Search results for "Olio"
showing 10 items of 630 documents
Riemergenza del poliovirus ed implicazioni per la vaccinazione anti-poliovirus in Italia
2014
Nel 1988, l’Organizzazione mondiale della Sanità (OMS) ha approvato il piano di eradicazione mondiale della poliomielite con l’obiettivo di annullare la circolazione del virus a partire dall’anno 2000. Tale target, per motivi economici, organizzativi, culturali, bellici e financo religiosi, è stato successivamente spostato in avanti negli anni fino a giungere attualmente al 2015. A seguito di questo impegno, negli anni si è registrata una riduzione dell’incidenza di poliomielite di oltre il 99%, passando dai 350.000 casi annui di polio paralitica documentati nel 1988 in 125 paesi, alle poche centinaia di casi riscontrati nel 2013 sia negli ultimi 3 paesi endemici (Nigeria, Afghanistan, Paki…
Forecasting the Size Premium Over Different Horizons
2011
In this paper, we provide evidence that the small stock premium is predictable both in-sample and out-of-sample through the use of a set of lagged macroeconomic variables. We find that it is possible to forecast the size premium over time horizons that range from one month to one year. We demonstrate that the predictability of the size premium allows a portfolio manager to generate an economically and statistically significant active alpha.
Selezione di Portafoglio e Metaeuristiche
2013
Il problema della selezione del portafoglio (PSP) ha come obiettivo quello di determinare, disponendo di un dato insieme di titoli, il portafoglio che minimizza una misura di rischio per un dato livello di rendimento minimo richiesto. Sebbene nella sua formulazione originaria il PSP può essere risolto utilizzando algoritmi di programmazione lineare o quadratica, l'inclusione di ulteriori vincoli ed obiettivi rende il problema computazionalmente difficile. Nel presente lavoro viene proposto un approccio metaeuristico al PSP in cui vengono considerate diverse misure di distanza tra i portafogli della frontiera efficiente (Mean-Variance) ed il portafoglio ottimo che si ottiene in corrispondenz…
A Perturbation Approach to Continuous-Time Portfolio Selection Under Stochastic Investment Opportunities
2013
This paper studies portfolio selection in continuous-time models with stochastic investment opportunities. We consider asset allocation problems where preferences are specified as power utility derived from terminal wealth as well as consumption-savings problems with recursive utility Epstein-Zin preferences. The paper approximates the associated dynamic programming problem by perturbing the coefficients of the stochastic dynamics. We represent the Hamilton-Jacobi-Bellman equation as a series of partial differential equations that can be solved iteratively in closed-form through computer algebra software, at any desired accuracy.
The knowledge of women with epilepsy on motherhood
2017
Wstęp: Padaczka jest jedną z najczęstszych chorób neurologicznych. Na całym świecie cierpi na nią ok. 50 mln osób, z czego połowa to kobiety. Pomimo że ciąża w przebiegu epilepsji zaliczana jest do ciąż wysokiego ryzyka, na podstawie wielu obserwacji przyjmuje się, że szansa urodzenia zdrowego dziecka przez kobietę z padaczką wynosi ponad 90%, ale ryzyko wystąpienia wad wrodzonych jest 2–3-krotnie wyższe niż w przypadku ciąży u kobiety zdrowej. Wynika to głównie z faktu stosowania leków przeciwpadaczkowych. Materiał i metody: Badaniami objęto 139 kobiet chorych na padaczkę, w wieku od 18 do 40 lat, będących pod opieką poradni neurologicznych na terenie województwa śląskiego. Badania przepro…
Strategising IT service management through ITIL implementation: model and empirical test
2015
Research on the Information Technology Infrastructure Library (ITIL) lacks appropriate theories and models that capture the distinct characteristics and implications of the ITIL implementation practice. The purpose of this study is to close this gap. Based on a literature review, we develop and empirically validate a theoretical model: the ITIL Implementation Project Model. The model includes significant antecedents, which provide a foundation upon which an effective ITIL implementation project can be built, as well as the pertinent effects of implementing ITIL. The results contribute to the current research stream on the strategising of IT service management as well as to an improved under…
IMPLEMENTING A VALUE ASSESSMENT TOOL FOR SERVICE INNOVATION IDEAS
2010
There has not been much discussion of how firms may assess the value of service innovation projects ex-ante in the extant research literature. This paper theoretically derives a value assessment tool for service innovation ideas called QSI (tool for pre-Qualification of Service Innovation projects). Thereafter QSI is implemented in three firms and it is explored to what degree the implementation improved managerial decision making on service innovation projects and investments. The findings indicated that the implementation of QSI had effects both in a portfolio management and a project management perspective. From a portfolio management point of view deployment of QSI improved the particip…
Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells
2019
Abstract Background The multidrug resistance (MDR) phenotype encounters a major challenge to the success of established chemotherapy in cancer patients. We hypothesized that cytotoxic medicinal plants with novel phytochemicals can overcome MDR and kill MDR-cells with similar efficacy as drug sensitive cells. Purpose We evaluated plant extracts from an unexplored ecosystem in Egypt with unusual climate and nutrient conditions for their activity against sensitive and multidrug-resistant cancer cell lines. Material and methods/study design Methylene chloride: methanol (1:1) and methanol: H2O (7:3) extracts of 40 plants were prepared resulting in a sum of 76 fraction containing compounds with v…
A proposal for sorting a projects portfolio through the ELECTRE TRI method focused on the European strategy
2019
In recent years, the partnerships between private companies and public organizations are becoming key elements for improving local development, territorial competitiveness, and delivering innovation. These collaborations are widely promoted by the European Framework Programme for Research and Innovation thanks to the provision of several instruments, such as Horizon 2020. In this context, competitiveness's improvement of the territory employing research and innovation actions is supported by the technological districts. In Sicily, the AgroBioPesca district has attempted a strategic action named "Call for ideas" in order to design its own roadmap for research and innovation in the agri-food …
Nordic Cooperation in the Nuclear Safety Sector: High, Low, or Differentiated Integration?
2020
Nordic cooperation has been depicted as eroding due to the increased importance of EU-related cooperation and integration. However, scholars propose that longstanding Nordic networks, grounded in professions and located in the state administration, may prove to be more robust toward external changes. This article discusses this proposal by looking at Nordic cooperation between the national radiation protection and nuclear safety authorities in Iceland, Denmark, Norway, Sweden, and Finland. The article maps behavioural perceptions of agency staff based on a dataset of 37 interviews to illustrate if the cooperation between the Nordic authorities is characterized by high integration, low integ…