Search results for "Orexin"
showing 10 items of 82 documents
Recent results from Borexino
2016
Journal of Physics Conference Series. - 798, International Conference on Particle Physics and Astrophysics : 10-14 October 2016, Moscow, Russian Federation / proceedings editors: 1. issue: cosmic rays: Arkady Galper (MEPhI, Moscow, Russia) [und 7 andere] 2nd International Conference on Particle Physics and Astrophysics, ICPPA 2016, Moscow, Russia, 11 Oct 2016 - 14 Oct 2016; Bristol : IOP Publ., Journal of Physics Conference Series, 798, 012114 pp. (2017). doi:10.1088/1742-6596/798/1/012114
The $^{144}$Ce source for SOX
2015
International audience; The SOX (Short distance neutrino Oscillations with BoreXino) project aims at testing the light sterile neutrino hypothesis. To do so, two artificials sources of antineutrinos and neutrinos respectively will be consecutively deployed at the Laboratori Nazionali del Gran Sasso (LNGS) in close vicinity to Borexino, a large liquid scintillator detector. This document reports on the source production and transportation. The source should exhibit a long lifetime and a high decay energy, a requirement fullfilled by the (144)Ce-(144)Pr pair at secular equilibrium. It will be produced at FSUE “Mayak” PA using spent nuclear fuel. It will then be shielded and packed according t…
Solar neutrino detectors as sterile neutrino hunters
2016
International audience; The large size and the very low radioactive background of solar neutrino detectors such as Borexino at the Gran Sasso Laboratory in Italy offer a unique opportunity to probe the existence of neutrino oscillations into new sterile components by means of carefully designed and well calibrated anti-neutrino and neutrino artificial sources. In this paper we briefly summarise the key elements of the SOX experiment, a program for the search of sterile neutrinos (and other short distance effects) by means of a (144)Ce-(144)Pr anti-neutrino source and, possibly in the medium term future, with a (51)Cr neutrino source.
Overview and accomplishments of the Borexino experiment
2015
International audience; The Borexino experiment is running at the Laboratori del Gran Sasso in Italy since 2007. Its technical distinctive feature is the unprecedented ultralow background of the inner scintillating core, which is the basis of the outstanding achievements accumulated by the experiment. In this talk, after recalling the main features of the detector, the impressive solar data gathered so far by the experiment will be summarized, with special emphasis to the most recent and prominent result concerning the detection of the fundamental pp solar neutrino flux, which is the direct probe of the engine mechanism powering our star. Such a milestone measurement puts Borexino in the un…
Immunohistochemical expression and distribution of orexin, orphanin and leptin in the major salivary glands of some mammals
2012
Abstract: The aim of the study was to assess the involvement of apoptotic factors, cytokeratins and metalloproteinase- 9 in the histogenesis of both Epithelialized Gingival Lesions (EGL) and Periapical Lesions (PAL). 55 consecutive patients, 30 with PAL and 25 with EGL, were selected for the study after clinical and radiological examinations. The PAL patients had severe periapical lesions and tooth decay with exposure of the pulp chamber. All PAL and EGL biopsies were surgically extracted, fixed in 10% buffered formalin, and processed for routine light microscopy. Ten biopsies of each category were processed for immunohistochemistry (IHC). Serial paraffin sections were stained by IHC with a…
Season of birth effect in narcolepsy
2003
The causes of narcolepsy are unknown.1 Genetic factors such as positivity for HLA DR2 or certain genotypes of tumor necrosis factor–alpha or the orexin gene only explain a fraction of the risk. A season of birth effect has been observed in numerous studies for schizophrenia and bipolar disorder with a 10% excess of birth in winter and spring.2 Among the underlying factors discussed are infectious agents as well as seasonal variations in nutrition, light effects, and toxins.2 Most recently, the vitamin D hypothesis has been revisited.3 The production of vitamin D is associated with exposure to sunlight and the active 1,25 dihydroxyvitamin D3 is a potent modulator of immune functions,4 a dysf…
The next-generation liquid-scintillator neutrino observatory LENA
2012
We propose the liquid-scintillator detector LENA (Low Energy Neutrino Astronomy) as a next-generation neutrino observatory on the scale of 50 kt. The outstanding successes of the Borexino and KamLAND experiments demonstrate the large potential of liquid-scintillator detectors in low-energy neutrino physics. LENA's physics objectives comprise the observation of astrophysical and terrestrial neutrino sources as well as the investigation of neutrino oscillations. In the GeV energy range, the search for proton decay and long-baseline neutrino oscillation experiments complement the low-energy program. Based on the considerable expertise present in European and international research groups, the …
Final results of Borexino Phase-I on low-energy solar neutrino spectroscopy
2014
Borexino has been running since May 2007 at the Laboratori Nazionali del Gran Sasso laboratory in Italy with the primary goal of detecting solar neutrinos. The detector, a large, unsegmented liquid scintillator calorimeter characterized by unprecedented low levels of intrinsic radioactivity, is optimized for the study of the lower energy part of the spectrum. During Phase-I (2007–2010), Borexino first detected and then precisely measured the flux of the Be 7 solar neutrinos, ruled out any significant day-night asymmetry of their interaction rate, made the first direct observation of the pep neutrinos, and set the tightest upper limit on the flux of solar neutrinos produced in the CNO cycle …
Solar Neutrino Observables Sensitive to Matter Effects
2010
We discuss constraints on the coefficient A_{MSW} which is introduced to simulate the effect of weaker or stronger matter potential for electron neutrinos with the current and future solar neutrino data. The currently available solar neutrino data leads to a bound A_{MSW} = 1.47^{-0.42}_{+0.54} (^{-0.82}_{+1.88}) at 1\sigma (3\sigma) CL, which is consistent with the Standard Model prediction A_{MSW} = 1. For weaker matter potential (A_{MSW} 1), the bound is milder and is dominated by the day-night asymmetry of ^8B neutrino flux recently observed by Super-Kamiokande. Among the list of observable of ongoing and future solar neutrino experiments, we find that (1) an improved precision of the d…
Robust signatures of solar neutrino oscillation solutions
2001
With the goal of identifying signatures that select specific neutrino oscillation parameters, we test the robustness of global oscillation solutions that fit all the available solar and reactor experimental data. We use three global analysis strategies previously applied by different authors and also determine the sensitivity of the oscillation solutions to the critical nuclear fusion cross section, S_{17}(0), for the production of 8B. The favored solutions are LMA, LOW, and VAC in order of g.o.f. The neutral current to charged current ratio for SNO is predicted to be 3.5 +- 0.6 (1 sigma), which is separated from the no-oscillation value of 1.0 by much more than the expected experimental er…