Search results for "Otter"

showing 10 items of 192 documents

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

2016

Background Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants identified to date also associate with risk of CHD in a prospective setting. Methods We performed a two-stage GWAS analysis of incident myocardial infarction (MI) and CHD in a total of 64,297 individuals (including 3898 MI cases, 5465 CHD cases). SNPs that passed an arbitrary threshold of 5×10−6 in Stage I were taken to Stage II for further discovery. Furthermore, in an analysis of prognosis, we studied whether known SNPs from former GWAS were associated with total mortality in individuals who experienced MI during follow-up. Res…

Male0301 basic medicineOncologyPREDICTIONMyocardial Infarctionlcsh:MedicineGenome-wide association studyCoronary Artery DiseaseCardiovascular MedicineSUSCEPTIBILITY030204 cardiovascular system & hematologyCardiovascularBioinformaticsincident myocardial infarctionCohort StudiesCoronary artery diseaseMathematical and Statistical Techniques0302 clinical medicineDESIGNMedicine and Health Sciences2.1 Biological and endogenous factorsProspective StudiesMyocardial infarctionAetiologyCooperative Behaviorlcsh:ScienceProspective cohort studyRISKscreening and diagnosisMultidisciplinaryResearch Support Non-U.S. Gov'tSingle NucleotideGenomicsMiddle Aged3. Good healthMultidisciplinary SciencesDetectionCHROMOSOME 9P21Heart DiseaseResearch DesignCardiovascular DiseasesCARDIOVASCULAR-DISEASEPhysical SciencesScience & Technology - Other TopicsFemaleStatistics (Mathematics)4.2 Evaluation of markers and technologiesResearch ArticleCohort studymedicine.medical_specialtyGeneral Science & TechnologyCardiologySingle-nucleotide polymorphismResearch and Analysis MethodsGenome ComplexityPolymorphism Single Nucleotide03 medical and health sciencescoronary hearth diseaseInternal medicineMD MultidisciplinaryGenome-Wide Association StudiesGeneticsJournal ArticlemedicineHumansSNPGenetic Predisposition to DiseasePolymorphismStatistical MethodsHeart Disease - Coronary Heart DiseaseMETAANALYSISAgedGenetic associationta112Science & Technologybusiness.industryPreventionlcsh:RHuman GenomeBiology and Life SciencesComputational BiologyHuman GeneticsGenome AnalysisROTTERDAMmedicine.diseaseIntronsGood Health and Well Being030104 developmental biologyGenetic LociGenetics of Diseaselcsh:Q3111 BiomedicinebusinessMathematicsMeta-AnalysisGenome-Wide Association StudyPLOS ONE
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The beaker phenomenon and the Genomic transformations of Northwest Europe

2018

Bell Beaker pottery spread across western and central Europe beginning around 2750 BCE before disappearing between 2200–1800 BCE. The mechanism of its expansion is a topic of long-standing debate, with support for both cultural diffusion and human migration. We present new genome-wide ancient DNA data from 170 Neolithic, Copper Age and Bronze Age Europeans, including 100 Beaker-associated individuals. In contrast to the Corded Ware Complex, which has previously been identified as arriving in central Europe following migration from the east, we observe limited genetic affinity between Iberian and central European Beaker Complex-associated individuals, and thus exclude migration as a signific…

Male0301 basic medicineSteppeADNNéolithiqueBell BeakerArqueologiaBell Beaker culturegenome wide ancient DNA0302 clinical medicineArchéologiePhenomenonddc:5500601 history and archaeologySuisseHistory Ancient0303 health scienceseducation.field_of_studygeography.geographical_feature_categoryMultidisciplinary060102 archaeology[SDE.IE]Environmental Sciences/Environmental EngineeringHuman migrationPréhistoireNeolithic periodGene PoolGenomics[SHS.GEO]Humanities and Social Sciences/Geography06 humanities and the artsbell BeakerEuropeGeographyArchaeologyCeràmicaEthnologyMégalithisme1000ArchaeogeneticsCampaniformePotteryHuman Migration[SDE.MCG]Environmental Sciences/Global ChangesPopulationAncient historyArticle03 medical and health sciencesSpatio-Temporal Analysispopular geneticsBronze AgeBeakerCultural EvolutionNeolíticgenomicsHumansDNA Ancienteducation030304 developmental biologyChromosomes Human YGenome Humanbusiness.industryNorthwest Europebell Beaker; genome wide ancient DNA; EuropeChalcolithic[SDE.ES]Environmental Sciences/Environmental and SocietyAncient DNAGenetics Population030104 developmental biologyHaplotypesPeriod (geology)GenomicPottery[SDE.BE]Environmental Sciences/Biodiversity and Ecologybusiness030217 neurology & neurosurgery
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Genome-wide association study of PR interval.

2009

The electrocardiographic PR interval reflects atrial and atrioventricular nodal conduction, disturbances of which increase risk of atrial fibrillation (AF). To identify underlying common genetic variation, we meta-analyzed genome-wide association results for PR interval from seven community-based studies of European-ancestry individuals in the CHARGE consortium: AGES, ARIC, CHS, FHS, KORA, Rotterdam Study, and SardiNIA (N=28,517). Statistically significant loci (P<5×10-8) were tested for association with AF (N=5,741 cases). We identified nine loci associated with PR interval. At chromosome 3p22.2, we observed two independent associations in voltage gated sodium channel genes SCN10A and SCN5…

MaleCandidate genePopulationvoltage gated sodium channelGenome-wide association studyLocus (genetics)030204 cardiovascular system & hematologyBiologyArticleCohort Studiesquantitative trait03 medical and health sciencesRotterdam StudyElectrocardiography0302 clinical medicineMeta-Analysis as TopicHeart Conduction SystemAtrial FibrillationGeneticsmedicineHumansGenetic Predisposition to Diseasecardiovascular diseasesPR intervaleducation030304 developmental biologyGenetic associationAgedGeneticsdevelopmental genes0303 health scienceseducation.field_of_studygenome-wide association studyPQ intervalAtrial fibrillationmedicine.diseaseGenetic Locicardiovascular systemPR intervalFemaleNature genetics
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Status of Corynosoma (Acanthocephala: Polymorphidae) based on anatomical, ecological, and phylogenetic evidence, with the erection of Pseudocorynosom…

2006

The possession of genital spines has been considered as a key taxonomic trait to differentiate Corynosoma from other genera of the Polymorphidae. However, Corynosoma currently consists of 2 groups of species with clear ecological and morphological divergences: the "marine" group (with ca. 30 species) infects mammals and piscivorous birds in the marine realm, whereas the "freshwater" group (with ca. 7 species) infects waterfowl in continental waters. Species from these groups differ in shape of body and neck, trunk spination, lemnisci length and shape, testes arrangement, and number and shape of cement glands. We tested whether species from these 2 groups formed a monophyletic assemblage bas…

MaleZoologyFresh WaterAcanthocephalaHost-Parasite InteractionsPolymorphidaeBirdsMonophylyWaterfowlAnimalsAmphipodaSeawaterPseudocorynosomaEcology Evolution Behavior and SystematicsPhylogenyPhylogenetic treebiologyEcologyBird Diseasesbiology.organism_classificationPolymorphusCaniformiaDucksMinkKey (lock)ParasitologyFemaleCetaceaHelminthiasis AnimalAcanthocephalaOttersThe Journal of parasitology
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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

2011

Objective: To address the need for standardization of osteoarthritis (OA) phenotypes by examining the effect of heterogeneity among symptomatic (SOA) and radiographic osteoarthritis (ROA) phenotypes. Methods: Descriptions of OA phenotypes of the 28 studies involved in the TREAT-OA consortium were collected. We investigated whether different OA definitions result in different association results by creating various hip OA definitions in one large population based cohort (the Rotterdam Study I (RSI)) and testing those for association with gender, age and body mass index using one-way ANOVA. For ROA, we standardized the hip-, knee- and hand ROA definitions and calculated prevalence&#39;s of RO…

Malenivelrikkomedicine.medical_specialtygenetiikkaBiomedical EngineeringMEDLINEdiagnostiset kriteeritOsteoarthritisbehavioral disciplines and activitiesArticleCohort Studies03 medical and health sciencesRotterdam Study0302 clinical medicineRheumatologyInternal medicineTREATOAOsteoarthritismedicinePrevalenceGeneticsHumansOrthopedics and Sports Medicine030304 developmental biologyRheumatology and Autoimmunity2. Zero hunger030203 arthritis & rheumatology0303 health sciencesAnalysis of Varianceperinnöllisyystiedebusiness.industryCase-control studyDefinitionReference Standardsmedicine.diseaseGenetics Osteoarthritis Phenotype Definition TREATOA genome-wide association radiographic hip osteoarthritis bone-mineral density knee osteoarthritis hand osteoarthritis osteoporotic fractures general-population joint involvement risk-factors susceptibilityRheumatology3. Good healthPhenotypeCase-Control Studiesdiagnostic criteriaCohortPhysical therapyFemalebusinessBody mass indexCohort study
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Electrochemical discrimination of manufacturing types of pottery from Magna Mater Temple and Fora of Nerva and Caesar (Rome, Italy)

2018

Abstract The voltammetry of immobilized microparticles (VIMP) methodology is applied to a series of pottery samples from the Roman sites of Nerva's Forum (second half of 9th-early 11th A.D), Caesar's Forum (second half of 9th-early 11th A.D) and Magna Mater Temple (III century). The VIMP sampling applied to voltammetric and electrochemical impedance spectroscopy (EIS) measurements was applied by the first time to acquire archaeometric information on archaeological pottery. VIMP measurements using pressed sample pellets on gold electrodes in contact with air-saturated 0.10 M H2SO4 have permitted to detect voltammetric signals for the reduction/oxidation of Fe and Mn minerals as well as catal…

Materials scienceMetallurgy020101 civil engineeringGeology02 engineering and technology021001 nanoscience & nanotechnologyElectrochemistry0201 civil engineeringDielectric spectroscopyarchaeometry; electrochemical impedance spectroscopy; pottery; solid state voltammetry; geology; geochemistry and petrologymedicine.anatomical_structureGeochemistry and PetrologyTemplemedicineOxygen reduction reactionArchaeological potteryPottery0210 nano-technologyVoltammetryGraphite electrodeApplied Clay Science
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Non-invasive investigation on pigments of the Aeolian Islands Neolithic pottery

2023

The Neolithic painted pottery, spread all over southern Italy, is considered as an important chronological indicator for the development of VI-V millennium BC prehistoric settlements and cultural traditions. The goal of this work is to contribute to the study of this ceramic class through the chemical characterization of some samples coming from the Aeolian Islands. 16 different sherds have been selected and the pigments preserved in their decorations analyzed via non-invasive techniques: Fiber Optical Reflectance Spectroscopy (FORS), X-ray Fluorescence (XRF), Raman Spectroscopy and Infrared Spectroscopy (FT-IR). The different pigments, some of which no longer clearly visible to the naked e…

Mechanics of MaterialsMechanical EngineeringNeolithic painted potteryNon-invasive measurementsHematiteGeneral Materials ScienceCondensed Matter PhysicsSettore CHIM/12 - Chimica Dell'Ambiente E Dei Beni CulturaliSettore CHIM/02 - Chimica Fisica
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Lo scavo della Chiesa di Santa Maria Degli Angeli alla Gancia: indicatori archeologici della prima età islamica a Palermo

2014

Lo scavo in occasione del restauro della chiesa di Santa Maria degli Angeli alla Gancia a Palermo ha permesso di recuperare alcune stratigrafie affidabili relative alla prima età islamica a Palermo. Lo studio della ceramica ha restituito una serie di indicatori cronologici per il IX-X secolo nonché di proporre nuove cronologie per alcune classi di materiali. Relativamente alla storia della città questo scavo ha aggiunto alcune note importanti che riguardano il porto e la cittadella e mirale la al-Halisah.

Medieval pottery islamic pottery Palermo early islamic SicilyCeramica medievale anfore ceramica da fuoco medievale Palermo islamica Palermo medievaleSettore L-ANT/08 - Archeologia Cristiana E Medievale
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Spatial and Temporal Diversity During the Neolithic Spread in the Western Mediterranean: The First Pottery Productions

2017

Actual research into the neolithization process and the development of farming communities in the Western Mediterranean reveals a diverse and complex cultural landscape. Dispersal routes and rhythm of diffusion of the agro-pastoral economy, Mesolithic inheritance, regional interactions between communities, and functional adaptations all have to be explored to trace how Mediterranean societies were reshaped during this period. The different pottery traditions that accompany the Neolithic spread and its economic development are of course interconnected (the “impressed ware”), but they also show some degree of polymorphism. This variability has been variously interpreted, but rarely quantified…

Mediterranean climate010506 paleontology[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory060102 archaeologyEcologyCultural landscape06 humanities and the arts01 natural sciencesArchaeologyTemporal diversityGeographyPeriod (geology)Biological dispersal0601 history and archaeologyPotterySociocultural evolutionComputingMilieux_MISCELLANEOUSMesolithic0105 earth and related environmental sciences
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New insights into Early Celtic consumption practices: Organic residue analyses of local and imported pottery from Vix-Mont Lassois

2019

The rich Mediterranean imports found in Early Celtic princely sites (7th-5th cent. BC) in Southwestern Germany, Switzerland and Eastern France have long been the focus of archaeological and public interest. Consumption practices, particularly in the context of feasting, played a major role in Early Celtic life and imported ceramic vessels have consequently been interpreted as an attempt by the elite to imitate Mediterranean wine feasting. Here we present the first scientific study carried out to elucidate the use of Mediterranean imports in Early Celtic Central Europe and their local ceramic counterparts through organic residue analyses of 99 vessels from Vix-Mont Lassois, a key Early Celti…

Mediterranean climate10108 Institute of ArchaeologyCeramicsWineBiochemistryAgricultural economicsFatsAnimal ProductsGermanyMedicine and Health SciencesBeeswaxVitis0601 history and archaeologyMaterials0303 health sciencesMultidisciplinaryGreece060102 archaeologyAlcoholic BeveragesQREukaryotafood and beveragesAgriculture06 humanities and the artsPlantsLipidsEuropeGeographyArchaeologyPhysical SciencesMedicineFranceOrganic Materials900 HistorySwitzerlandResearch ArticleMilletCeltic languagesScienceMaterials Science1100 General Agricultural and Biological SciencesBeverages03 medical and health sciences1300 General Biochemistry Genetics and Molecular BiologyAnimalsHumansPlant OilsGrassesMilletsNutrition030304 developmental biologyWineBeehive1000 Multidisciplinary[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryConsumption practicesOrganismsBiology and Life SciencesFeeding BehaviorDietWaxesGrape winePotteryEdible GrainOilsScientific studyPLOS ONE
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