Search results for "Ones"
showing 10 items of 7243 documents
Sociedades fragiles
2001
Economía criminal y terror
2001
El honor de la sociedad civil israeli
2002
Antiamericanismo
2002
The Effects of Orography on the Extratropical Transition of Tropical Cyclones: A Case Study of Typhoon Sinlaku (2008)
2018
Abstract Extratropical transition (ET) can cause high-impact weather in midlatitude regions and therefore constitutes an ongoing threat at the end of a tropical cyclone’s (TC) life cycle. Most of the ET events occur over the ocean, but some TCs recurve and undergo ET along coastal regions; however, the latter category is less investigated. Typhoon Sinlaku (2008), for example, underwent ET along the southern coast of Japan. It was one of the typhoons that occurred during the T-PARC field campaign, providing unprecedented high-resolution observational data. Sinlaku is therefore an excellent case to investigate the impact of a coastal region, and in particular orography, on the evolution of ET…
Temperature-related mortality impacts under and beyond Paris Agreement climate change scenarios.
2018
The Paris Agreement binds all nations to undertake ambitious efforts to combat climate change, with the commitment to hold warming well below 2 degrees C in global mean temperature (GMT), relative to pre-industrial levels, and to pursue efforts to limit warming to 1.5 degrees C. The 1.5 degrees C limit constitutes an ambitious goal for which greater evidence on its benefits for health would help guide policy and potentially increase the motivation for action. Here we contribute to this gap with an assessment on the potential health benefits, in terms of reductions in temperature-related mortality, derived from the compliance to the agreed temperature targets, compared to more extreme warmin…
Regionalizing Rainfall at Very High Resolution over La Réunion Island: A Case Study for Tropical Cyclone Ando
2016
AbstractEnsemble simulations of Tropical Cyclone (TC) Ando (31 December 2000–9 January 2001) are performed over the southwest Indian Ocean using the nonhydrostatic WRF Model. Nested domains centered over the island of La Réunion allow for the simulation of local rainfall amounts associated with TC Ando at very high resolution (680-m grid spacing). The model is forced by and nudged toward ERA-Interim during the first (1–6) day(s) of the TC’s life cycle. The nudging ends at various dates to constrain either the whole life cycle or only parts of it.As expected, results show weakened member dispersion, as the relaxation lasts longer, with more members producing similar cyclone tracks and intens…
PACAP induces bradycardia in guinea-pig heart by stimulation of atrial cholinergic neurones
1996
Based on previous studies which indicated that pituitary adenylate cyclase activating peptide (PACAP) acts as a positive inotropic and chronotropic substance in different species via the cAMP signal transduction pathway, the objective of the present work was to investigate cAMP-regulated myocardial key proteins in response to PACAP in isolated ventricular cells of the guinea pig. Surprisingly, the two molecular forms of PACAP, PACAP(1-27) and PACAP(1-38), showed no effect on intracellular cAMP-levels, L-type Ca2+ channel current or phosphorylation of troponin inhibitor (TnI) and phospholamban (PLB). Additionally, inotropy of isolated guinea-pig ventricular strips was not affected by the neu…
Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon
2013
The aim of this study was to analyze whether arginine vasopressin (AVP) may be considered a modulator of intestinal motility. In this view, we evaluated, in vitro, the effects induced by exogenous administration of AVP on the contractility of mouse distal colon, the subtype(s) of receptor(s) activated and the action mechanism. Isometric recordings were performed on longitudinal and circular muscle strips of mouse distal colon. AVP (0.001 nM-100 nM) caused concentration-dependent contractile effects only on the longitudinal muscle, antagonized by the V1 receptor antagonist, V-1880. AVP-induced effect was not modified by tetrodotoxin, atropine and indomethacin. Contractile response to AVP was…
Uveal effusion syndrome complicated by anterior ischemic optic neuropathy
1995
We report on a case of idiopathic uveal effusion syndrome complicated by AION. To our knowledge such an association hasn't been previously described. We suggest that scleral thickening caused obstruction of vortex veins followed by uveal effusion and compression of posterior ciliary arteries within their intrascleral tract, leading to AION. Nevertheless it can't be excluded that AION was the result of mechanical compression on ciliary vessels of optic disc by choroidal detachment. © 1996, Kluwer Academic Publishers. All rights reserved.