Search results for "Ophthalmology"

showing 10 items of 1738 documents

Secondary Vitrectomy with Internal Limiting Membrane Plug due to Persistent Full-Thickness Macular Hole OCT-Angiography and Microperimetry Features: …

2020

Purpose. To study the features in OCT-angiography and microperimetry in eyes with persistent full-thickness macular hole (FTMH) closed with the secondary plana vitrectomy (PPV) with autologous internal limiting membrane (ILM) plug. Methods. Secondary PPV was performed with closing the persistent FTMH with ILM plug, C3F8 tamponade, and face-down positioning. Four patients were followed for 6 months with best corrected visual acuity (BCVA) measurement, SD-OCT and OCT-A, and microperimetry. The results were compared with the fellow eye; in two patients, it was the healthy eye, and in two remaining eyes, successfully closed FTMH after primary PPV. Results. ILM flap was integrated in all cases w…

medicine.medical_specialtygenetic structuresArticle Subjectmedicine.medical_treatmentVitrectomyOCT macular hole03 medical and health scienceschemistry.chemical_compound0302 clinical medicineFovealOphthalmologymedicineFull-thickness macular holeMacular holebusiness.industryInternal limiting membraneRetinalRE1-994medicine.diseaseeye diseasesOphthalmologychemistryClinical Study030221 ophthalmology & optometryTamponadesense organsbusinessMicroperimetry030217 neurology & neurosurgery
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Evolving European guidance on the medical management of neovascular age related macular degeneration

2006

BACKGROUND: Until recently, only two options were available for the treatment of choroidal neovascularisation (CNV) associated with age related macular degeneration (AMD)-thermal laser photocoagulation and photodynamic therapy with verteporfin (PDT-V). However, new treatments for CNV are in development, and data from phase III clinical trials of some of these pharmacological interventions are now available. In light of these new data, expert guidance is required to enable retina specialists with expertise in the management of AMD to select and use the most appropriate therapies for the treatment of neovascular AMD. METHODS: Consensus from a round table of European retina specialists was obt…

medicine.medical_specialtygenetic structuresBevacizumabAntibodies Monoclonal HumanizedTriamcinolone AcetonideMacular DegenerationCellular and Molecular NeuroscienceRanibizumabOphthalmologymedicineHumansPregnadienediolsEvidence-Based Medicinemedicine.diagnostic_testbusiness.industryAntibodies MonoclonalAptamers NucleotideMacular degenerationFluorescein angiographymedicine.diseaseVerteporfinChoroidal Neovascularizationeye diseasesSensory SystemsOphthalmologyTreatment Outcomemedicine.anatomical_structureChoroidal neovascularizationPhotochemotherapyPerspectivesense organsAnecortave acetateChoroidRanibizumabmedicine.symptombusinessmedicine.drugBritish Journal of Ophthalmology
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Postoperative Lens Position Preoperatively Determined by Scheimpflug Photography

1999

The position of the artificial lens has an important influence on refractive power calculation. We compared the position of the crystalline lens with that of the artificial lens after cataract surgery by means of Scheimpflug photography. A difference in position of approximately 0.8 mm in the anterior direction could be determined.

medicine.medical_specialtygenetic structuresComputer Science::Neural and Evolutionary ComputationScheimpflug principlePhysics::OpticsAfter cataractOptical powerCataract ExtractionAstrophysics::Cosmology and Extragalactic Astrophysicslaw.inventionCataract extractionCellular and Molecular NeuroscienceLens Implantation IntraocularPosition (vector)lawProsthesis FittingOphthalmologyLens CrystallinePreoperative Caremental disordersPhotographymedicineHumansPostoperative PeriodLenses Intraocularbusiness.industryPhotographyGeneral Medicineeye diseasesSensory SystemsLens (optics)OphthalmologyOptometrysense organsbusinesspsychological phenomena and processesOphthalmic Research
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Komplikationen nach Molteno-Implantat: Eine Falldarstellung

2003

We present a 43-year old patient with refractory secondary glaucoma, who showed epithelial downgrowth into the anterior chamber following Molteno implant surgery. It will be discussed, whether the Molteno implant or the following keratoplasty, which was necessary because of corneal decompensation, caused the epithelial downgrowth.

medicine.medical_specialtygenetic structuresCorneal Decompensationbusiness.industryEye diseaseGlaucomamedicine.diseaseeye diseasesSurgeryOphthalmologyRefractoryOphthalmologymedicineEpithelial downgrowthsense organsImplantComplicationbusinessMolteno implantKlinische Monatsblätter für Augenheilkunde
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Locking Y Lateral Canthopexy as a Treatment for Dry Eye Disease Caused by Eyelid Malposition

2020

PURPOSE The signs and symptoms of dry eye disease (DED) can affect the quality of life of patients. This study analyzes whether locking Y lateral canthopexy improves patients' quality of life and in what way it does so (based on the ocular surface disease index questionnaire) and DED signs (measured by the fluorescein breakup time, tear osmolarity, Schirmer test, and corneal staining) in patients with DED caused by a eyelid malposition or impaired blink dynamics. METHODS This was a case-control study. Forty eyes of 20 patients with DED and lateral canthal disinsertion examined at the University Hospital La Ribera during a 1-year period from November 2016 to November 2017. The 40 eyes were d…

medicine.medical_specialtygenetic structuresDisease03 medical and health sciences0302 clinical medicineOphthalmologyHumansMedicineOcular Surface Disease IndexIn patientSchirmer testPeriosteumbusiness.industryEyelidsGeneral MedicineTear osmolarityeye diseasesLateral canthopexyOphthalmologymedicine.anatomical_structureCase-Control StudiesTearsEyelid DiseasesQuality of Life030221 ophthalmology & optometryDry Eye SyndromesSurgeryEyelid malpositionsense organsbusinessOphthalmic Plastic & Reconstructive Surgery
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Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies

2022

Globally, 2.2 billion people live with some form of vision impairment and/or eye disease. To date, most systematic reviews examining associations have focused on a single eye disease and there is no systematic evaluation of the relationships between eye diseases and diverse physical and mental health outcomes. Moreover, the strength and reliability of the literature is unclear. We performed an umbrella review of observational studies with meta analyses for any physical and/or mental comorbidities associated with eye disease. For each association, random-effects summary effect size, heterogeneity, small-study effect, excess significance bias and 95% prediction intervals were calculated, and …

medicine.medical_specialtygenetic structuresEye diseaseDiseaseType 2 diabetesReview ArticleCataractCognitionEye diseasePregnancyRisk FactorsDiabetes mellitusInternal medicinemedicineHumansDepression (differential diagnoses)Diabetic Retinopathybusiness.industryInfant NewbornReproducibility of ResultsRetinopathy of prematurityGlaucomaDiabetic retinopathyMacular degenerationmedicine.diseaseeye diseasesOphthalmologyObservational Studies as TopicDiabetes Mellitus Type 2Femalebusiness
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Histology and Fine Structure of the Iris and Outflow System Following Latanoprost Therapy

2002

Latanoprost therapy can lead to iris darkening in susceptible individuals, particularly those with hazel eyes. Concerns have been raised about whether latanoprost, and for that matter other prostanoids, may have a harmful effect on the iris. In addition, it is unknown whether latanoprost causes increased pigmentation of the outflow pathways that might eventually lead to blockage and a type of pigmentary glaucoma. The present study summarizes findings from the authors' own laboratories on the effects of latanoprost as seen by light and electron microscopy of the iris and outflow tissues and reviews the as yet limited, relevant literature. The findings support the proposal that latanoprost-in…

medicine.medical_specialtygenetic structuresEye diseasemedicine.medical_treatmentIrisGlaucomaMelanocyteMelaninchemistry.chemical_compoundTrabecular MeshworkOphthalmologymedicineHumansTrabeculectomyIris (anatomy)LatanoprostAntihypertensive AgentsIntraocular PressureMelaninsEye Colorbusiness.industryfungiGlaucomamedicine.diseaseHyperpigmentationeye diseasesSurgeryOphthalmologymedicine.anatomical_structureIris DiseaseschemistryProstaglandins F SyntheticLatanoprostMelanocytessense organsmedicine.symptombusinessPigmentation DisordersSurvey of Ophthalmology
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Eye fluke-induced cataract formation in fish: quantitative analysis using an ophthalmological microscope

2004

We examined the parasite-induced cataract formation in rainbow trout (Oncorhynchus mykiss) using slit-lamp microscopy to determine the relationship between cataract intensity and number of Diplostomum spathaceum parasites that were established in the lens. Cataract intensity increased significantly with parasite burden, but was also affected by the pattern of exposure to the parasite cercariae. The slit-lamp methodology proved useful in scoring the cataracts since it provides a 3-dimensional view into the lens and gives an actual picture of the location and intensity of the cataracts, which allows detailed investigations of mechanisms underlying cataract formation in various fish species. P…

medicine.medical_specialtygenetic structuresFish farmingAquacultureTrematode InfectionsDiagnostic Techniques OphthalmologicalCataractFish DiseasesRandom AllocationAquacultureCataractsOphthalmologymedicineAnimalsParasite hostingEye Infections Parasiticbiologybusiness.industryAnatomybiology.organism_classificationmedicine.diseaseeye diseasesInfectious Diseasesmedicine.anatomical_structureDiplostomum spathaceumOncorhynchus mykissLens (anatomy)Animal Science and ZoologyParasitologyRainbow troutTrematodasense organsTrematodabusinessParasitology
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Clinical and genetic update of corneal dystrophies.

2019

The International Committee for Classification of Corneal Dystrophies (IC3D) distinguishes between 22 distinct forms of corneal dystrophy which are predominantly autosomal dominant, although autosomal recessive and X-chromosomal dominant patterns do exist. Before any genetic examination, there should be documentation of a detailed corneal exam of as many affected and unaffected family members as possible, because detailed phenotypic description is essential for accurate diagnosis. Corneal documentation should be performed in direct and indirect illumination at the slit lamp with the pharmacologically dilated pupil. For the majority of the corneal dystrophies, a phenotype-genotype correlatio…

medicine.medical_specialtygenetic structuresGenetic ExaminationCorneal dystrophyCollagen Type ITransforming Growth Factor beta1Cellular and Molecular NeuroscienceCorneaOphthalmologyGenotypemedicineHumansGenetic Predisposition to DiseaseCorneal Dystrophies Hereditarybusiness.industryEpithelium Cornealmedicine.diseasePhenotypeeye diseasesSensory SystemsCollagen Type I alpha 1 ChainOphthalmologyEpithelial recurrent erosion dystrophymedicine.anatomical_structuresense organsDifferential diagnosisbusinessTGFBIExperimental eye research
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Optical quality of the diabetic eye: a review

2014

Diabetes mellitus is a metabolic disorder characterized by the presence of chronic hyperglycaemia. Several structural, morphological, and physiological changes in each of ocular component have been described in detail during the past decades. Due to these abnormalities, the diabetic patient undergoes a degradation of the retinal image by an increase of higher ocular aberrations and ocular scattering coming from mainly tear film, cornea, and crystalline lens. This review aims to provide an overview of current knowledge about the effects of diabetes mellitus in these optical phenomena and its consequence on the visual quality of the diabetic patient.

medicine.medical_specialtygenetic structuresGlaucomaReviewRetinaOphthalmic pathologyNeuro-ophthalmologyCorneaCorneaOphthalmologyDiabetes mellitusLens CrystallinemedicineDiabetes MellitusHumansRetinabusiness.industryMetabolic disordermedicine.diseaseRefractive Errorseye diseasesVitreous BodyOphthalmologymedicine.anatomical_structureLens (anatomy)Optometrysense organsbusiness
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