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2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents.

2016

Increasing prevalence of hypertension (HTN) in children and adolescents has become a significant public health issue driving a considerable amount of research. Aspects discussed in this document include advances in the definition of HTN in 16 year or older, clinical significance of isolated systolic HTN in youth, the importance of out of office and central blood pressure measurement, new risk factors for HTN, methods to assess vascular phenotypes, clustering of cardiovascular risk factors and treatment strategies among others. The recommendations of the present document synthesize a considerable amount of scientific data and clinical experience and represent the best clinical wisdom upon wh…

Gestational exposure to cocaine alters cocaine reward

2006

Exposure of the developing foetus to drugs of abuse during pregnancy may lead to persistent abnormalities of brain systems involved in drug addiction. Mice prenatally exposed to cocaine (25 mg/kg), physiological saline or non-treated during the last 7 days of pregnancy were evaluated in adulthood for the rewarding properties of cocaine (3, 25 and 50 mg/kg), using the conditioned place preference procedure. Dams treated with physiological saline gained significantly less weight over the course of gestation than controls; no other differences were observed in the maternal and offspring data. All the animals developed preference to 3 and 25 mg/kg of cocaine, but those treated prenatally with c…

HPTLC and GC-MS for separation and identification of eugenol in plants

2007

Samples of clove, nutmeg, and cinnamon have been extracted by maceration with ethanol for 24 h and with aqueous ethanol 48 h. Rhizomes of herb bennet ( Geum urbanum ) and calamus ( Aconum calamus ) and roots of valerian ( Valeriana officinalis ) have been subjected to aqueous hydrolysis then extraction with dichloromethane. The active principles from the samples were separated on silica gel HPTLC plates, with pure (standard) and dental (pharmaceutical) eugenol, using n -heptane-ethyl acetate 60+40 ( v / v ) as mobile phase. After development the components were visualized in UV light at λ = 254 nm. The presence of eugenol was confirmed by GC-MS.

Beneficium e iniuria. Rappresentazioni del dono e dell’offesa nel De beneficiis di Seneca

2018

Teratogenicity and Developmental Toxicity of Herbal Products

2017

Developmental toxicology and research in teratogenicity focus on xenobiotic substances that damage embryos and fetuses and lead to death, growth retardation, and/or malformation of offspring. While considerable information has been acquired about synthetic drugs and environmental xenobiotics, much less is known about the teratogenicity of herbal products. In this chapter we report on some major topics of developmental toxicity and teratogenicity, and discuss the safety of a few selected medicinal herbs in this context, i.e., Artemisia annua L., Caulophyllum thalictroides (L.) Michx., Echinacea spec,. Glycyrrhiza spec., herbs derived from Chinese medicine, Hypericum perforatum L., Panax gins…

A Multi-Criteria Decision Support System for Strategic Planning at the Swiss Forest Enterprise Level: Coping With Climate Change and Shifting Demands…

2021

Sustainable forest management plays a key role for forest biodiversity and the provisioning of ecosystem services (BES), including the important service of carbon sequestration for climate change mitigation. Forest managers, however, find themselves in the increasingly complex planning situation to balance the often conflicting demands in BES. To cope with this situation, a prototype of a decision support system (DSS) for strategic (long-term) planning at the forest enterprise level was developed in the present project. The DSS was applied at three case study enterprises (CSEs) in Northern Switzerland, two lowland and one higher-elevation enterprise, for a 50-year time horizon (2010 to 2060…

Workshop on Competencies for the Globalization of Information Systems in Knowledge-Intensive Settings

2010

Software development has become a global task for the past decades. Outsourcing and offshoring solutions have been discussed frequently, in both research and in industry. Export is the main driver for a society’s and corresponding individual’s wealth. As more and more organizations apply outsourcing and offshoring practices, new ways have to be found to compete in this rapidly changing environment. Additionally, the digital divide is becoming a central issue, determining the relation of developed and developing countries.

"Huumeet molemmin puolin pöytää"

2001

Kauppakeskuksen avajaispäivä - esityksiä ja rituaaleja : esitysten ja rituaalien purku Erving Goffmanin teorian ja radiodokumentin keinoin

2004

Sisäinen markkinointi johtamisena : tapaustutkimus konepajateollisuuden projektiorganisaatiosta

2009

The objective of this study was to increase the understanding of the management of internal marketing. The theoretical objective was to specify the mutual relation of the concepts of internal marketing and management. On the basis of an analysis of the two concepts and of research literature, a managerial model of the management of internal marketing was built as a theoretical frame of reference.The empirical part of the study examined how the members of the personnel in the case organization built their perception of internal marketing management in their mutual interaction on the basis of their experiences and their feelings. On the basis of the frame of reference model and the empirical …