Search results for "Ophthalmoscopy"

showing 4 items of 34 documents

A/V ratio as predicted by full width at half maximum and by blood vessel tracking in presence of ocular aberrations

2011

Aberrations impact A/V ratio calculated from full width at half maximum. We investigated whether aberrations affect A/V ratio calculated by tracking the vessels. Aberrations changed the A/V ratio. We conclude that aberrations impact A/V ratio.

PhysicsFull width at half maximummedicine.anatomical_structureOpticsIntraocular lensesbusiness.industrymedicineTracking (particle physics)businessAdaptive opticsBlood vesselScanning laser ophthalmoscopy
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BBS1 Mutations in a Wide Spectrum of Phenotypes Ranging From Nonsyndromic Retinitis Pigmentosa to Bardet-Biedl Syndrome

2012

OBJECTIVE: To investigate the involvement of the Bardet-Biedl syndrome (BBS) gene BBS1 p.M390R variant in nonsyndromic autosomal recessive retinitis pigmentosa (RP). METHODS: Homozygosity mapping of a patient with isolated RP was followed by BBS1 sequence analysis. We performed restriction fragment length polymorphism analysis of the p.M390R allele in 2007 patients with isolated RP or autosomal recessive RP and in 1824 ethnically matched controls. Patients with 2 BBS1 variants underwent extensive clinical and ophthalmologic assessment. RESULTS: In an RP proband who did not fulfill the clinical criteria for BBS, we identified a large homozygous region encompassing the BBS1 gene, which carrie…

ProbandMaleBBS1Genetics and epigenetic pathways of disease [NCMLS 6]DNA Mutational AnalysisEvaluation of complex medical interventions Genomic disorders and inherited multi-system disorders [NCEBP 2]GenotypeEthnicityPrevalenceIsraelGeneticseducation.field_of_studyRetinitis Pigmentosa/diagnosisMiddle AgedDisease gene identificationPedigreeEuropePhenotypeFemaleMicrotubule-Associated ProteinsRetinitis PigmentosaAdultcongenital hereditary and neonatal diseases and abnormalitiesCanadaPopulationCanada/epidemiologyMicroscopy AcousticMutation MissenseEthnic GroupsDNA/geneticsBiologyEurope/epidemiologyGenomic disorders and inherited multi-system disorders [IGMD 3]Bardet-Biedl Syndrome/diagnosisBardet–Biedl syndromeRetinitis pigmentosamedicineElectroretinographyHumansAlleleeducationBardet-Biedl SyndromeIsrael/epidemiologyAllelesDNAMicrotubule-Associated Proteins/geneticsmedicine.diseaseOphthalmoscopyOphthalmologyGenetics and epigenetic pathways of disease Genomic disorders and inherited multi-system disorders [NCMLS 6]
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OPTICAL COHERENCE TOMOGRAPHIC FINDINGS IN BIETTI’S CRYSTALLINE TAPETORETINAL DYSTROPHY

2014

Purpose: To report the optical coherence tomography (OCT) findings of Bietti crystalline tapetoretinal dystrophy. Design: Observational case report. Methods: A subject with Bietti crystalline tapetoretinal dystrophy was evaluated with ophthalmoscopy, fluorescein angiography, and OCT (Stratus). Results: OCT showed thinning and hyporeflectivity of the outer nuclear layer in the macula due to photoreceptor degeneration. The retinal areas showing atrophy of the retinal pigment epithelium displayed greater penetration of the optical beam into the choroid and visualization of residual choroidal vessels. The hyperreflective band normally seen under the neurosensory retina was extremely wide when a…

Retinamedicine.medical_specialtyRetinal pigment epitheliumgenetic structuresmedicine.diagnostic_testbusiness.industryRetinalGeneral MedicineFluorescein angiographyeye diseasesOphthalmoscopyOphthalmologychemistry.chemical_compoundmedicine.anatomical_structureOptical coherence tomographychemistryOphthalmologymedicinesense organsChoroidbusinessOuter nuclear layerRETINAL Cases & Brief Reports
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Retinal vasculature segmentation and measurement framework for color fundus and SLO images

2020

Abstract The change in vascular geometry is an indicator of various health issues linked with vision and cardiovascular risk factors. Early detection and diagnosis of these changes can help patients to select an appropriate treatment option when the disease is in its primary phase. Automatic segmentation and quantification of these vessels would decrease the cost and eliminate inconsistency related to manual grading. However, automatic detection of the vessels is challenging in the presence of retinal pathologies and non-uniform illumination, two common occurrences in clinical settings. This paper presents a novel framework to address the issue of retinal blood vessel detection and width me…

business.industryComputer scienceBiomedical EngineeringRetinalVascular geometryFundus (eye)Scanning laser ophthalmoscopychemistry.chemical_compoundchemistryIterative thresholdingAutomatic segmentationGraph (abstract data type)SegmentationComputer visionArtificial intelligencebusinessBiocybernetics and Biomedical Engineering
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