Search results for "Oct"
showing 10 items of 3052 documents
Bromodomain factor 1 (Bdf1) protein interacts with histones
2001
AbstractUsing a yeast two-hybrid assay we detected an interaction between the N-terminal region of histone H4 (amino acids 1–59) and a fragment of the bromodomain factor 1 protein (Bdf1p) (amino acids 304–571) that includes one of the two bromodomains of this protein. No interaction was observed using fragments of histone H4 sequence smaller than the first 59 amino acids. Recombinant Bdf1p (rBdf1p) demonstrates binding affinity for histones H4 and H3 but not H2A and H2B in vitro. Moreover, rBdf1p is able to bind histones H3 and H4 having different degrees of acetylation. Finally, we have not detected histone acetyltransferase activity associated with Bdf1p.
Unveiling novel interactions of histone chaperone Asf1 linked to TREX-2 factors Sus1 and Thp1
2014
13 páginas, 7 figuras, 2 yablas
Hif1 Is a Component of Yeast Histone Acetyltransferase B, a Complex Mainly Localized in the Nucleus
2004
Hat1 is the catalytic subunit of the only type B histone acetyltransferase known (HAT-B). The enzyme specifically acetylates lysine 12, and to a lesser extent lysine 5, of free, non-chromatin-bound histone H4. The complex is usually isolated with cytosolic fractions and is thought to be involved in chromatin assembly. The Saccharomyces cerevisiae HAT-B complex also contains Hat2, a protein stimulating Hat1 catalytic activity. We have now identified by two-hybrid experiments Hif1 as both a Hat1- and a histone H4-interacting protein. These interactions were dependent on HAT2, indicating a mediating role for Hat2. Biochemical fractionation and co-immunoprecipitation assays demonstrated that Hi…
Rare examples of diphenoxido-bridged trinuclear Ni II 2 Fe III complexes with a reduced salen type Schiff base ligand: Structures and magnetic proper…
2017
Abstract Three new trinuclear hetero-metallic complexes, [(NiLR)2Fe(N3)3] (1), [(NiLR(H2O))2Fe(C6H5CH2CO2)2]·(HSO4) (2) and [(NiLR(H2O))2Fe(C6H5CO2)2]·(HSO4)·(H2O)·(CH2Cl2) (3) have been synthesized using [NiLR] as a “metalloligand” (where H2LR = N,N′-bis(2-hydroxybenzyl)-1,3-propanediamine). All complexes have been characterized by elemental analysis, spectroscopic methods, single crystal XRD and magnetic study. In the angular trinuclear units of 1, the two terminals [NiLR] coordinate through double phenoxido bridges to the central FeIII ion which is penta-coordinated having terminally coordinated azide ion. The two terminal NiII centers are connected to each other and also to neighbouring…
Formation of a dinuclear and a trinuclear Ni(II) complex on slight variation of experimental conditions: Structural analysis and magnetic properties
2017
Abstract A diphenoxido bridged dinuclear Ni(II) complex [Ni2L2(NO2)2] (1) and a μ2 and μ3-phenoxido, μ3-hydroxido, and μ2-nitrito (1κO:2κN) bridged trinuclear Ni(II) complex [Ni3L3(OH)(NO2)]·ClO4 (2), have been synthesized using a tridentate reduced Schiff base ligand HL (HL = 2-[(2-dimethylamino-ethylamino)-methyl]-phenol). Both complexes were characterized by X-ray structure determination and variable-temperature magnetic susceptibility measurements. In both complexes the nickel atoms are six-coordinated with a distorted octahedral environment. The interesting feature of the trimeric complex 2 is that the three mononuclear units are assembled around a μ3-hydroxido ion in such a way that t…
Double azido/cyanato bridged copper(II) dimers incorporating tridentate nitrogen donors Schiff base: Structure, EPR and magnetic studies
2015
Abstract A neutral tridentate nitrogen donor Schiff base ligand L (L = (E)-N-(phenyl(pyridin-2-yl)methylene)-2-(pyridin-2-yl)ethanamine) has been synthesized and characterized by spectroscopic techniques, and employed to synthesize two new μ1,1-azido/cyanato bridged dinuclear copper(II) complexes, [Cu(L)(μ1,1-N3)(ClO4)]2 (1) and [Cu(L)(μ1,1-NCO)(ClO4)]2 (2). Both compounds have been spectroscopically and structurally characterized. Structural investigation reveals centro-symmetric nature of the complexes in which the center of inversion lies at the midpoint of the two copper(II) ions. The metal ions display distorted octahedral geometry. The tridentate neutral ligand L coordinates the metal…
Ethylene homo- and copolymerization catalyzed by vanadium, zirconium, and titanium complexes having potentially tridentate Schiff base ligands
2021
Abstract New potentially tridentate Schiff base ligands, 2-[({4-[(3-N,N-dimethylamino)propyl] phenyl}imino)methyl]-4,6-di-tert-butylphenol (L1H) and 2-[{2-(N-phenyl-N-methylaminomethyl)-phenylimino}-methyl]-4,6-di-tert-butylophenol (L2H) were prepared and after deprotonation they were reacted with VOCl3 or MCl4 (where M = Zr or Ti) to produce corresponding complexes (L1-V, L2-V, L1-Zr, L2-Ti) with good yields. All new compounds were characterized by the 1H and 13C NMR as well as FTIR spectroscopic methods. Upon activation with Et2AlCl or EtAlCl2, both the vanadium complexes exhibited exceptionally high catalytic activities in the ethylene polymerization (up to 69,000 kg/(molV⋅h) for L1-V an…
Mononuclear Fe(III) and tetranuclear [Fe(III)Gd(III)]2 complexes with a Schiff-base ligand derived from the o-vanillin: Synthesis, crystal structures…
2011
The mononuclear high-spin iron(III) complexes [Fe(3-MeOsalpn)Cl(H 2 O)] ( 1 ) and [Fe(3-MeOsalpn)(NCS)(H 2 O)]·0.5CH 3 CN ( 2 ) and the tetranuclear oxo-bridged compound [{Fe(3-MeOsalpn)Gd(NO 3 ) 3 } 2 (μ-O)]·CH 3 CN ( 3 ) [3-MeOsalpn 2− = N , N ′-propylenebis(3-methoxysalicylideneiminate)] have been prepared and magneto-structurally characterised. The iron(III) ion in 1 and 2 is six-coordinated in a somewhat distorted octahedral surrounding with the two phenolate-oxygens and two imine-nitrogens from the Schiff-base building the equatorial plane and a water ( 1 and 2 ) and a chloro ( 1 )/thiocyanate-nitrogen ( 2 ) in the axial positions. The neutral mononuclear units of 1 and 2 are assemb…
Hexanuclear NiII4LnIII2 Complexes with SMM Behavior at Zero Field for Ln = Tb, Dy, Ho
2020
A mononuclear Ni(II) complex, [NiL2]·2H2O, was prepared by the reaction of a N2O2 donor monocondensed Schiff base ligand, 2-((3-aminopropylimino)methyl)-6-methoxyphenol (HL), with NiCl2·6H2O. The reaction of this complex with NiCl2·6H2O and LnCl3·6H2O (Ln = Gd, Tb, Dy, Ho) in a 1:1:1 molar ratio leads to four hexanuclear Ni4Ln2 complexes formulated as [{(NiL)2Gd}2(μ2-Cl)2(μ3-OH)4(OH2)4]Cl4·CH3CN·H2O (1), [{(NiL)2Tb}2(μ2-Cl)2Cl2(μ3-OH)4(OH2)2]Cl2·12H2O (2), [{(NiL)2Dy}2(μ2-Cl)2Cl2(μ3-OH)4(OH2)2]Cl2·16H2O (3), and [{(NiL)2Ho}2(μ2-Cl)2(μ3-OH)4(OH2)4]Cl4·CH3CN·1.8H2O (4). The Ln(III) centers are octacoordinated with a triangular-dodecahedral geometry, and the geometries around the Ni(II) center…
Synthesis, X-ray crystal structure and magnetic study of a novel μ2-1,1-azido bridged dimeric copper(II) complex
2007
Abstract A new azido derivative of tridentate Schiff base copper(II) complex has been synthesized and characterized. X-ray single crystal structure analysis reveals that the complex [Cu2L2(N3)2(NO3)2] (1), containing 1-(N-pyridylimino)-3-aminopropane (L) as co-ligand, is a dimer in which copper(II) ions are bridged by two azido groups in end-on fashion. The coordination environment around copper(II) is distorted octahedral which is rarely observed among these types of azido bridged copper(II) dimers. Three among the four coordination sites of the basal plane of the octahedron are occupied by the nitrogen atoms of the Schiff base and the fourth site is occupied by a nitrogen atom of a μ2-1,1…