Search results for "Ophthalmology"
showing 10 items of 1738 documents
Optical coherence tomography-based retinal vessel analysis for the evaluation of hypertensive vasculopathy
2013
Purpose Evaluation of retinal vessels in cardiovascular disease traditionally relies upon funduscopy, but more recently digital photo analysis has expanded the spectrum. As spectral domain optical coherence tomography (OCT) allows an in-vivo assessment of retinal tissue and its vessels on a histological scale, our study aimed at using this tool for the analysis of the retinal vasculature. Methods Circumferential peripapillary OCT scans (3DOCT-2000; Topcon Inc., Tokyo, Japan), with centration on the optic nerve head, were taken from 20 eyes (20 participants) with normal blood pressure and 20 eyes (20 participants) with arterial hypertension above 120 mmHg (mean blood pressure). The diameter …
Real-time control for transscleral cyclophotocoagulation.
1998
• Background: In transscleral cyclophotocoagulation, the surgeon cannot directly observe the applied laser effects. Overdosage, possibly resulting in unwanted pop effects, or underdosage with no therapeutic effect therefore often occur. • Method and materials: Laser radiation passing through the sclera and ciliary body is partly reflected from the fundus and can be monitored from outside the eye by a detector system. Since all other parameters influencing the intensity of the recorded radiation are constant in time during one laser exposure, the time dependence of this radiation directly reflects the change of transmission of the treated tissue. The laser exposure therefore can be stopped b…
Subclinical optic neuropathy in Fabry disease.
2009
Fabry disease is a rare X-linked lysosomal storage disorder, caused by the deficiency of alpha-galactosidase A. Ophthalmic features comprise a cornea verticillata, conjunctival aneurysms, tortuous conjunctival and/or retinal vessels, and anterior and posterior subcapsular cataracts. The issue of a possible subclinical optic neuropathy in Fabry disease has been raised recently. In this pilot study, we looked for signs of optic neuropathy in our cohort of Fabry patients.Thirty-one Fabry patients (15 male, 16 female, mean age 34 years) underwent an ophthalmological investigation consisting of assessment of best corrected visual acuity, slit lamp investigation, testing of pupillary reaction, fu…
Effect of 3rd-order aberrations on human vision
2007
To investigate the effect of 3rd-order aberrations on human vision.Grupo de Ciencias de la Visión, University of Murcia, Murcia, Spain.The 3rd-order aberrations coma and trefoil were induced with purpose-designed soft contact lenses, 3 inducing coma (low [0.05 microm], medium [0.13 microm], high [1.03 microm]) and 3 inducing trefoil (low [0.07 microm], medium [0.17 microm], high [0.96 microm]). Monocular high-contrast (HCVA) and low-contrast (LCVA) visual acuities and contrast sensitivity were measured in 11 subjects wearing contact lenses with a 5.0 mm artificial pupil.The reduction in HCVA and LCVA was statistically significant only for the highest coma and trefoil values (P.0001). For co…
Long-term follow-up of a multifocal apodized diffractive intraocular lens after cataract surgery.
2007
Purpose To report the long-term performance of the AcrySof ReSTOR SA60D3 intraocular lens (IOL) after cataract surgery. Setting University Hospital Maastricht, Maastricht, The Netherlands. Methods This prospective clinical trial comprised 44 eyes (22 consecutive patients) having cataract surgery with implantation of the ReSTOR IOL. Monocular and binocular uncorrected distance visual acuity, best corrected distance visual acuity, uncorrected near visual acuity, best distance-corrected near visual acuity, spectacle dependence, undesired visual symptoms, patient satisfaction, and incidence of posterior capsule opacification were analyzed 6 months and 3 years postoperatively. Results The mean u…
Myxoma of the orbit: a clinicopathologic report.
1990
A 27-year-old white man developed proptosis of his left eye over a period of 2 years. It was associated with vertical diplopia and displacement of the left globe down and laterally. Ultrasonography showed a cystic mass in the superior orbital region. Computed tomography (CT) demonstrated a solid, well-defined lesion behind the globe displacing the optic nerve medially. A transfrontal craniotomy revealed a nodular mass in the posterior and superior orbit, which extended anteriorly up to the globe. Histopathology, immunohistochemistry, and transmission electron microscopy proved the tumor to be a myxoma.
Change in pupil size after implantation of an iris-fixated toric phakic intraocular lens
2005
Purpose To evaluate the changes in pupil size after implantation of an iris-supported toric phakic intraocular lens (TPIOL) for correction of myopia and hyperopia with astigmatism. Setting Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany. Methods Twenty-two myopic eyes and 9 hyperopic eyes were included in the study. The mean age of the 2 groups was 34 years and 40 years, respectively. The scotopic pupil size was measured with a handheld infrared pupillometer (Colvard, Oasis Medical) before and 6 months after implantation of the TPIOL. All examinations were performed under scotopic conditions after 2 minutes of dark adaptation with the fellow eye covered. Intraindi…
Evaluating tear clearance rate with optical coherence tomography
2017
Purpose: To assess the early-phase of tear clearance rate (TCR) with anterior segment optical coherence tomography (OCT) and to determine the association between TCR and other clinical measures of the tear film in a group of young subjects with different levels of tear film quality. Methods: TCR was classified as the percentage decrease of the inferior tear meniscus height 30s after instillation of 5uL 0.9% saline solution. Fifty subjects (32F and 18M) aged (mean +/- standard deviation) 25.5 +/- 4.3 years volunteered for the study. It consisted of a review of medical history, Ocular Surface Disease Index (OSDI) questionnaire, tear film osmolarity measurements, slit lamp examination and TCR …
Effect of trypan blue on the elasticity of the human anterior lens capsule.
2007
Purpose To evaluate the effect of trypan blue (VisionBlue) staining on the elastic properties of the human anterior lens capsule. Setting Center for Vision Science, Ruhr University Eye Hospital, Bochum, Germany. Methods Nineteen anterior capsules were obtained from 19 human eyes at the time of cataract operation. Two same-size strips were prepared from each capsule; 1 was exposed to trypan blue staining for 10 seconds, and the other was a control. The elasticity measurements were performed on both specimens using a modified rheometer. Results The mean age of the patients was 75.3 years ± 13.3 (SD) (range 35 to 89 years). Sixty-three measurements of 19 suitable specimen pairs were performed.…
Outcome of orbital decompression for disfiguring proptosis in patients with Graves' orbitopathy using various surgical procedures
2009
Aim: To compare the outcome of various surgical approaches of orbital decompression in patients with Graves' orbitopathy (GO) receiving surgery for disfiguring proptosis.Method: Data forms and questionnaires from consecutive, euthyroid patients with inactive GO who had undergone orbital decompression for disfiguring proptosis in 11 European centres were analysed.Results: Eighteen different (combinations of) approaches were used, the swinging eyelid approach being the most popular followed by the coronal and transconjunctival approaches. The average proptosis reduction for all decompressions was 5.0 (SD 2.1) mm. After three-wall decompression the proptosis reduction was significantly greater…