Search results for "Obligate"

showing 10 items of 80 documents

Snapshots of a shrinking partner: Genome reduction inSerratia symbiotica

2016

AbstractGenome reduction is pervasive among maternally-inherited endosymbiotic organisms, from bacteriocyte- to gut-associated ones. This genome erosion is a step-wise process in which once free-living organisms evolve to become obligate associates, thereby losing non-essential or redundant genes/functions. Serratia symbiotica (Gammaproteobacteria), a secondary endosymbiont present in many aphids (Hemiptera: Aphididae), displays various characteristics that make it a good model organism for studying genome reduction. While some strains are of facultative nature, others have established co-obligate associations with their respective aphid host and its primary endosymbiont (Buchnera). Further…

0301 basic medicineSerratiaRNA Stability030106 microbiologyved/biology.organism_classification_rank.speciesGenomicsGenomeArticle03 medical and health sciencesRNA TransferGammaproteobacteriaCluster AnalysisAmino AcidsModel organismGene030304 developmental biologyGene RearrangementGenetics0303 health sciencesMultidisciplinarybiologyObligate030306 microbiologyved/biologyBacteriocyteGene rearrangementGene Expression Regulation Bacterialbiochemical phenomena metabolism and nutritionbiology.organism_classificationBiosynthetic PathwaysRNA Bacterial030104 developmental biologyEvolutionary biologyGenes BacterialBuchneraGenome Bacterial
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Nature lessons: the whitefly bacterial endosymbiont is a minimal amino acid factory with unusual energetics

2016

Reductive genome evolution is a universal phenomenon observed in endosymbiotic bacteria in insects. As the genome reduces its size and irreversibly losses coding genes, the functionalities of the cell system, including the energetics processes, are more restricted. Several energetic pathways can also be lost. How do these reduced metabolic networks sustain the energy needs of the system? Among the bacteria with reduced genomes Candidatus Portiera aleyrodidarum, obligate endosymbiont of whiteflies, represents an extreme case since lacks several key mechanisms for ATP generation. Thus, to analyze the cell energetics in this system, a genome-scale metabolic model of this endosymbiont was const…

0301 basic medicineStatistics and ProbabilityGenome evolutionAnabolismSystems biology030106 microbiologyCell EnergeticsBiologyModels BiologicalGenomeGeneral Biochemistry Genetics and Molecular BiologyHemiptera03 medical and health sciencesMetabolic flux analysisAnimalsAmino AcidsSymbiosisGeneGenome sizeCarotenoidchemistry.chemical_classificationGeneral Immunology and MicrobiologyObligateApplied MathematicsEnergeticsGeneral MedicineMetabolismbeta Carotenebiology.organism_classificationMetabolic Flux AnalysisAmino acidHalomonadaceae030104 developmental biologychemistryBiochemistryModeling and SimulationEnergy MetabolismGeneral Agricultural and Biological SciencesGenome BacterialMetabolic Networks and PathwaysBacteria
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Seasonal Changes in the Endosymbiotic Consortia of Aphids from the Genus <i>Cinara</i>

2016

Buchnera aphidicola is the primary endosymbiont of aphids with which it maintains an obligate mutualistic symbiotic relationship. Insects also maintain facultative symbiotic relationships with secondary symbionts, and Serratia symbiotica is the most common in aphids. The presence of both symbionts in aphids of the subfamily Lachninae has been widely studied by our group. We examined two closely related aphids, Cinara tujafilina and C. cedri in the present study. Even though both B. aphidicola strains have similar genome sizes and gene contents, the genomes of the two S. symbiotica strains were markedly different. The SCc strain has the smallest genome known for this species, while SCt posse…

0301 basic medicineeducation.field_of_studyFacultativebiologyObligatePopulationfood and beveragesSoil ScienceZoologyPlant ScienceGeneral Medicinebiochemical phenomena metabolism and nutritionbiology.organism_classificationSerratiaAcyrthosiphon pisum03 medical and health sciences030104 developmental biologySymbiosisBotanyCinaraeducationBuchneraEcology Evolution Behavior and SystematicsMicrobes and Environments
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Electrophysiological findings of neuronal ceroid lipofuscinosis in heterozygotes.

1988

Nineteen obligate heterozygotes, 8 individuals at risk of being heterozygote, and 10 patients afflicted with four different forms of neuronal ceroid lipofuscinosis were examined electrophysiologically. The group of obligate heterozygotes was compared to age-matched control groups. Statistically significant differences were found between scotopic b-wave amplitudes, P-ERG amplitudes, and EOG light peaks of the obligate carriers of the juvenile type and the control subjects. The photopic L-ERGs and the latencies of the VEPs were mostly within the normal range. The findings represent the first evidence of functional ophthalmological changes in obligate carriers of neuronal ceroid lipofuscinosis…

AdultPathologymedicine.medical_specialtyHeterozygotegenetic structuresAdolescentPhysiologyBiologyCellular and Molecular NeuroscienceNeuronal Ceroid-LipofuscinosesRisk FactorsmedicineElectroretinographyHumansScotopic visionChildmedicine.diagnostic_testObligateHeterozygote advantageElectrooculographymedicine.diseaseSensory SystemsOphthalmologyElectrophysiologyElectrooculographyChild PreschoolEvoked Potentials VisualNeuronal ceroid lipofuscinosissense organsElectroretinographyPhotopic visionGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
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Behavioural adaptations of argulid parasites (Crustacea: Branchiura) to major challenges in their life cycle.

2015

Fish lice (Argulus spp.) are obligate ectoparasites, which contrary to most aquatic parasites, retain the ability to swim freely throughout the whole of their life. In fish farms, they can quickly increase in numbers and without effective control cause argulosis, which results in the reduced growth and survival of their fish hosts. The morphology of Argulus spp, including their sensory organs, is suitable for both parasitism and free-swimming. By spending a considerable amount of time away from their host, these parasites risk being excessively dispersed, which could endanger mating success. Here we present a review of recent studies on the behaviour of Argulus spp, especially the aggregati…

Aggregative behaviourFish farmingPopulationArgulus coregoniZoologyParasitismReviewHost SpecificityHost-Parasite InteractionsFish DiseasesBehavioural tacticsAnimalsMatingeducationSwimmingeducation.field_of_studyLife Cycle StagesbiologyObligateBehavior AnimalBranchiuraEcologyHost (biology)ReproductionFishesLice InfestationsVectorsbiology.organism_classificationArgulus foliaceusInfectious DiseasesArguloidaFish ectoparasitesHost searchingParasitologyArgulus foliaceusParasitesvectors
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Incipient genome erosion and metabolic streamlining for antibiotic production in a defensive symbiont

2021

Significance Genome reduction is commonly observed in bacteria of several phyla engaging in obligate nutritional symbioses with insects. In Actinobacteria, however, little is known about the process of genome evolution, despite their importance as prolific producers of antibiotics and their increasingly recognized role as defensive partners of insects and other organisms. Here, we show that “Streptomyces philanthi,” a defensive symbiont of digger wasps, has a G+C-enriched genome in the early stages of erosion, with inactivating mutations in a large proportion of genes, causing dependency on its hosts for certain nutrients, which was validated in axenic symbiont cultures. Additionally, overe…

Arthropod Antennaeprotective mutualismEvolutionWaspsBeewolfGenomicsProteomicsGenomeStreptomyces03 medical and health sciencesdefensive symbiosis418AnimalsSymbiosisGene030304 developmental biologyGenetics0303 health sciencesMultidisciplinarybiologyObligate030306 microbiologyHost (biology)fungiBiological Sciencesbiology.organism_classificationStreptomycesAnti-Bacterial Agentsgenome erosionAphidsCommentarybacteriaFemalepseudogenizationGenome BacterialPseudogenesMolecular Chaperones
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Sex in an uncertain world: environmental stochasticity helps restore competitive balance between sexually and asexually reproducing populations

2014

Like many organisms, individuals of the freshwater ostracod species Eucypris virens exhibit either obligate sexual or asexual reproductive modes. Both types of individual routinely co-occur, including in the same temporary freshwater pond (their natural habitat in which they undergo seasonal diapause). Given the well-known two-fold cost of sex, this begs the question of how sexually reproducing individuals are able to coexist with their asexual counterparts in spite of such overwhelming costs. Environmental stochasticity in the form of 'false dawn' inundations (where the first hydration is ephemeral and causes loss of early hatching individuals) may provide an advantage to the sexual subpop…

Balance (metaphysics)Stochastic ProcessesObligateEcologyClimatePopulation DynamicsParthenogenesisEnvironmentBiologyDiapauseModels BiologicalSpecies SpecificityHabitatSpainCrustaceaReproduction AsexualSpiteAnimalsPopulation growthSexMatrix projectionEcology Evolution Behavior and SystematicsJournal of Evolutionary Biology
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Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont.

2011

The genome sequencing of Buchnera aphidicola BCc from the aphid Cinara cedri, which is the smallest known Buchnera genome, revealed that this bacterium had lost its symbiotic role, as it was not able to synthesize tryptophan and riboflavin. Moreover, the biosynthesis of tryptophan is shared with the endosymbiont Serratia symbiotica SCc, which coexists with B. aphidicola in this aphid. The whole-genome sequencing of S. symbiotica SCc reveals an endosymbiont in a stage of genome reduction that is closer to an obligate endosymbiont, such as B. aphidicola from Acyrthosiphon pisum, than to another S. symbiotica, which is a facultative endosymbiont in this aphid, and presents much less gene decay…

Cancer ResearchSerratialcsh:QH426-470RiboflavinPseudogeneGenomeDNA sequencingBacterial ProteinsBuchneraEnterobacteriaceaePhylogeneticsBotanyGeneticsAnimalsAmino AcidsSymbiosisMolecular BiologyPhylogenyGenetics (clinical)Ecology Evolution Behavior and SystematicsGeneticsComparative genomicsObligatebiologyTryptophanbiology.organism_classificationBiological EvolutionAcyrthosiphon pisumlcsh:GeneticsAphidsBuchneraGenome BacterialMetabolic Networks and PathwaysPseudogenesPLoS Genetics
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Specialization and interaction strength in a tropical plant–frugivore network differ among forest strata

2011

The degree of interdependence and potential for shared coevolutionary history of frugivorous animals and fleshy-fruited plants are contentious topics. Recently, network analyses revealed that mutualistic relationships between fleshy-fruited plants and frugivores are mostly built upon generalized associations. However, little is known about the determinants of network structure, especially from tropical forests where plants' dependence on animal seed dispersal is particularly high. Here, we present an in-depth analysis of specialization and interaction strength in a plant-frugivore network from a Kenyan rain forest. We recorded fruit removal from 33 plant species in different forest strata (…

CanopyTropical ClimateObligateEcologySeed dispersalFeeding BehaviorHaplorhiniRainforestStratification (vegetation)UnderstoryBiologyTreesFrugivoreAnimalsSecondary forestEcosystemEcology Evolution Behavior and SystematicsEcology
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Transcriptional regulation and energetics of alternative respiratory pathways in facultatively anaerobic bacteria

1998

Abstract The facultatively anaerobic Escherichia coli is able to grow by aerobic and by anaerobic respiration. Despite the large difference in the amount of free energy that could maximally be conserved from aerobic versus anaerobic respiration, the proton potential and Δg ′ Phos are similar under both conditions. O 2 represses anaerobic respiration, and nitrate represses fumarate respiration. By this the terminal reductases of aerobic and anaerobic respiration are expressed in a way to obtain maximal H + e − ratios and ATP yields. The respiratory dehydrogenases, on the other hand, are not synthesized in a way to achieve maximal H + e − ratios. Most of the dehydrogenases of aerobic respirat…

Cellular waste productAnaerobic respirationFumarate nitrate reductase regulatorCellular respirationAerobic and anaerobic respirationBiophysicsO2-sensingRegulation of energeticsProton potentialCell BiologyBiologyFumarate reductasemedicine.disease_causeObligate aerobeBiochemistryTranscriptional regulationBiochemistrymedicineAnaerobic bacteriaAnaerobic exerciseEscherichia coliBiochimica et Biophysica Acta (BBA) - Bioenergetics
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