Search results for "OXY"

Retracted: Targeting Mitochondria as Therapeutic Strategy for Metabolic Disorders.

2019

Mitochondria are critical regulator of cell metabolism; thus, mitochondrial dysfunction is associated with many metabolic disorders. Defects in oxidative phosphorylation, ROS production, or mtDNA mutations are the main causes of mitochondrial dysfunction in many pathological conditions such as IR/diabetes, metabolic syndrome, cardiovascular diseases, and cancer. Thus, targeting mitochondria has been proposed as therapeutic approach for these conditions, leading to the development of small molecules to be tested in the clinical scenario. Here we discuss therapeutic interventions to treat mitochondrial dysfunction associated with two major metabolic disorders, metabolic syndrome, and cancer. …

Development of Composites with a Self-Healing Function

2015

This research aimed to realize experimentally the facilevascular self-healing system in epoxy glass fibre reinforced composite. Using flexiblepolytetrafluoroethylene tubes as removable preforms, the channels were embeddedinto both neat epoxy resin and unidirectional glass-fibre reinforced epoxy laminate.Room temperature curable epoxy resin with a surfactant and an amine-basedhardener were the components of the binary healing agent. The specimens oftapered double cantilever beam geometry were subjected to Mode I fracture tests.Fracture of specimens released the healing agent from channels and triggeredself-healing process of the crack. Tested neat epoxy resin specimensdemonstrated recovery o…

Augmentation of weld penetration by flux assisted TIG welding and its distinct variants for oxygen free copper

2021

Abstract A comparative study to investigate the influences of single component fluxes on the depth-to-width ratio (DWR) of oxygen free copper was carried out with novel variants of tungsten inert gas (TIG) welding namely Activated TIG (A-TIG), Flux Bounded TIG (FB-TIG) and Flux Zoned TIG (FB-TIG) processes. The experiments to identify the fluxes delivering the higher DWRs in A-TIG welding among thirteen distinct fluxes were followed by the trials with FB-TIG and FZ-TIG employing those identified DWR fluxes. The fluxes which outperformed with all the techniques were MoO3 & MgO. Reversed Marangoni and arc constriction mechanisms were perceived to be opt for such an increase in DWR. Metallurgi…

The use of calcined paper mill sludge as a chemical precipitant in the simultaneous removal of ammonium and phosphate : paper mill waste recycling an…

2020

Currently, recycling and re-use of materials is extremely important due to the diminishing of natural resources. The objective of the European Union’s circular economy strategy is to increase recycling and the use of industrial waste materials and side streams as secondary raw materials. In this study, a chemical precipitation method to simultaneously remove ammonium nitrogen and phosphate from the liquid phase of anaerobic digestate using calcined paper mill sludge was studied. Papermill sludge is a waste material that forms in the paper-making process. In addition, commercial calcium oxide (CaO) was used as a reference precipitant. The suitability of the formed precipitate’s composition f…

Availability of extractives from various Norway spruce (Picea abies) stumps assortments

2022

Stumps and knotwood of Norway spruce (Picea abies) are valuable sources of wood extractives. Although lignans from knotwood have already been utilized in value-added products, the behavior and valorization of stump-derived extractives are less studied. In this study, the composition of lipophilic and hydrophilic extractives, particularly lignans, from various spruce stump samples (stump bottom, stump heart, and crushed stump samples) stored outside were studied. Lipophilic and hydrophilic extracts were separated with an accelerated solvent extraction (ASE) apparatus using n-hexane and hot water, respectively. The detailed extractives content of samples was then determined by gas chromatogra…

Lipase-catalyzed resolution of β-hydroxy selenides

2006

Abstract Eleven β-hydroxy selenides were kinetically resolved using an immobilized lipase (Amano PS-C II) in toluene in the presence of vinyl acetate at 30 °C. This approach provided, in several cases, both enantiomers in high enantiomeric excess. The role of the size of substituents and the behaviour of cyclic β-hydroxy selenides is also discussed. Enantiopure β-hydroxy selenides are useful building blocks. As an application of this chemistry, enantiopure (1 S ,2 R )-indene oxide was obtained in one step from the proper enantiopure β-hydroxy selenide.

Lipoperoxyl radical scavenging activity of the phytochemical betanin and its aglycone in aqueous/lipid membrane system. Kinetics and mechanistic aspe…

2009

Recent changes in chironomid communities and hypolimnetic oxygen conditions relate to organic carbon in subarctic ecotonal lakes

2018

A key question in aquatic elemental cycling is related to the influence of bottom water oxygen conditions in regulating the burial and release of carbon under climate warming. In this study, we used head capsules of Chironomidae larvae to assess community and diversity change between the past (estimated as Pre-Industrial Period) and present and to reconstruct changes in hypolimnetic oxygen conditions from 30 subarctic ecotonal lakes (northeastern Lapland) using the top-bottom paleolimnological approach applying surface sediment (topmost 0-2 cm) and reference (4-5 cm) samples. Subsequently, we tested the findings against dissolved organic carbon (DOC) concentration of the sites. We found tha…

Biogenic Fenton process - A possible mechanism for the mineralization of organic carbon in fresh waters.

2020

To explore the mechanisms that mineralize poorly bioavailable natural organic carbon (OC), we measured the mineralization of OC in two lake waters over long-term experiments (up to 623 days) at different pH and iron (Fe) levels. Both the microbial and photochemical mineralization of OC was higher at pH acidified to 4 than at the ambient pH 5 or an elevated pH 6. During 244 days, microbes mineralized up to 60% of OC in the 10-mu m filtrates of lake water and more than 27% in the 1-mu m filtrates indicating that large-sized microbes/grazers enhance the mineralization of OC. A reactivity continuum model indicated that the acidification stimulated the microbial mineralization of OC especially i…

Locked-in Syndrome and 18F-fluorodeoxyglucose-positron Emission Tomography/Computed Tomography: Observations from a Case of Basilar Artery Thrombosis

2018

We report the case of a 59-year-old male patient suffering from locked-in syndrome (LIS) following basilar artery thrombosis despite an attempt of thrombolysis. Neurological examination showed quadriplegia and aphonia and a state of coma requiring mechanical ventilation was diagnosed. The use of 18F-fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET) allowed to detect a normal 18F-FDG uptake in the main cerebral cortical areas and a significant reduction of 18F-FDG uptake in both cerebellar hemispheres, compatible with a functional deafferentation, helping confirming the clinical suspicion of LIS. The diagnosis of LIS, according to literature, is based on the clinical assessment…