integrated products or subsystems (pre-integrated modules). Sharing similar k…
Relapsed and/or Refractory Mantle Cell Lymphoma: What Role for Temsirolimus?
2012
Mantle Cell Lymphoma (MCL) is associated with a dismal prognosis. Recently, along with the improved understanding of the pathophysiology of this disease, new first line regimens have been established and in addition novel treatment options have entered the clinical arena. In consequence, prognosis of the disease has fortunately improved. We here focus on the rationale, current clinical knowledge and future concepts of Temsirolimus, an inhibitor of mTOR, in the treatment of MCL. At this time this drug has been shown to be effective as single agent for relapsed disease and early combination data show promising results. In addition, with a brief outline of other treatment options, we aim to g…
Adequate Urinary Iodine Concentration among Infants in the Inland Area of Norway
2021
Considering the importance of iodine to support optimal growth and neurological development of the brain and central nervous system, this study aimed to assess and evaluate iodine status in Norwegian infants. We collected data on dietary intake of iodine, iodine knowledge in mothers, and assessed iodine concentration in mother’s breast milk and in infant’s urine in a cross-sectional study at two public healthcare clinics in the inland area of Norway. In the 130 mother–infant pairs, the estimated infant 24-h median iodine intake was 50 (IQR 31, 78) µg/day. The median infant urinary iodine concentration (UIC) was 146 (IQR 93, 250) µg/L and within the recommended median defined by the World He…
Exploring the “Cozy Cabal of Academics, Dealers and Collectors” through the Schøyen Collection
2020
In the wake of the trade in ancient materials, several ethical and political issues arise that merit concern: The decimation of the cultural heritage of war-torn countries, proliferation of corruption, ideological connotations of orientalism, financial support of terrorism, and participation in networks involved in money laundering, weapon sales, human trafficking and drugs. Moreover, trafficking and trading also have a harmful effect on the fabric of academia itself. This study uses open sources to track the history of the private Schø
Awareness and understanding of cancer immunotherapy in Europe.
2014
3053 Background: Use of immunotherapies in the treatment of cancer is growing and a range of new immunotherapeutic strategies are being evaluated. It is important that healthcare providers (HCP) understand these treatments and how they compare with and may complement established therapies. As part of the activities of the POINT expert group, we commissioned a survey of current awareness, attitudes and perceptions of cancer immunotherapy in Europe. Methods: From August-September 2011, 426 healthcare professionals (HCPs: oncologists, surgeons and oncology nurses) from France, Germany, Italy, Spain and the UK (~85 respondents/country) completed online interviews. Representatives of patient ad…
Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Frac…
2014
In this paper, we report new protease inhibitory activity of plakortide E towards cathepsins and cathepsin-like parasitic proteases. We further report on its anti-parasitic activity against Trypanosoma brucei with an IC50 value of 5 mu M and without cytotoxic effects against J774.1 macrophages at 100 mu M concentration. Plakortide E was isolated from the sponge Plakortis halichondroides using enzyme assay-guided fractionation and identified by NMR spectroscopy and mass spectrometry. Furthermore, enzyme kinetic studies confirmed plakortide E as a non-competitive, slowly-binding, reversible inhibitor of rhodesain.