Search results for "P.H.S."

First-trimester maternal concentrations of polyfluoroalkyl substances and fetal growth throughout pregnancy

2019

Background: Several studies have investigated the possible association between prenatal exposure to perfluoroalkyl substances (PFASs) and birth anthropometry. However, none has assessed fetal size longitudinally. We studied the possible association between PFASs and fetal biometry. Methods: In 1230 mother-child pairs of three cohorts from the Spanish INMA-Project, we analyzed perfluorohexanesulfonic acid (PFHxS), perfluorooctanesulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluorononanoic acid (PFNA) in first-trimester maternal plasma (collection: 2003-2008). We measured abdominal circumference (AC), femur length (FL), biparietal diameter (BPD), and estimated fetal weight (EFW)…

Epigenetic differences arise during the lifetime of monozygotic twins.

2005

Monozygous twins share a common genotype. However, most monozygotic twin pairs are not identical; several types of phenotypic discordance may be observed, such as differences in susceptibilities to disease and a wide range of anthropomorphic features. There are several possible explanations for these observations, but one is the existence of epigenetic differences. To address this issue, we examined the global and locus-specific differences in DNA methylation and histone acetylation of a large cohort of monozygotic twins. We found that, although twins are epigenetically indistinguishable during the early years of life, older monozygous twins exhibited remarkable differences in their overall…

Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab.

2018

Background Autoimmune thrombotic thrombocytopenic purpura (iTTP) is caused by autoantibody-mediated severe a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13 (ADAMTS13) deficiency leading to micro-angiopathic haemolytic anaemia (MAHA) and thrombocytopenia with organ damage. Patients survive with plasma exchange (PEX), fresh frozen plasma replacement and corticosteroid treatment. Anti-CD20 monoclonal antibody rituximab is increasingly used in patients resistant to conventional PEX or relapsing after an acute bout. Objective This retrospective observational study focused on the relapse rate and possible influencing factors including treatment with rituximab first…

Assessment of Kinect V2 for elbow range of motion estimation in people with haemophilia using an angle correction model

2018

Introduction The joint range of motion (ROM) is an important clinical parameter used to assess the loss of functionality resulting from joint bleedings in people with haemophilia. These episodes require a close follow-up and, to decrease patients' hospital dependence, telemedicine tools are needed. Therefore, this study is aimed to analyse the validity of the Microsoft Kinect V2 sensor with corrected angle measurement to be used in the monitoring of elbow ROM in people with haemophilia. Methods A convenience sample of 10 healthy controls (CG) and 10 patients with haemophilia with elbow arthropathy (HG) participated in this study. Full ROM of elbow joints was measured in the frontal view wit…

Resectoscope versus small diameter hysteroscopy for endometrial polypectomy in patients with "unfavorable" cervix

2017

BACKGROUND: The aim of this study was to compare resectoscopic and small-diameter hysteroscopic techniques for endometrial polypectomy in patients with "unfavorable" cervix.METHODS: Eighty women with a single 2-4 cm sized endometrial polyp, with unfavorable cervical anatomical conditions were enrolled in the study. Forty patients were treated with a 26F resectoscope requiring cervical dilatation (group A), forty patients were treated with a 5-mm hysteroscope requiring vaginoscopic approach (group B). Operative time, fluid absorption, complications, instrument failure, postoperative pain, overnight stay were analyzed. Operative visualization, operative difficulty and overall surgeon's satisf…

Demokratia tekee meistä älykkäitä

2018

Aproximación al sistema impositivo de la Generalidad: el tall del drap en el área alicantina (siglos XIV y XV)

1986

La clasificacion de los impuestos puede hacerse, al menos, desde dos puntos de vista: en base a la titularidad o al concepto. La viabilidad de la primera ha sido puesta en crisis por algunos autores que se inclinan por la segunda (1). La utilidad de esta ultima es, a nuestro juicio, indudable, pero requiere, en el confuso panorama de los impuestos medievales valencianos, una definicion previa de los conceptos impositivos que permita la mencionada clasificacion.

Muons in air showers at the Pierre Auger Observatory: Measurement of atmospheric production depth

2014

The surface detector array of the Pierre Auger Observatory provides information about the longitudinal development of the muonic component of extensive air showers. Using the timing information from the flash analog-to-digital converter traces of surface detectors far from the shower core, it is possible to reconstruct a muon production depth distribution. We characterize the goodness of this reconstruction for zenith angles around 60° and different energies of the primary particle. From these distributions, we define Xμmax as the depth along the shower axis where the production of muons reaches maximum. We explore the potentiality of Xμmax as a useful observable to infer the mass compositi…

Temperature-based and radiance-based validations of the V5 MODIS land surface temperature product

2009

[1] The V5 level 2 land surface temperature (LST) product of the Moderate Resolution Imaging Spectroradiometer (MODIS) was validated over homogeneous rice fields in Valencia, Spain, and the Hainich forest in Germany. For the Valencia site, ground LST measurements were compared with the MOD11_L2 product in the conventional temperature-based (T-based) method. We also applied the alternative radiance-based (R-based) method, with in situ LSTs calculated from brightness temperatures in band 31 through radiative transfer simulations using temperature and water vapor profiles and surface emissivity data. At the Valencia site, profiles were obtained from local radiosonde measurements and from Natio…

Using HYDRUS-2D model to assess the optimal drip lateral depth for eggplant crop in a sandy loam soil of central Tunisia

2016

The main objective of the work is to assess the optimal drip lateral depth for Eggplant crop (Solanum melongena L.) irrigated with a drip system in a sandy loam soil by means of field measurements and simulation models. Initially, the performance of Hydrus-2D was assessed based on the comparison between simulated soil water contents (SWC) and the corresponding measured in two plots, in which laterals with co-extruded emitters were laid on the soil surface (drip irrigation, DI-0) and at 20 cm depth (subsurface drip irrigation, SDI-20), respectively. In order to identify the optimal position of the lateral, the results of different scenarios, obtained by changing the installation depth of the…