Search results for "Online"

Two optimizing procedures for the solution of complex systems of equations: a powerful tool for modelling and simulation of metabolism

2000

Introduction Standard calculations for the evaluation of indirect calorimetry (IC) are based on two-dimensional nonlinear systems of equations. For a more sophisticated evaluation metabolic models can be used, which are described by complex systems of equations. Since the solutions are multidimensional, a concrete result must be selected by means of constraints, using optimizing procedures. These multidimensional optimizations are critical concerning processing time and reproducibility of minimum detection. Methods In order to simulate the status of metabolism of ICU patients on the basis of IC data, a complex model of metabolism was developed. The model was described by a system of equatio…

Introducing Assessment Tools for 21st Century Skills in Finland

2014

The Finnish national interest in the enhancement of 21st century skills has highlighted a need for and interest in developing tools and methods for teaching and assessing such skills. In this chapter, we present and analyze the development process of online assessment tools in the Assessment and Teaching of 21st Century Skills study (ATC21STM) from the Finnish perspective. (The acronym ATC21STM has been globally trademarked. For purposes of simplicity the acronym is presented throughout the chapter as ATC21S.) The development process was implemented according to the guidelines of the international project through four phases, namely concept checks, cognitive laboratories, pilot studies and …

2016

The goal of this article is to present a first list of ethical concerns that may arise from research and personal use of virtual reality (VR) and related technology, and to offer concrete recommendations for minimizing those risks. Many of the recommendations call for focused research initiatives. In the first part of the article, we discuss the relevant evidence from psychology that motivates our concerns. In section 1.1, we cover some of the main results suggesting that one’s environment can influence one’s psychological states, as well as recent work on inducing illusions of embodiment. Then, in section 1.2, we go on to discuss recent evidence indicating that immersion in VR can have psy…

Current research in biotechnology: Exploring the biotech forefront

2019

Abstract Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/regions, and journals. The Web of Science Core Collection online database was searched to retrieve biotechnology articles published since 2017. In total, 12,351 publications were identified and analyzed. Over 8500 institutions contributed to these biotechnology publications, with the top 5 most productive ones scattered over France, China, the United States of America, Spain, and Brazil. Over 140 countries/regions contributed to the biotechnology resear…

Field- and irradiation-induced phenomena in memristive nanomaterials

2016

The breakthrough in electronics and information technology is anticipated by the development of emerging memory and logic devices, artificial neural networks and brain-inspired systems on the basis of memristive nano-materials represented, in a particular case, by a simple 'metal-insulator-metal' (MIM) thin-film structure. The present article is focused on the comparative analysis of MIM devices based on oxides with dominating ionic (ZrOx, HfOx) and covalent (SiOx, GeOx) bonding of various composition and geometry deposited by magnetron sputtering. The studied memristive devices demonstrate reproducible change in their resistance (resistive switching - RS) originated from the formation and …

Domain walls and ising-BLOCH transitions in parametrically driven systems.

2002

Parametrically driven systems sustaining sech solitons are shown to support a new kind of localized state. These structures are walls connecting two regions oscillating in antiphase that form in the parameter domain where the sech soliton is unstable. Depending on the parameter set the oppositely phased domains can be either spatially uniform or patterned. Both chiral (Bloch) and nonchiral (Ising) walls are found, which bifurcate one into the other via an Ising-Bloch transition. While Ising walls are at rest Bloch walls move and may display secondary bifurcations leading to chaotic wall motion.

Numerical Front Propagation Using Kinematical Conservation Laws

2011

We use the newly formulated three-dimensional (3-D) kinematical conservation laws (KCL) to study the propagation of a nonlinear wavefront in a polytropic gas in a uniform state at rest. The 3-D KCL forms an under-determined system of six conservation laws with three involutive constraints, to which we add the energy conservation equation of a weakly nonlinear ray theory. The resulting system of seven conservation laws is only weakly hyperbolic and therefore poses a real challenge in the numerical approximation. We implement a central finite volume scheme with a constrained transport technique for the numerical solution of the system of conservation laws. The results of a numerical experimen…

Adiabatic evolution for systems with infinitely many eigenvalue crossings

1998

International audience; We formulate an adiabatic theorem adapted to models that present an instantaneous eigenvalue experiencing an infinite number of crossings with the rest of the spectrum. We give an upper bound on the leading correction terms with respect to the adiabatic limit. The result requires only differentiability of the considered projector, and some geometric hypothesis on the local behavior of the eigenvalues at the crossings.

Molecular genetics of autosomal dominant retinitis pigmentosa (ADRP): a comprehensive study of 43 Italian families

2005

Retinitis pigmentosa is the most common form of retinal degeneration and is heterogeneous both clinically and genetically. The autosomal dominant forms ( ADRP) can be caused by mutations in 12 different genes. This report describes the first simultaneous mutation analysis of all the known ADRP genes in the same population, represented by 43 Italian families. This analysis allowed the identification of causative mutations in 12 of the families (28% of the total). Seven different mutations were identified, two of which are novel (458delC and 6901C --> T (P2301S), in the CRX and PRPF8 genes, respectively). Several novel polymorphisms leading to amino acid changes in the FSCN2, NRL, IMPDH1, and…

Afternotes on PHM: Harmonic ENO Methods

2003

PHM methods have been used successfully as reconstruction procedures to design high-order Riemann solvers for nonlinear scalar and systems of conservation laws, (see [8], [1], [4]). We introduce a new class of polynomial reconstruction procedures based on the harmonic mean of the absolute values of finite diferences used as difference-limiter, following the original idea used before to design the piecewise hyperbolic method, introduced in [8]. We call those methods ’harmonic ENO methods’, (HENO). Furthermore, we give analytical and numerical evidence of the good behavior of these methods used as reconstruction procedures for the numerical approximation by means of shock-capturing methods fo…