Search results for "Odds"

showing 10 items of 1327 documents

Predicting resistant etiology in hospitalized patients with blood cultures positive for Gram-negative bacilli

2018

Abstract Objective To develop a risk-scoring tool to predict multidrug-resistant (MDR) etiology in patients with bloodstream infections (BSI) caused by Gram-negative bacilli (GNB). Methods A prospective multicenter study analyzed patients with BSI hospitalized in 31 Internal Medicine wards in Italy from March 2012 to December 2012. Patients with BSI caused by MDR-GNB (non-susceptible to at least one agent in three antimicrobial categories) were compared to those with BSI due to susceptible GNB. A logistic regression to identify predictive factors of MDR-GNB was performed and the odds ratio (OR) were calculated. A score to predict the risk of MDR was developed. Results Of 533 BSI episodes, 2…

Male0301 basic medicineMultivariate analysisGram-negative bacilliHospitalized patientsLogistic regressionLikelihood ratios in diagnostic testingRisk FactorsDrug Resistance Multiple BacterialMedicineAge FactorMultidrug-resistantProspective StudiesMultivariate AnalysiAged 80 and overAge FactorsAnti-Bacterial AgentsHospitalizationItalyBloodstream infections; Gram-negative bacilli; Multidrug-resistantBloodstream infections; Gram-negative bacilli; Multidrug-resistant; Internal MedicineFemaleSettore SECS-S/01 - StatisticaHumanmedicine.medical_specialtyLogistic Model030106 microbiologyBloodstream infection03 medical and health sciencesInternal medicineAnti-Bacterial AgentGram-Negative BacteriaGram-Negative Bacterial InfectionInternal MedicineHumansAgedbusiness.industryRisk FactorGram negative bacilliOdds ratiomedicine.diseaseProspective StudieLogistic ModelsROC CurveBlood CultureBacteremiaMultivariate AnalysisEtiologyBloodstream infectionsGram-Negative Bacterial Infectionsbusiness
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Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR…

2017

BACKGROUND: There is increasing evidence that metastatic colorectal cancer (mCRC) is a genetically heterogeneous disease and that tumours arising from different sides of the colon (left versus right) have different clinical outcomes. Furthermore, previous analyses comparing the activity of different classes of targeted agents in patients with KRAS wild-type (wt) or RAS wt mCRC suggest that primary tumour location (side), might be both prognostic and predictive for clinical outcome. METHODS: This retrospective analysis investigated the prognostic and predictive influence of the localization of the primary tumour in patients with unresectable RAS wt mCRC included in six randomized trials (CRY…

Male0301 basic medicineOncologyColorectal cancermedicine.medical_treatmentCetuximabmedicine.disease_causeEGFR Antibody0302 clinical medicineAntineoplastic Agents ImmunologicalNeoplasias ColorrectaisMedicineNeoplasm MetastasisRandomized Controlled Trials as Topicpredictive valuePanitumumabHazard ratiotumour sideAntibodies MonoclonalHematologyPrognosisChemotherapy regimenErbB ReceptorsBevacizumabTreatment OutcomeOncology030220 oncology & carcinogenesisFemaleKRASColorectal Neoplasmsmedicine.drugmedicine.medical_specialtyBevacizumabcolorectal cancerGenes ras03 medical and health sciencesAnticorpos MonoclonaisInternal medicineHumansChemotherapybusiness.industryAntineoplásicos ImunológicosOdds ratiomedicine.diseaserandomised trial030104 developmental biologyGenes rasHuman medicinebusinessprognosticanti-EGFR treatment
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Cross-sectional associations between angiotensin-converting enzyme inhibitor use and cancer diagnosis in US adults

2020

The objective of the present study was to investigate the association between angiotensin-converting enzyme (ACE) inhibitor use and cancer incidence (overall, and breast, prostate, and colorectal cancers specifically) in a large representative sample of US adults. Cross-sectional data on cancer diagnosis, timing of cancer diagnosis, ACE inhibitor use, and other characteristics were extracted from 49 512 adults aged ≥ 20 years participating in the National Health and Nutrition Examination Survey (1999–2016). Multivariable-logistic and propensity score matching (PSM) regressions examined the relationship between pre-diagnosis use of ACE inhibitors and diagnosis of all cancers, and breast, pro…

Male0301 basic medicineOncologyEpidemiology[SDV]Life Sciences [q-bio]Angiotensin-Converting Enzyme InhibitorsAngiotensin-converting enzyme inhibitors Cancer · Epidemiology NHANES · ObservationalProstate cancer0302 clinical medicineRisk FactorsSurveys and QuestionnairesObservationalCancerAged 80 and over2. Zero hungerbiologyIncidenceGeneral MedicineMiddle Aged3. Good health030220 oncology & carcinogenesisFemaleColorectal Neoplasmsmedicine.drugAdultmedicine.medical_specialtyNational Health and Nutrition Examination SurveyBreast NeoplasmsGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesInternal medicinemedicineNHANESHumansAgedbusiness.industryProstatic NeoplasmsCancerAngiotensin-converting enzymeOdds ratioAngiotensin-converting enzyme inhibitors Cancer Epidemiology NHANES Observationalmedicine.diseaseUnited StatesCross-Sectional StudiesLogistic Models030104 developmental biologyPropensity score matchingACE inhibitorbiology.proteinbusinessBody mass indexClinical and Experimental Medicine
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Childhood adherence to a potentially healthy and sustainable Nordic diet and later overweight: The Norwegian Mother, Father and Child Cohort Study (M…

2020

Abstract The New Nordic Diet (NND) is a potentially healthy and sustainable dietary pattern represented by locally available and traditionally consumed foods in the Northern countries. The diet has been commonly examined in adult populations, but less is known regarding its potential associations with overweight/obesity in children. We have previously developed child diet scores measuring compliance to the NND at child age 6 and 18 months and 3 and 7 years. In this study, we aimed to describe child and maternal characteristics and assess potential associations between the age‐specific diet scores and child overweight at 8 years. This study is based on the Norwegian Mother, Father and Child …

Male0301 basic medicinePediatric ObesityOverweightLogistic regressionCohort StudiesFathers0302 clinical medicine030212 general & internal medicineMoBaChildlcsh:RC620-627Nutrition and DieteticsNorwaylcsh:RJ1-570Obstetrics and Gynecologybirth cohortchild nutritionlcsh:Nutritional diseases. Deficiency diseasesMoBa MBRNlanguageOriginal ArticleFemalemedicine.symptomchildhood obesityCohort studyAdultdietary patternsMothersNorwegianlcsh:Gynecology and obstetricsChildhood obesityOddsVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciencesmedicineHumanslcsh:RG1-991030109 nutrition & dieteticsbusiness.industrybarker hypothesisPublic Health Environmental and Occupational HealthInfantlcsh:PediatricsOriginal ArticlesOdds ratioOverweightMBRNmedicine.diseaseObesitylanguage.human_languageDietPediatrics Perinatology and Child HealthbusinessDemographyMaternal & Child Nutrition
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Fruit and vegetable consumption in Europe according to gender, educational attainment and regional affiliation—A cross-sectional study in 21 European…

2020

Objective The purpose of the present study was to examine fruit and vegetable consumption according to gender, educational attainment and regional affiliation in Europe. Design Cross-sectional study. Setting 21 European countries. Participants 37 672 adults participating in the 7th round of the European Social Survey. Main outcome measures Fruit and vegetable consumption was measured using two single frequency questions. Responses were dichotomized into low (<once a day) and high (≥once a day) consumption. The association between consumption of fruit and vegetables and gender, educational level, regional affiliation was examined using logistic regression analyses. Results Overall, females s…

Male0301 basic medicinePhysiologyCross-sectional studySocial SciencesLogistic regressionGeographical LocationsMathematical and Statistical TechniquesEndocrinology0302 clinical medicineSociologyVegetablesMedicine and Health SciencesEurope Eastern030212 general & internal medicineHealth Systems StrengtheningMultidisciplinaryStatisticsQREukaryotaRegression analysisPlantsResearch AssessmentMiddle AgedType 2 DiabetesEuropean Social SurveyPeer reviewEuropeGeographyPhysical SciencesRegression AnalysisEducational StatusMedicineFemaleResearch ArticleSystematic ReviewsEndocrine DisordersScienceResearch and Analysis MethodsDiet SurveysEducationFruitsOddsVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciencesSex FactorsDiabetes MellitusHumansStatistical MethodsEducational AttainmentConsumption (economics)Health Care Policy030109 nutrition & dieteticsOrganismsFood ConsumptionBiology and Life SciencesEducational attainmentDietHealth CareCross-Sectional StudiesDiet and Type 2 DiabetesMetabolic DisordersFruitPeople and PlacesPhysiological ProcessesMathematicsDemographyPLOS ONE
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Hyperlipidaemia prevalence and cholesterol control in obstructive sleep apnoea: Data from the European sleep apnea database (ESADA)

2019

Abstract.Gunduz C, Basoglu OK, Hedner J, et al; onbehalf of the European Sleep Apnoea Databasecollaborators (Biruni University; Ege University;Gothenburg University; Sahlgrenska UniversityHospital; University of Palermo; CNR Institute ofBiomedicine and Molecular Immunology; St. AdolfStift; Hospital de Santa Maria; University of Crete;Antoine-Beclere Hospital; G. PapanikolaouHospital; Institute of Tuberculosis and LungDiseases; University Hospital Brno; St. Ann’sUniversity Hospital; Universite ́ Grenoble Alpes)Hyperlipidaemia prevalence and cholesterolcontrol in obstructive sleep apnoea: Data from theEuropean sleep apnea database (ESADA).J InternMed2019;286: 676–688.Background and objective.…

Male0301 basic medicine[SDV]Life Sciences [q-bio]PolysomnographyHyperlipidemiasSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologycomputer.software_genre03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusPrevalenceInternal MedicineHumansMedicinecholesterol ; hyperlipidaemia ; hypoxia ; obesity ; sleep apnoea.ObesitySleep Apnea ObstructiveDatabasehyperlipidaemiahypoxiabusiness.industryConfoundingcholesterolSleep apneaOdds ratioMiddle Agedmedicine.diseaseObesityrespiratory tract diseases[SDV] Life Sciences [q-bio]EuropeCross-Sectional Studies030104 developmental biologyQuartileCardiovascular DiseasesCohortFemaleHuman medicinebusinesssleep apnoeaBody mass indexcomputer
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The relationship between the dietary inflammatory index and prevalence of radiographic symptomatic osteoarthritis: data from the Osteoarthritis Initi…

2017

Purpose: To investigate whether higher dietary inflammatory index (DII ® ) scores were associated with higher prevalence of radiographic symptomatic knee osteoarthritis in a large cohort of North American people from the Osteoarthritis Initiative database. Methods: A total of 4358 community-dwelling participants (2527 females; mean age 61.2 years) from the Osteoarthritis Initiative were identified. DII ® scores were calculated using the validated Block Brief 2000 Food-Frequency Questionnaire and scores were categorized into quartiles. Knee radiographic symptomatic osteoarthritis was diagnosed clinically and radiologically. The strength of association between divided into quartiles (DII ® ) …

Male0301 basic medicinemedicine.medical_specialtyDatabases FactualPrevalenceMedicine (miscellaneous)Arthritis030209 endocrinology & metabolismOsteoarthritisLogistic regressionDietary inflammatory indexArticleCohort Studies03 medical and health sciences0302 clinical medicineRisk FactorsSurveys and QuestionnairesInternal medicinePrevalencemedicineHumansddc:616Inflammation030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryOdds ratioMiddle AgedOsteoarthritis Kneemedicine.diseaseConfidence intervalDietRadiographyKnee osteoarthritis · Dietary inflammatory index · InflammationQuartileDietary inflammatory index; Inflammation; Knee osteoarthritisFemaleKnee osteoarthritisbusinessCohort studyEuropean Journal of Nutrition
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Effect of antiviral treatment in older patients hospitalized with confirmed influenza

2019

Abstract Seasonal influenza causes significant morbidity and mortality in people aged ≥65 years. Antiviral treatment can reduce complications and disease severity. The objective of this study was to investigate the effect of antiviral treatment in patients aged ≥65 years hospitalized with confirmed influenza in preventing intensive care unit (ICU) admission or death. A retrospective cohort study was carried out in 20 hospitals from seven Spanish regions during 2013–2015 in patients aged ≥65 years. Hospitalized cases of laboratory-confirmed influenza were selected. To assess the association between antiviral treatment and ICU admission or death, the adjusted odds ratios (aOR) and their 95% c…

Male0301 basic medicinemedicine.medical_specialtyHospitalized patients030106 microbiologyLogistic regressionAntiviral AgentsTime-to-Treatmentlaw.invention03 medical and health sciencesOseltamivirOlder patientsAdrenal Cortex HormoneslawVirologyInternal medicineInfluenza HumanHumansMedicineAntiviral treatmentAgedRetrospective StudiesPharmacologybusiness.industryRetrospective cohort studyOdds ratioIntensive care unitConfidence intervalHospitalizationIntensive Care UnitsTreatment Outcome030104 developmental biologyFemalebusinessAntiviral Research
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Enteral tube feeding and mortality in hospitalized older patients: A multicenter longitudinal study

2020

Background &amp; aims: The literature regarding enteral nutrition and mortality in older frail people is limited and still conflicting. Moreover, the potential role of comprehensive geriatric assessment is poorly explored. We therefore aimed to investigate whether the Multidimensional Prognostic Index (MPI), an established tool that assesses measures of frailty and predicts mortality, may help physicians in identifying patients in whom ETF (enteral tube feeding) is effective in terms of reduced mortality. Methods: Observational, longitudinal, multicenter study with one year of follow-up. Data regarding ETF were recorded through medical records. A standardized comprehensive geriatric assessm…

Male0301 basic medicinemedicine.medical_specialtyLongitudinal studyPrognosis.030209 endocrinology & metabolismCritical Care and Intensive Care MedicineHospital03 medical and health sciences0302 clinical medicineMultidimensional prognostic indexOdds RatiomedicineRisk of mortalityHumansLongitudinal StudiesMortalityAgedEnteral Tube FeedingAged 80 and overInpatients030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryMedical recordAustraliaOdds ratioConfidence intervalEuropeParenteral nutritionEmergency medicinePropensity score matchingFemaleEnteral nutritionbusinessClinical Nutrition
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Mild cognitive impairment in Parkinson’s disease: the Parkinson’s disease cognitive study (PACOS)

2018

Approximately 30% of Parkinson's disease (PD) patients show impaired cognitive performance, which is suggestive of Mild Cognitive Impairment (MCI), representing a predictor of dementia, especially when present at diagnosis. The objective of the study was to evaluate the frequency and clinical predictors of MCI in a large hospital-based cohort of PD patients. We collected cross-sectional data from the Parkinson's disease cognitive impairment study (PACOS), a multicenter study involving two Movement Disorder centers, which are located in south Italy. The PD subjects were diagnosed according to the UK Brain Bank criteria and they underwent an extensive neuropsychological assessment. PD-MCI was…

Male0301 basic medicinemedicine.medical_specialtyNeurologyParkinson's diseaseEpidemiologyParkinson's diseaseNeuropsychological TestsLogistic regressionSeverity of Illness Index03 medical and health sciences0302 clinical medicineInternal medicinemental disordersEpidemiologyOdds RatioPrevalenceHumansMedicineDementiaCognitive DysfunctionParkinsonâ s diseaseEffects of sleep deprivation on cognitive performanceNeuropsychological assessmentAge of OnsetCognitive impairment; Epidemiology; Parkinson’s disease; Prevalence; Neurology; Neurology (clinical)AgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryParkinson Diseasemedicine.diseasenervous system diseasesCross-Sectional StudiesCognitive impairment030104 developmental biologyNeurologyMultivariate AnalysisCohortEducational StatusSettore MED/26 - NeurologiaFemaleAmnesiaNeurology (clinical)businesshuman activities030217 neurology & neurosurgeryJournal of Neurology
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