Search results for "Opus"

An analysis of the stability of rural tourism as a desired condition for sustainable tourism

2019

Abstract Tourism is a key sector in the sustainable development of rural environments. Its ability to create stable employment and an acceptable level of profits is conditioned by the stability of tourist activity throughout the year. This paper compares the level of seasonality of a group of rural destinations to that of coastal and urban destinations. By doing so, we intend to determine whether seasonality-related problems exist in the rural environment or not. The second aim is related to the first one: the proposal of a new, more comprehensive and objective methodology that can measure the intensity of seasonality based on a DP2 synthetic indicator. The DP2 indicator groups information …

Dynamics of the termination of global alliances: probing the past, analyzing the present and defining the frontiers for future research

2022

PurposeWhile the number of global alliance terminations in the business world has grown steadily during the past few decades, the scholarly literature on strategic alliance (SA) termination remains limited. This research paper aims to perform a bibliometric analysis of the literature on alliance termination and propose a model for future research agenda that links the termination phase to the pre-alliance termination phase and post alliance termination phase.Design/methodology/approachA search query on global alliance termination identified a total of 69 research papers from the Scopus database, and a bibliometric analysis was performed using the bibliometrix R-package and VOSviewer. The an…

Are Traffic Announcements Really Effective? A Systematic Review of Evaluations of Crash-Prevention Communication Campaigns

2021

Communication campaigns are commonly used in the traffic and road safety sector to raise public awareness of the importance of avoiding risky road user attitudes and behaviors. Surprisingly few of these communication campaigns evaluate their effectiveness in a formal and comprehensive manner. The core aim of the present systematic review is to identify the type of studies that evaluate the effectiveness of campaigns in this sector, in order to identify and contrast their main findings. This systematic review followed the PRISMA methodology, by means of which the relevant articles based on the search term were identified. A total of 613 indexed articles were filtered, and a final set of 27 a…

Seasonal trend of Anisakidae infestation in South Mediterranean bluefish

2020

A total of 1104 fish samples from markets of Sicily were analysed for the detection and species identification of Anisakidae nematodes. The preliminary analysis of the fish samples showed the presence of 2459 larvae. All the fish species revealed different prevalence of infestation, with a maximum of 100% for Lepidopus caudatus and a minimum of 4.5% in Sardina pilchardus. The 80% of the larvae examined by PCR-RFLP analysis belonged to Anisakis pegreffii species. The seasonal infestation trend of Anisakis was evaluated in all the fish sample examined. The results of the seasonal infestation trend showed a marked connection with the ecological aspects of the fish species examined. As far as w…

Challenges and barriers in mental healthcare systems and their impact on the family: A systematic integrative review

2020

The aim of this systematic integrative review is to analyse the challenges and barriers found in mental healthcare systems and the impact they have on the family. Searches were made of the Web of Science, Scopus, Medline and Cochrane databases using terms relating to mental health, family care and healthcare systems. We included and critically evaluated studies published in English between 2015 and 2019 that directly or indirectly analysed public mental health policies and the consequences they have for the family. We analysed our findings following the inductive content analysis approach. A total of 32 articles that met quality indicators were identified. Very closely related structural, c…

Villification: How the Gut Gets Its Villi

2013

Intestinal Villus Formation The intestinal villi are essential elaborations of the lining of the gut that increase the epithelial surface area for nutrient absorption. Shyer et al. (p. 212 , published online 29 August; see the Perspective by Simons ) show that in both the developing human and chick gut, the villi are formed in a step-wise progression, involving the sequential folding of the endoderm into longitudinal ridges, via a zigzag pattern, to finally form individual villi. These changes are established through the differentiation of the smooth muscle layers of the gut, restricting the expansion of the adjacent proliferating and growing endoderm and mesenchyme, generating compressive …

CONSERVED CELLULAR AND MOLECULAR MECHANISMS IN DEVELOPMENT

2002

This review discusses examples of conserved cellular and molecular mechansims in development, including the pathway of signal transduction between the photoreceptors R8 and R7 in Drosophila, which is compared to vulval induction in Caenorhabditis elegans. The Wg pathway in Drosophila is compared, first, to the Wnt pathway in dorsal mesoderm specification in Xenopus: second, to the same pathway in sea urchins; third, to the equivalent in the mom cascade of C. elegans; and finally, to parts of the equivalent pathway in Dictyostelium discoideum. The conserved expression of some hox genes in vertebrate limb buds and in the heads or tails of several invertebrate and vertebrate embryos is also il…

Applying Support Vector Machines for Gene Ontology based gene function prediction.

2004

Abstract Background The current progress in sequencing projects calls for rapid, reliable and accurate function assignments of gene products. A variety of methods has been designed to annotate sequences on a large scale. However, these methods can either only be applied for specific subsets, or their results are not formalised, or they do not provide precise confidence estimates for their predictions. Results We have developed a large-scale annotation system that tackles all of these shortcomings. In our approach, annotation was provided through Gene Ontology terms by applying multiple Support Vector Machines (SVM) for the classification of correct and false predictions. The general perform…

Immunodeficiency Syndromes

2010

Social determinants of therapy failure and multi drug resistance among people with tuberculosis: A review

2017

Background Social determinants influence health and the development of tuberculosis (TB). However, a paucity of data is available considering the relationship of social determinants influencing therapy failure and multi drug resistance (MDR). We conducted a review investigating the relationship of common social determinants on therapy failure and MDR in people with TB. Methods PubMed and SCOPUS were searched without language restrictions until February 02, 2016 for studies reporting the association between socioeconomic factors (income, education and alcohol abuse) and therapy failure or MDR-TB. The association between social determinants and outcomes was explored by pooling data with a ran…