Search results for "Ophthalmology"

Neural interaction of retinal aftereffects and contrast adaptation in perception of gabor gratings

2010

Cataract surgery in West Africa: is couching still a choice?

2012

Model Eye Incorporating a Manually Tunable Polymer Lens and Microfluidics Chamber for Simulation of Vitreous Floaters

2016

a model eye incorporating a manually tunable lens and microfluidics chamber for simulation of vitreous floaters has been described. Aberrations correspond to average values in population and diffraction effects could be observed.

Polyunsaturated fatty acids and Plasmalogens in diabetics

2012

Purpose Plasmalogens (PLS) are phospholipids characterized by a vinyl ether bond and a preferential esterification of polyunsaturated fatty acids (PUFA). We have previously shown that the lack of PLS leads to retinal hyper-capillarization. We hypothesize that PLS are negative regulators of vascular development, and aimed to check their circulating levels in diabetic patients. Methods Blood samples were collected from 88 patients and 14 control subjects. Among diabetics we had 14 patients without diabetic retinopathy (DR), 12 with a mild non proliferative DR, 12 with a moderate non proliferative DR, 22 with a severe non proliferative DR and 24 with a proliferative DR (PDR). Erythrocytes were…

Lipid and fatty acid profile of the retina, RPE/choroid and lacrimal gland, and associations with dietary fatty acids in human subjects

2008

Purpose The contribution of dietary lipids to the accumulation of lipids in the retina during ageing and in the course of age related maculopathies remains under debate. Our objective was to establish associations between fatty acid profiles of ocular structures, and adipose tissue as a surrogate for the past dietary intake of the subjects. Methods Lipids and fatty acids were analyzed by tandem thin-layer chromatography-flame ionization detection and gas chromatography-flame ionization detection from the neural retina, RPE/choroid, lacrimal gland and adipose tissue, collected from 19 women and 8 men, aged 59–95 years. Results DHA concentrations in the neural retina were positively associate…

Effect of the color of the intraocular lens on optical and visual quality

2014

Purpose: To analyze the optical quality of intraocular lenses (IOL) with an orange (PC440Y) and a yellow (SN60AT) filter, and correlate these results with the visual quality of patients with these implants. Setting: Fisabio Oftalmología Médica, Valencia, Spain. Design: Randomized prospective study. Materials and Methods: The IOL optical quality was determined using the modulation transfer function (MTF) and the spectral transmission. The visual quality of 87 eyes with cataract (51 with orange filter and 36 with yellow filter) was determined by best corrected visual acuity (BCVA) and contrast sensitivity function (CSF) under photopic and mesopic conditions. To analyze the results, we use a S…

All-trans to 11-cis retinol isomerization in nuclear membrane fraction from bovine retinal pigment epithelium

1991

Abstract Isomerization of all-trans to 11-cis retinol has been studied in a membrane preparation from the nuclear fraction of bovine retinal pigment epithelium. When the nuclear membrane preparation deprived of endogenous retinoids is incubated with 4·5 μ m all-trans-retinol, the mean value calculated for the isomerase activity is 1·32 nmol 11-cis retinol formed hr−1 mg protein−1. Simultaneous formation of all-trans and 11-cis retinyl esters is also observed in the nuclear preparation. When assayed under the same experimental condition, RPE 150 000 g post-nuclear sediment shows about 70% of the isomerase activity found in the nuclear membrane fraction. Treatment of the nuclear membrane frac…

Questions for The Psychology of the Artful Mind

2019

This paper reconstructs the &ldquo

Systemic therapies for mucopolysaccharidosis: ocular changes following haematopoietic stem cell transplantation or enzyme replacement therapy - a rev…

2010

The management of mucopolysaccharidosis (MPS) is focused on the multi-organ, sometimes life-threatening, clinical manifestations that occur over time. In the past, the limited, symptom-based treatment options led physicians to adopt a palliative approach towards individual disease-associated complications. The availability of systemic treatments such as haematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT) has created a better prognosis for MPS patients, particularly when initiated early in life. As part of an integrated management approach, these therapies could be valuable in managing the ocular features that are present in many children with MPS. HSCT has b…

Visual Acuity and Contrast Sensitivity Depending from Keratoconus Apex Position

2017

Abstract Various studies have demonstrated that patients with keratoconus have significant loss of contrast sensitivity while its value varies in different studies. None of these studies has analysed reduced contrast sensitivity depending on the position of apex of corneal conus. Visual acuity and contrast sensitivity were evaluated for patients with keratoconus using the FrACT software. Contrast sensitivity was assessed at the following frequencies: 1, 3, 5, 7, 9, 11, 13, and 15 cycles per degree (cpd). Twenty-four eyes with keratoconus were analysed. Contrast sensitivity was significantly lower for patients with the apex at the centre compared with apex on the periphery both with (p = 0.0…