Search results for "Observational study"

showing 10 items of 776 documents

Psychometric properties of the updated EORTC module for assessing quality of life in patients with lung cancer (QLQ-LC29): an international, observat…

2020

Abstract: Background The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13) assesses quality of life (QOL) in patients with lung cancer and was the first EORTC module developed for use in international clinical trials. Since its publication in 1994, major treatment advances with possible effects on QOL have occurred. These changes called for an update of the module and its international psychometric validation. We aimed to investigate the scale structure and psychometric properties of the updated lung cancer module, QLQ-LC29, in patients with lung cancer. Methods This international, observational field study was done in…

Malemedicine.medical_specialtyPsychometricsPsychometrics10255 Clinic for Thoracic SurgeryQUESTIONNAIRE610 Medicine & health03 medical and health sciences0302 clinical medicineCronbach's alphaQuality of lifeCarcinoma Non-Small-Cell LungSurveys and QuestionnairesMedicine and Health SciencesmedicineHumans030212 general & internal medicineVALIDITYLung cancerAgedLanguagebusiness.industryQLQ-C30CancerMiddle Agedmedicine.diseaseSmall Cell Lung CarcinomaTRENDShumanitiesConfirmatory factor analysisClinical trialOncology030220 oncology & carcinogenesisQuality of LifePhysical therapyFemaleObservational study2730 OncologyHuman medicinebusinessCLINICAL-TRIALS
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Improvement of motor performance by observational training in elderly people.

2010

Action observation influences action execution; this strong coupling is underlined by an overlap of cortical areas activated during observation and execution of action, and is dependent of specific motor experience. The goal of the present study was to verify if action observation can be used for rehabilitation of elderly people. We tested this question with a protocol of observational practice of 2 frequently used movements: walking and sit-to-stand/back-to-sit. Both tasks were performed at normal and maximal speed before and after training, by 8 elderly subjects. Observational practice led to an increase in walking velocity via an increase in step frequency, but without modification of st…

Malemedicine.medical_specialtyRehabilitationGeneral Neurosciencemedicine.medical_treatmentMovementMotion PerceptionHuman factors and ergonomicsPoison controlWalkingAction (philosophy)Feedback SensoryPractice PsychologicalInjury preventionTask Performance and AnalysismedicineMental representationPhysical therapyImaginationHumansObservational studyFemaleDuration (project management)PsychologyAgedNeuroscience letters
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Robotic assisted prostatic surgery in the Trendelenburg position does not impair cerebral oxygenation measured using two different monitors: A clinic…

2014

Robotic assisted prostatic surgery is frequently used because of its reduced side-effects compared with conventional surgery. During surgery, an extreme Trendelenburg position and CO2 pneumoperitoneum are necessary, which may lead to cerebral oedema, can potentially reduce brain perfusion and therefore could impair cerebral oxygenation. Cerebral oxygen saturation can be measured non-invasively using near-infrared spectroscopy (NIRS).The hypothesis of the present study was that steep Trendelenburg positioning during robotic assisted prostatic surgery impairs cerebral oxygen saturation measured using two different NIRS monitors.Clinical observational study.Primary care university hospital, st…

Malemedicine.medical_specialtyRobotic assistedmedicine.medical_treatmentTrendelenburg positionPerfusion scanningPatient PositioningHead-Down TiltPneumoperitoneummedicineHumansAnesthesiaAgedMonitoring PhysiologicProstatectomySpectroscopy Near-Infraredbusiness.industryProstateBrainRoboticsCarbon DioxideMiddle Agedmedicine.diseaseSurgeryFrontal LobeOxygenPerfusionAnesthesiology and Pain MedicineAnesthesiaCerebrovascular CirculationProstatic surgeryProstate surgeryObservational studybusinessPerfusionPneumoperitoneum ArtificialEuropean journal of anaesthesiology
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Prevalence of Sarcopenia in Community-Dwelling Older Adults in Valencia, Spain.

2020

This study is an observational and cross-sectional study on the prevalence of sarcopenic disease in 202 autonomous older adults

Malemedicine.medical_specialtySarcopeniaHealth Toxicology and MutagenesisprevalenceShort Physical Performance Batterylcsh:MedicineDiseaseMuscle massArticlesarcopeniaolder people03 medical and health sciencesGrip strength0302 clinical medicinemedicineHumans030212 general & internal medicineGeriatric Assessmentolder adultsAgedEuropean Working Group on Sarcopenia in Older People 2 (EWGSOP2)Aged 80 and overHand Strengthbusiness.industrylcsh:RPublic Health Environmental and Occupational Healthmedicine.diseasemusculoskeletal systemGait speedbody regionsCross-Sectional StudiesSpainSarcopeniaPhysical therapymuscle strengthObservational studyFemaleIndependent LivingOlder peoplebusinesshuman activities030217 neurology & neurosurgeryInternational journal of environmental research and public health
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Quality of partnership in patients with erectile dysfunction after sildenafil treatment.

2001

OBJECTIVE A comprehensive investigation on the quality of partnership of male patients with erectile dysfunction (ED) after treatment with sildenafil vs. untreated patients, as perceived by both the patients and their female partners. METHODS This report describes an observational, cross-sectional exploratory study comparing ED patients responsive to sildenafil with ED patients prior to therapy. Assessments included the 'International Index of Erectile Function' (IIEF) and the 'Partnerschaftsfragebogen' (PFB), a partnership questionnaire used in German-speaking countries. The comparability of the two study groups was examined using a stepwise logit model. Significant intergroup differences …

Malemedicine.medical_specialtySildenafilPhosphodiesterase InhibitorsLogistic regressionPiperazinesSildenafil Citratechemistry.chemical_compoundQuality of lifeErectile DysfunctionInternal medicineSurveys and QuestionnairesmedicineHumansPharmacology (medical)SulfonesMarriageGynecologybusiness.industryConfoundingGeneral MedicineMiddle Agedmedicine.diseaseTendernessPsychiatry and Mental healthSexual intercourseErectile dysfunctionCross-Sectional StudieschemistryPurinesObservational studyFemalemedicine.symptombusinessPharmacopsychiatry
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Real-world use of ticagrelor and prasugrel in patients with NSTEMI undergoing percutaneous coronary intervention.

2017

Malemedicine.medical_specialtyTicagrelorPrasugrelAdenosinemedicine.medical_treatmentTreatment outcomeMEDLINE030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicinePercutaneous Coronary InterventionInternal medicinemedicineHumansIn patient030212 general & internal medicineNon-ST Elevated Myocardial InfarctionAgedRetrospective Studiesbusiness.industryPercutaneous coronary interventionRetrospective cohort studyGeneral MedicineMiddle AgedNSTEMITreatment OutcomeEmergency medicineCardiologyPurinergic P2Y Receptor AntagonistsObservational studyFemalebusinessCardiology and Cardiovascular MedicineTicagrelorPrasugrelPrasugrel Hydrochloridemedicine.drugJournal of cardiovascular medicine (Hagerstown, Md.)
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Popliteal Artery Aneurysm Repair in the Endovascular Era: Fourteen-Years Single Center Experience

2015

Abstract To compare outcomes of popliteal artery aneurysm (PAA) repair by endovascular treatment, great saphenous vein (GSV) bypass, and prosthetic bypass. Single center retrospective analysis of patients presenting PAA from 2000 to 2013. Patients were divided into endovascular treatment (group A); GSV bypass (group B); and prosthetic graft bypass (group C). Outcomes were technical success, perioperative mortality, and morbidity. Survival, primary and secondary patency, and freedom from reintervention rate were estimated. Differences in ankle-brachial index (ABI), in-hospital length of stay (InH-Los), red blood cell (RBC) transfusion, and limb loss were reported. Mean follow-up was 49 (medi…

Malemedicine.medical_specialtyTime Factors7100Observational Study610 Medicine & health2700 General MedicineSingle CenterSettore MED/22 - Chirurgia VascolareGroup Blaw.inventionBlood Vessel Prosthesis ImplantationAneurysmRandomized controlled triallawmedicine.arteryPopliteal Artery AneurysmmedicineHumansPopliteal ArteryAgedRetrospective Studiesbusiness.industryGreat saphenous veinEndovascular ProceduresAngiographyRetrospective cohort studyGeneral MedicinePerioperativeMiddle Agedmedicine.diseaseAneurysmPopliteal artery10020 Clinic for Cardiac SurgerySurgeryTreatment OutcomeSurgery Computer-AssistedAnesthesiaFluoroscopyFemaleStentsbusinessFollow-Up StudiesForecastingResearch Article
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Observational multicentric trial performed with doxazosin: evaluation of sexual effects on patients with diagnosed benign prostatic hyperplasia.

2002

<i>Introduction:</i> The aim of our study is to verify the effects of doxazosin on sexual function in patients with benign prostatic hyperplasia (BPH). <i>Materials and Methods:</i> We enrolled 102 patients with BPH, selected by nine Italian Urology Departments. Patients were evaluated with the International Prostatic Symptom Score (I-PSS) and divided into two groups: those with intact sexual activity and those with erectile dysfunction. According to the International Index of Erectile Function (IIEF), the second cohort was divided into three subgroups on the basis of the degree of erectile dysfunction degree (severe, moderate or mild). All patients underwent 3 month…

Malemedicine.medical_specialtyTime FactorsAdenomaUrologyUrologyProstatic Hyperplasiaurologic and male genital diseasesProstatemedicineDoxazosinHumansAdrenergic alpha-AntagonistsGynecologyurogenital systembusiness.industryPenile ErectionDoxazosinHyperplasiamedicine.diseasemedicine.anatomical_structureErectile dysfunctionCase-Control StudiesObservational studySexual functionbusinessmedicine.drugCohort studyFollow-Up Studies
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Low Systolic Blood Pressure and Mortality in Elderly Patients After Acute Myocardial Infarction

2020

Background Optimal blood pressure in elderly patients after acute myocardial infarction is still a matter of debate. In a prospective observational study, we aimed to identify optimal systolic blood pressure during the 48 first hours after admission for acute myocardial infarction and its prognostic value for cardiovascular mortality. Methods and Results From the Observatoire des Infarctus de Côte d'Or survey, all consecutive patients aged >75 years admitted for an acute myocardial infarction in a coronary care unit from 2012 to 2015 and discharged alive were included (n=814). Exclusion criteria were in‐hospital death, cardiogenic shock, and end‐stage renal disease. Average systolic blo…

Malemedicine.medical_specialtyTime FactorsEpidemiologyMyocardial Infarctionacute myocardial infarction030204 cardiovascular system & hematologyelderly patientsRisk Assessment03 medical and health sciencesPatient Admission0302 clinical medicinecardiovascular mortalityInternal medicinemedicineCoronary Heart DiseaseHumansProspective Studies030212 general & internal medicineMyocardial infarctionNon-ST Elevated Myocardial InfarctionOriginal ResearchAgedCardiovascular mortalityAged 80 and overbusiness.industryAge Factorsblood pressurePrognosismedicine.diseaseBlood pressureHeart Disease Risk FactorsCardiologyST Elevation Myocardial InfarctionFemaleObservational studyCardiology and Cardiovascular MedicinebusinessJournal of the American Heart Association
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Weekday and weekend sedentary time and physical activity in differentially active children

2015

To investigate whether weekday-weekend differences in sedentary time and specific intensities of physical activity exist among children categorised by physical activity levels.Cross-sectional observational study.Seven-day accelerometer data were obtained from 810 English children (n=420 girls) aged 10-11 years. Daily average minday(-1) spent in moderate to vigorous physical activity were calculated for each child. Sex-specific moderate to vigorous physical activity quartile cut-off values categorised boys and girls separately into four graded groups representing the least (Q1) through to the most active (Q4) children. Sex- and activity quartile-specific multilevel linear regression analyses…

Malemedicine.medical_specialtyTime FactorsPhysical ExertioneducationPhysical activityPhysical Therapy Sports Therapy and RehabilitationMotor ActivitySex FactorsAccelerometryHumansMedicineOrthopedics and Sports MedicineAccelerometer dataMotor activityChildSedentary timebusiness.industryMultilevel modelCross-Sectional StudiesQuartilePhysical therapyFemaleObservational studySedentary BehaviorbusinessJournal of Science and Medicine in Sport
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