Search results for "Operative"

showing 10 items of 2781 documents

Cerebral haemodynamic changes during propofol-remifentanil or sevoflurane anaesthesia: transcranial Doppler study under bispectral index monitoring

2006

Background. Sevoflurane or propofol–remifentanil-based anaesthetic regimens represent modern techniques for neurosurgical anaesthesia. Nevertheless, there are potential differences related to their activity on the cerebrovascular system. The magnitude of such difference is not completely known. Methods. In total 40 patients, treated for spinal or maxillo-facial disorders, were randomly allocated to either i.v. propofol–remifentanil or inhalational sevoflurane anaesthesia. Transcranial Doppler was used to assess changes in cerebral blood flow velocity, carbon dioxide reactivity, cerebral autoregulation and the bispectral index to assess the depth of anaesthesia. Results. Time-averaged mean f…

MaleUltrasonography Doppler TranscranialHemodynamicsBlood PressurePiperidinesHeart RateMedicineHomeostasisProspective StudiesPropofolUltrasonographyIntraoperativeAdult Anesthetics; Combined; pharmacology Anesthetics; Inhalation; Intravenous; pharmacology Blood Flow Velocity; drug effects Blood Pressure; drug effects Carbon Dioxide; physiology Cerebrovascular Circulation; drug effects Electroencephalography Female Heart Rate; drug effects Homeostasis; drug effects Humans Male Methyl Ethers; pharmacology Middle Aged Monitoring; Intraoperative; methods Piperidines; pharmacology Propofol; pharmacology Prospective Studies Ultrasonography; Doppler; TranscranialCombineddrug effectDopplerElectroencephalographyMiddle AgedAnesthetics CombinedCerebral blood flowInhalationBispectral indexAnesthesiaCerebrovascular CirculationAnesthetics InhalationmethodFemaleIntravenousPropofolAnesthetics IntravenousBlood Flow Velocitymedicine.drugHumanMethyl EthersAdultMonitoringRemifentanilIntravenouTranscranialCerebral autoregulationtranscranial DopplerSevofluranemethodsRemifentanilSevofluranePiperidineMonitoring IntraoperativeHomeostasiHumansAnestheticsbusiness.industryAnestheticCarbon DioxideTranscranial DopplerProspective StudieAnesthesiology and Pain MedicineMethyl Etherdrug effectsphysiologypharmacologybusiness
researchProduct

Outcomes of cataract surgery in diabetic patients: results of the Pan American Collaborative Retina Study Group.

2014

Purpose: This study was designed to evaluate the visual and anatomical outcomes after cataract surgery in diabetic patients with different intraoperative therapeutic strategies. Methods: The research design comprised of a multicentric, retrospective, interventional study conducted at 6 centers in Argentina, Brazil, Costa Rica, Puerto Rico, Spain, and Venezuela. We included 138 diabetic patients with at least 6-month follow-up following phacoemulsification and intraocular lens implantation. Best-corrected visual acuity (BCVA) and central subfield thickness were collected at baseline and at 1-, 2-, 3-, and 6-month follow-up. Of these, 42 cases were not treated with any intraoperative coadjuva…

MaleVascular Endothelial Growth Factor ATriamcinolone acetonideVisual acuitygenetic structuresmedicine.medical_treatmentExtração de catarataVisual AcuityIntraocular lensCuidados intraoperatóriosAngiogenesis InhibitorsTriamcinolonelcsh:OphthalmologyLens Implantation IntraocularDiabetic retinopathyAntibodies monoclonalAged 80 and overGeneral MedicineDiabetic retinopathyMiddle AgedMulticenter studyBevacizumabTreatment OutcomeCataract extractionChemotherapy AdjuvantEstudo multicêntricoIntravitreal InjectionsFemalemedicine.symptommedicine.drugAdultmedicine.medical_specialtyBevacizumabAntibodies Monoclonal HumanizedCataractMacular EdemaIntraoperative careOphthalmologyEdema macularmedicineAnticorpos monoclonaisHumansMacular edemaGlucocorticoidsAgedRetrospective StudiesMacular edemaDiabetic RetinopathyIntraoperative CarePhacoemulsificationbusiness.industryRetinopatia diabéticaPhacoemulsificationCataract surgeryFacoemulsificaçãomedicine.diseaseSurgeryImplante de lente intraocularOphthalmologyLens implantation intraocularlcsh:RE1-994businessFollow-Up StudiesArquivos brasileiros de oftalmologia
researchProduct

Postoperative endophthalmitis incidence after intravitreal therapy: a comparison of two different preoperative antibiotic prophylaxis.

2016

Prevention of postoperative endophthalmitis (POE) is a goal of every ophthalmic procedure and also in intravitreal therapy (IVT). This comparative retrospective study targets whether systemic and topical preoperative antibiotic prophylaxis (PAP) regimen does prevent POE after IVT in a higher rate compared with topical PAP alone. Out of 6111 IVT performed over a period of 103.5 months, in the study group A patients were treated with systemic and topical PAP (2881 IVT), and in the study group B patients were treated only with topical PAP (3230 IVT). Intravitreal drugs were anti-VEGF, triamcinolone and dexamethasone implants. The incidence of POE in group A (1/2881 or 0.035 % per injection) wa…

MaleVascular Endothelial Growth Factor Amedicine.medical_specialtyTriamcinolone acetonideAngiogenesis InhibitorsTriamcinolone AcetonideGroup BDexamethasone03 medical and health sciences0302 clinical medicineEndophthalmitisPostoperative ComplicationsAntibiotic prophylaxiPreoperative CaremedicineHumansEndophthalmitiAntibiotic prophylaxisGlucocorticoidsDexamethasoneAgedRetrospective StudiesAged 80 and overDrug ImplantsEndophthalmitisDose-Response Relationship DrugSettore MED/30 - Malattie Apparato Visivobusiness.industryIncidence (epidemiology)IncidenceIntravitreal therapyRetrospective cohort studyAntibiotic ProphylaxisMiddle Agedmedicine.diseaseSurgeryAnti-Bacterial AgentsOphthalmologyRegimenAnesthesiaIntravitreal Injections030221 ophthalmology & optometryFemalebusiness030217 neurology & neurosurgerymedicine.drugInternational ophthalmology
researchProduct

Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study

2021

Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231…

MaleVascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERinfectious diseases0302 clinical medicine030202 anesthesiologyAnesthesiologyCirugía80 and overProspective StudiesYoung adultChildLungAged 80 and overCOVID-19 ; delay ; SARS-CoV-2 ; surgery ; timingSARS‐CoV‐2 infectionOperativeChild PreschoolPneumonia & InfluenzaInfectionCohort studyHumanmedicine.medical_specialtydelayClinical SciencesSars-cov-2GlobalSurg CollaborativeSettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE03 medical and health sciencesClinical ResearchAnesthesiologyBiodefenseCorrespondence617HumansPULMONARY COMPLICATIONSCRIANÇAS EM IDADE PRÉ-ESCOLARAgedScience & TechnologyCirurgiaPreventionCOVID-19; SARS-CoV-2; delay; surgery; timingInfantOdds ratioPneumoniaProspective StudieClinical research/dk/atira/pure/core/keywords/uob_covid19SurgeryHuman medicine610 Medizin und Gesundheit1109 NeurosciencesInternationalitySettore MED/29 - CHIRURGIA MAXILLOFACCIALESettore MED/18 - CHIRURGIA GENERALECOVID-19; delay; SARS-CoV-2; surgery; timing; Adolescent; Adult; Aged; Aged 80 and over; Child; Child Preschool; Cohort Studies; Female; Humans; Infant; Male; Middle Aged; Prospective Studies; SARS-CoV-2; Surgical Procedures Operative; Time; Young Adult; COVID-19; Internationality; Practice Guidelines as TopicgastroenterologyCohort StudiessurgeryMedicine and Health Sciencestiming030212 general & internal medicineProspective cohort studyMortality rateCOVID-19; delay; SARS-CoV-2; surgery; timingCovid19Middle AgedInfectious DiseasesSurgical Procedures OperativePractice Guidelines as TopicFemalePatient Safetymedicine.symptom6.4 SurgeryLife Sciences & BiomedicineAdult61Adolescent610 Medicine & healthCOVID-19 SARS-CoV-2 delay surgery timingAsymptomaticNOCOVIDSurg CollaborativeTimeVaccine RelatedYoung AdultAll institutes and research themes of the Radboud University Medical CentermedicineMortalitatddc:610MortalityPreschoolLS7_4Surgical Proceduresbusiness.industrySARS-CoV-2NeurosciencesEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical Sciences3126 Surgery anesthesiology intensive care radiologySurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Anesthesiology and Pain MedicineEmerging Infectious DiseasesGood Health and Well BeingMortalidadCohort Studiebusiness
researchProduct

Surgical treatment of posterior fossa tumors in infancy and childhood: techniques and results

1993

In a collective of 72 children with tumors of the posterior fossa, the preoperative diagnosis, operation planning and performance, and use of additional procedures, like the preliminary ventricular drainage and interventriculostomy are described. The extent of intra- and postoperative complications is given. Postoperative lethality was 0% in the group operated on between 1979 and 1991. The responsible factors are discussed. The findings support the opinion of ALBRIGHT (1989) that the prognosis for such patients is most promising in the hands of a specialist in pediatric neurosurgery.

MaleVentriculostomyEpendymomamedicine.medical_specialtyAdolescentmedicine.medical_treatmentNeurosurgeryPosterior fossaPostoperative ComplicationsHumansMedicineChildIntraoperative ComplicationsMedulloblastomaBrain Neoplasmsbusiness.industryInfantAstrocytomaGeneral MedicinePrognosismedicine.diseaseSurgeryTreatment OutcomeCranial Fossa PosteriorEl NiñoChild PreschoolFemaleSurgeryNeurology (clinical)NeurosurgerybusinessComplicationNeuro Surgical Review
researchProduct

Is Dexamethasone superior to Ketorolac in reducing pain, swelling and trismus following mandibular third molar removal? A split mouth triple-blind ra…

2021

Background The preemptive use of anti-inflammatory drugs, such as corticosteroids and NSAIDs, has the potential to reduce pain, swelling and trismus following oral surgery. The aim of this study was to compare the efficacy of dexamethasone and ketorolac tromethamine in reducing pain, swelling and trismus after mandibular third molar removal. Material and Methods The researches implemented a triple-blind, randomized clinical trial. The study was conducted with ASA I individuals aging between 18 and 35 years, which were randomized and submitted to two interventions, one with 8mg dexamethasone and the other with 20mg ketorolac tromethamine given 1h before the procedure. The primary predictor v…

MaleVisual analogue scaleAnalgesicTrismusKetorolac TromethamineDexamethasonelaw.inventionRandomized controlled trialDouble-Blind MethodlawmedicineEdemaHumansGeneral DentistryDexamethasoneUNESCO:CIENCIAS MÉDICASAnti-inflammatory agentsintermaxillary fixationPain Postoperativeaccuracybusiness.industryorthognathic surgeryResearchTooth ImpactedKetorolacThird Molarintermediate splintOtorhinolaryngologyAnesthesiaTooth ExtractionSurgeryFemaleMolar ThirdTrismusSwellingmedicine.symptombone screwOral SurgerybusinessKetorolacmedicine.drugMedicina oral, patologia oral y cirugia bucal
researchProduct

Antithrombotic Therapy in Patients with Atrial Fibrillation and Acute Coronary Syndrome Treated Medically or with Percutaneous Coronary Intervention …

2019

Background: The safety and efficacy of antithrombotic regimens may differ between patients with atrial fibrillation who have acute coronary syndromes (ACS), treated medically or with percutaneous coronary intervention (PCI), and those undergoing elective PCI. Methods: Using a 2×2 factorial design, we compared apixaban with vitamin K antagonists and aspirin with placebo in patients with atrial fibrillation who had ACS or were undergoing PCI and were receiving a P2Y 12 inhibitor. We explored bleeding, death and hospitalization, as well as death and ischemic events, by antithrombotic strategy in 3 prespecified subgroups: patients with ACS treated medically, patients with ACS treated with PCI,…

MaleVitamin Kmedicine.medical_treatment030204 cardiovascular system & hematology0302 clinical medicineAntithromboticAtrial Fibrillation//purl.org/pe-repo/ocde/ford#3.02.04 [https]030212 general & internal medicineProspective Studies610 Medicine & healthAspirinVKADisease ManagementAtrial fibrillationVitamin K antagonistMiddle AgedCombined Modality TherapyHospitalizationTreatment Outcomesurgical procedures operativeElective Surgical ProceduresCardiologyApixabanDrug Therapy CombinationFemaleCardiology and Cardiovascular Medicinemedicine.drugmedicine.medical_specialtyAcute coronary syndromemedicine.drug_classPyridonesDOACHemorrhageP2Y12 inhibitor03 medical and health sciencesPercutaneous Coronary InterventionFibrinolytic AgentsPhysiology (medical)Internal medicinemedicineHumanscardiovascular diseasesAcute Coronary SyndromeAgedProportional Hazards ModelsAspirinbusiness.industryPercutaneous coronary interventionAnticoagulantsCardiovascular Agentsmedicine.diseaseConventional PCIPurinergic P2Y Receptor AntagonistsPyrazolesbusinessPlatelet Aggregation Inhibitors
researchProduct

Ischemic stroke: etiologic work-up with multidetector CT of heart and extra- and intracranial arteries

2010

[DOI:\hrefhttps://dx.doi.org/10.1148/radiol.1010080410.1148/radiol.10100804] [PubMed:\hrefhttps://www.ncbi.nlm.nih.gov/pubmed/2106292521062925]; To assess the potential of a single-session multidetector computed tomography (CT) protocol, as compared with established methods, for the etiologic work-up of acute ischemic stroke.\ Patients found to have recently experienced an ischemic stroke were recruited for this prospective study after institutional review board approval was obtained. Each patient was scheduled for two evaluation strategies: (a) a standard approach involving transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE), duplex ultrasonography (US) of the n…

Male[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/ImagingContrast MediaPilot Projects030204 cardiovascular system & hematologyBrain IschemiaBrain ischemiaElectrocardiography0302 clinical medicineRisk FactorsProspective StudiesStrokeAged 80 and overUltrasonography Doppler DuplexCerebral infarctionMiddle AgedMagnetic Resonance ImagingWork-upPlaque Atherosclerotic3. Good healthStrokesurgical procedures operativemedicine.anatomical_structureEchocardiographyCerebrovascular CirculationCirculatory systemcardiovascular systemFemaleRadiologyArteryAdultmedicine.medical_specialtySensitivity and SpecificityStatistics NonparametricCentral nervous system disease03 medical and health sciencesmedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesAgedVascular diseasebusiness.industryCoronary ThrombosisCerebral Arteriesmedicine.diseaseIopamidol[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/ImagingbusinessTomography X-Ray Computed030217 neurology & neurosurgery
researchProduct

Perioperative risk of bleeding with antithrombotic agents in macular surgery: a national, prospective, multicentre study

2020

International audience; Purpose To compare the risk of haemorrhagic complications in elective macular surgery between patients with no antithrombotic (AT) treatment (defined as patients with no history of AT therapy or who discontinued AT therapy) and patients who continued AT treatment during the surgery. Methods E-case report forms were prospectively recorded in a database before vitreoretinal surgery and 1 month after. Data on patient characteristics, surgical techniques, haemorrhagic complications and antithrombotic status were collected. Patients with retinal detachment, proliferative diabetic retinopathy and previous retinal haemorrhage were excluded. Results A total of 748 procedures…

Male[SDV]Life Sciences [q-bio]030204 cardiovascular system & hematologynoncardiac surgeryantiplateletsurgery0302 clinical medicineRisk FactorsAntithromboticMedicineProspective Studiesoral anticoagulantsguidelinesantithrombotic agenteducation.field_of_studyAnticoagulantvitreoretinalRetinal HemorrhageGeneral MedicineDiabetic retinopathy3. Good healthPopulation SurveillanceFemalemacular surgeryhaemorrhagehemorrhagemanagementmedicine.medical_specialtymedicine.drug_classPopulationPostoperative Hemorrhagemaintenance03 medical and health sciencesHumans[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrganseducationAgedbusiness.industryanticoagulantAnticoagulantsPerioperativeOdds ratioRetinal Perforationsmedicine.diseasedual antiplatelet therapyvitreoretinal surgeryConfidence intervalSurgerywarfarinOphthalmology030221 ophthalmology & optometrybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up StudiesRetinal haemorrhage
researchProduct

Evidence for unintentional emotional contagion beyond dyads.

2013

International audience; Little is known about the spread of emotions beyond dyads. Yet, it is of importance for explaining the emergence of crowd behaviors. Here, we experimentally addressed whether emotional homogeneity within a crowd might result from a cascade of local emotional transmissions where the perception of another's emotional expression produces, in the observer's face and body, sufficient information to allow for the transmission of the emotion to a third party. We reproduced a minimal element of a crowd situation and recorded the facial electromyographic activity and the skin conductance response of an individual C observing the face of an individual B watching an individual …

Male[SDV]Life Sciences [q-bio]HappinessEmotionsFacial MusclesPoison controllcsh:Medicine050109 social psychologyEmotional contagionSocial and Behavioral SciencesEmotional competence[SCCO]Cognitive scienceCognitionPsychologyEmotional expressionCooperative Behaviorlcsh:Sciencemedia_commonMultidisciplinarySocial perception05 social sciencesExperimental PsychologyFearFacial ExpressionSocial PerceptionFemale[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]CuesPsychologyResearch ArticleCognitive psychologyAdultAdolescentSocial PsychologyCognitive Neurosciencemedia_common.quotation_subjectPsychological Anthropology050105 experimental psychologyYoung AdultMotor ReactionsPerceptionHumans0501 psychology and cognitive sciences[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]BiologyBehaviorFacial expression[ SDV ] Life Sciences [q-bio]lcsh:RCognitive PsychologyNeurosciences[SCCO] Cognitive scienceAnthropologyNeurons and CognitionHappinesslcsh:QMass BehaviorPhotic StimulationNeuroscience
researchProduct