Search results for "Original research"
showing 10 items of 2207 documents
The LuxR Regulators PcoR and RfiA Co-regulate Antimicrobial Peptide and Alginate Production in
2017
Cyclic lipopeptides (CLPs) are considered as some of the most important secondary metabolites in different plant-associated bacteria, thanks to their antimicrobial, cytotoxic, and surfactant properties. In this study, our aim was to investigate the role of the Quorum Sensing (QS) system, PcoI/PcoR, and the LuxR-type transcriptional regulator RfiA in CLP production in the phytopatogenic bacterium, Pseudomonas corrugata based on our previous work where we reported that the pcoR and rfiA mutants were devoid of the CLPs cormycin and corpeptin production. Due to the close genetic link between the QS system and the RfiA (rfiA is co-transcribed with pcoI), it was difficult to ascertain the specifi…
The Effects of Transcutaneous Spinal Direct Current Stimulation on Neuropathic Pain in Multiple Sclerosis: Clinical and Neurophysiological Assessment
2019
Background: Central neuropathic pain represents one of the most common symptoms in multiple sclerosis (MS) and it seriously affects quality of life. Spinal mechanisms may contribute to the pathogenesis of neuropathic pain in MS. Converging evidence from animal models and neurophysiological and clinical studies in humans suggests a potential effect of transcranial direct current stimulation (tc-DCS) on neuropathic pain. Spinal application of DCS, i.e., transcutaneous spinal DCS (ts-DCS), may modulate nociception through inhibition of spinal reflexes. Therefore, ts-DCS could represents an effective, safe and well-tolerated treatment for neuropathic pain in MS, a largely unexplored topic. This…
Comparing the Effect of Product-Based Metrics on the Translation Process
2021
Characteristics of the translation product are often used in translation process research as predictors for cognitive load, and by extension translation difficulty. In the last decade, user-activity information such as eye-tracking data has been increasingly employed as an experimental tool for that purpose. In this paper, we take a similar approach. We look for significant effects that different predictors may have on three different eye-tracking measures: First Fixation Duration (duration of first fixation on a token), Eye-Key Span (duration between first fixation on a token and the first keystroke contributing to its translation), and Total Reading Time on source tokens (sum of fixations…
Profiles of Nature Exposure and Outdoor Activities Associated With Occupational Well-Being Among Employees.
2018
This research addresses the profiles of nature exposure and outdoor activities in nature among Finnish employees (N = 783). The profiles were formed on the bases of nature exposure at work and the frequency and type of outdoor activities in nature engaged in during leisure time. The profiles were investigated in relation to work engagement and burnout. The latent profile analysis identified a five-class solution as the best model: High exposure (8%), Versatile exposure (22%), Unilateral exposure (38%), Average exposure (13%), and Low exposure (19%). An Analysis of Covariance (ANCOVA) was conducted for each well-being outcome in order to evaluate how the identified profiles related to occupa…
Promoting Students’ Health at University: Key Stakeholders, Cooperation, and Network Development
2021
Background: Cooperation among university units is considered a cornerstone for the promotion of students' health. The underlying mechanisms of health-promoting networks at universities have rarely been examined so far. Shedding light on partnerships is generally limited to the naming of allied actors in a network. Objectives and Methods: In this study, we used network analysis intending to visualize and describe the positions and characteristics of the network actors, and examine organizational relationships to determine the characteristics of the complete network. Results: The network analysis at hand provides in-depth insights into university structures promoting students' health comprisi…
On the dynamics of disobedience: experimental investigations of defying unjust authority.
2017
Across six Experimental conditions with university student participants (N=600), we examined some of the dynamics underlying expressed defiance to unjust authority. Results revealed disobedience was best enacted by participants low in right-wing authoritarianism and was more likely to occur when: 1) in physical proximity of other rebels, 2) the authority made two demanding requests instead of one, and 3) there had been an earlier opposition to injustice. Results are discussed within the theoretical framework of bounded rationality.
Toward a Dimensional Assessment of Externalizing Disorders in Children : Reliability and Validity of a Semi-Structured Parent Interview
2020
Objective: This study assesses the reliability and validity of the DSM-5-based, semi-structured Clinical Parent Interview for Externalizing Disorders in Children and Adolescents (ILF-EXTERNAL). Method: Participant data were drawn from the ongoing ESCAschool intervention study. The ILF-EXTERNAL was evaluated in a clinical sample of 474 children and adolescents (aged 6−12 years, 92 females) with symptoms of attention-deficit/hyperactivity disorder (ADHD). To obtain interrater reliability, the one-way random-effects, absolute agreement models of the intraclass correlation (ICC) for single ICC(1,1) and average measurements ICC(1,3) were computed between the interviewers and two independent rate…
Assessing Statistical Anxiety Among Online and Traditional Students
2019
The purpose of this study was to determine whether scores on the Statistical Anxiety Scale (SAS) manifest in the same way for students in online and traditional statistics courses. Tests of measurement invariance indicated that invariance of the two-factor model of the SAS held at every level. Therefore, we compared the statistical anxiety of online and traditional students. Results indicated that online and traditional statistics students reported comparable levels of anxiety with slightly less anxiety in terms of seeking help for traditional students. We concluded that online instruction is a viable form of statistics education at least for undergraduate students enrolled in the social sc…
A New Reliable Performance Analysis Template for Quantifying Action Variables in Elite Men’s Wheelchair Basketball
2019
This study aimed to develop a valid and reliable performance analysis template for quantifying team action variables in elite men’s wheelchair basketball. First action variables and operational definitions were identified by the authors and verified by an expert panel of wheelchair basketball coaching staff in order to establish expert validity. A total of 109 action variable were then placed into 17 agreed Categorical Predictor Variable categories. The action variables were then used to develop a computerized performance analysis template for post-event analysis. Each possession (n = 200) from an international men’s wheelchair basketball game was analyzed by the first author on two occasio…
Psychometric testing of the Norwegian version of the questionnaire Family Satisfaction in the Intensive Care Unit (FS-ICU-24)
2018
Bjørg Dale,1 Gro Frivold2 1Centre for Caring Research, Southern Norway, University of Agder, Faculty of Health and Sport Sciences, Grimstad, Norway; 2University of Agder, Faculty of Health and Sport Sciences, Grimstad, Norway Introduction: The questionnaire, Family Satisfaction in the Intensive Care Unit (FS-ICU-24), was developed to assess relatives’ satisfaction with care and involvement in decision-making processes when a close family member stays in the ICU Aim: This study was aimed at describing the translation and exploring the psychometric properties of the Norwegian version of the questionnaire. Methods: The study design was a cross-sectional survey. After trans…