Search results for "Oct"

Acetylated nucleosome assembly on telomeric DNAs

2003

Abstract The role of histone N-terminal domains on the thermodynamic stability of nucleosomes assembled on several different telomeric DNAs as well as on ‘average’ sequence DNA and on strong nucleosome positioning sequences, has been studied by competitive reconstitution. We find that histone tails hyperacetylation favors nucleosome formation, in a similar extent for all the examined sequences. On the contrary, removal of histone terminal domains by selective trypsinization causes a decrease of nucleosome stability which is smaller for telomeres compared to the other sequences examined, suggesting that telomeric sequences have only minor interactions with histone tails. Micrococcal nuclease…

El RDL 6/2019 para la garantía de la igualdad de trato y de oportunidades entre mujeres y hombres en el empleo y la ocupación: Dios y el diablo en la…

2019

 Resumen. El artículo es un comentario crítico del contenido y alcance del recientemente aprobado RDL 6/2019 para la garantía de la igualdad de trato y de oportunidades entre mu­jeres y hombres en el empleo y la ocupación. La valoración positiva que, en general, la norma merece, se basa simplemente en su mera aprobación, que refuerza la idea de que la cuestión de la igualdad efectiva entre hombres y mujeres en el trabajo requiere medidas específicas. Sin embargo, el análisis detallado de los preceptos del RDL 6/2019 que se realiza en el trabajo conduce a la autora a la conclusión de que la mayoría de sus contenidos son insuficientes y que queda pendiente una reforma global y efectivamente t…

Phenology of Migratory Bat Activity Across the Baltic Sea and the South-Eastern North Sea

2014

We compiled the available information on the occurrence and timing of migratory bat activity across the Baltic Sea and south-eastern North Sea coasts and islands, based on ultrasonic monitoring projects at 19 localities in 2007–2009. The data refer to three species; Nathusius' pipistrelle Pipistrellus nathusii, soprano pipistrelle P. pygmaeus and common noctule Nyctalus noctula. Pipistrellus nathusii occurred at all sites (north to 61°N in Finland), while the other species were scarcer, particularly at the northernmost sites. The status of the recorded individuals is unknown. However, the activity most likely was of migrating individuals or individuals on migration stopover, because very fe…

La valutazione retinica mediante Tomografia a Coerenza Ottica (OCT) nel diabete mellito tipo 1.

2008

Tiesību piemērošanas problemātika sauszemes transportlīdzekļu īpašnieku civiltiesiskās atbildības obligātās apdrošināšanas likumā

2016

Pētāmā darba mērķis ir izpētīt un analizēt Sauszemes transportlīdzekļu īpašnieku civiltiesiskās atbildības obligātās apdrošināšanas likuma piemērošanas problemātiku un rast risinājumu pareizai tiesību normu piemērošanai un tulkošanai izmantojot tiesību normu interpretācijas metodes. Darbā ir apkopota pētāmā likumā lietotās terminoloģijas problemātika un sniegti autores ieteikumi tās uzlabošanai. Aplūkoti ar šo likumu nenoregulētie problēmjautājumi un risinātu šo problēmjautājumu faktiskā atbilstība un piederību civiltiesiskās atbildības obligātās apdrošināšanas nozarei. Visbeidzot analizēti Latvijas Republikas tiesas spriedumi un tajos ietvertās atziņas attiecībā uz Sauszemes transportlīdze…

Synthesis, characterization, and in vitro antimicrobial activity of organotin(IV) complexes with triazolo-pyrimidine ligands containing exocyclic oxy…

2005

Abstract Tri-organotin(IV) complexes of the triazolo-pyrimidine derivatives 4,5-dihydro-5-oxo-[1,2,4]triazolo-[1,5 a ]pyrimidine (5HtpO), 4,7-dihydro-5-methyl-7-oxo-[1,2,4]triazolo-[1,5 a ]pyrimidine (HmtpO), and 4,5,6,7-tetrahydro-5,7-dioxo-[1,2,4]triazolo-[1,5 a ]pyrimidine (H 2 tpO 2 ), and the diorganotin derivative n -Bu 2 Sn(tpO 2 ), were synthesized and characterized by means of infrared and 119 Sn Mossbauer spectroscopy. In all the complexes obtained the triazolopyrimidines act as multidentate ligands producing polymeric structures. A trigonal bipyramidal arrangement of the ligands around the tin atom is proposed for triorganotin(IV) derivatives, with organic groups on the equatoria…

Structural investigations on diorgano- and triorganotin(IV) derivatives of [meso-tetra(4-sulfonatophenyl)porphine]metal chlorides.

2006

Abstract Several new complexes of organotin(IV) moieties with MCln[meso-tetra(4-sulfonatophenyl)porphine], (R2Sn)2MCln[meso-tetra(4-sulfonatophenyl)-porphinate]s and (R3Sn)4MCln [meso-tetra(4-sulfonatophenyl)porphinate]s, [M = Fe(III), Mn(III): n = 1, R = Me, n-Bu; Ph; M = Sn(IV): n = 2, R = Me, n-Bu] have been synthesized and their solid state configuration investigated by infrared (IR) and Mossbauer spectroscopy, and by 1H and 13C NMR in D2O. The electron density on the metal ion coordinated inside the porphyrin ring is not influenced by the organotin(IV) moieties bonded to the oxygen atoms of the side chain sulfonatophenyl groups, as it has been inferred on the basis of Mossbauer spectro…

Solemne acte d'obertura del curs acadèmic 2004/2005 i lliurament de Premis Extraordinaris de doctorat

2004

Solemne acte d'obertura del curs acadèmic 2004-2005. La lliçó magistral va ser del Dr. Manuel García Ferrando, catedràtic de Sociologia.

Gatekeeper of pluripotency: A common Oct4 transcriptional network operates in mouse eggs and embryonic stem cells

2011

Abstract Background Oct4 is a key factor of an expanded transcriptional network (Oct4-TN) that governs pluripotency and self-renewal in embryonic stem cells (ESCs) and in the inner cell mass from which ESCs are derived. A pending question is whether the establishment of the Oct4-TN initiates during oogenesis or after fertilisation. To this regard, recent evidence has shown that Oct4 controls a poorly known Oct4-TN central to the acquisition of the mouse egg developmental competence. The aim of this study was to investigate the identity and extension of this maternal Oct4-TN, as much as whether its presence is circumscribed to the egg or maintained beyond fertilisation. Results By comparing …

Hydrophobicity of ionisable compounds studied by countercurrent chromatography

2011

Countercurrent chromatography (CCC) is a liquid chromatography technique in which the stationary phase is also a liquid. The main chemical process involved in solute separation is partitioning between the two immiscible liquid phases: the mobile phase and the support-free liquid stationary phase. The octanol-water partition coefficients (P(o/w)) is the accepted parameter measuring the hydrophobicity of molecules. It is considered to estimate active principle partitioning over a biomembrane. It was related to the substance biological activity. CCC is able to work with an octanol stationary phase and an aqueous mobile phase. In this configuration, CCC is a useful and easy alternative to measu…