Search results for "PAM"
showing 10 items of 1768 documents
Influència de Kohlberg en el programa de compromís social del centre penitenciari d' "El Dueso"
2018
espanolTras anos de innovacion i puesta en practica de diferentes formas de intervencion en el mundo penitenciario, en el Centro Penitenciario de El Dueso se aplica el programa de Compromiso Social. La Teoria del Desarrollo Moral de Kohlberg esta sirviendo de apoyo para potenciar la prosocialidad asi como el desarrollo moral de los internos a traves de aquellas actividades en las que se convierten en protagonistas de la ayuda a terceras personas, promoviendo su propio cambio personal i generando un proceso de reciprocidad con el exterior de la prision. Se defienden las actividades de tipo prosocial como excelente herramienta de trabajo en las prisiones. catalaDespres d’anys d’innovacio i de…
Assessing the Effect of the Economy for the Common Good System on Business Performance
2023
Extant literature has pointed to organizational hybridity to lever sustainable business transformation. Moreover, some authors hold that there is a possible trade-off between sustainability and performance. However, there is still little empirical evidence on the impact that such sustainability-driven hybridization systems have on performance. Thus, the present study’s main goal is to fill this gap by providing empirical evidence on the impact of the implementation of the Economy for the Common Good, as a sustainability-driven organizational system, on business performance. To do so, the authors relied on a sample of 206 businesses from five European countries. Then, the authors follo…
Procesado y análisis de datos ambientales (2009/2010)
2009
Utilización de sistemas informáticos para el diseño de estaciones de tratamiento de aguas residuales
1994
Los sistemas informáticos para el diseño de Estaciones de Tratamiento de Aguas Residuales (ETAR) resultan de gran utilidad para la toma de decisiones relacionadas con la gestión de la calidad del agua en el medio natural. En este artículo se presenta el sistema DATAR, desarrollado para el diseño completo y riguroso de una ETAR que cumpla las especificaciones impuestas al vertido. Para ello se han desarrollado modelos matemáticos que describen los procesos que tienen lugar en los distintos elementos de tratamiento considerando los parámetros de calidad demanda biológica de oxígeno a los 5 días (DBO5), demanda química de oxígeno (DQO), sólidos suspendidos (SS), nitrógeno Kjeldhal (NKT) y fósf…
Drug-induced expansion and differentiation of Vγ9Vδ2 T cells in vivo: The role of exogenous IL-2
2005
Human Vgamma9Vdelta2 T cells recognize nonpeptidic Ags generated by the 1-deoxy-d-xylulose 5-phosphate (many eubacteria, algae, plants, and Apicomplexa) and mevalonate (eukaryotes, archaebacteria, and certain eubacteria) pathways of isoprenoid synthesis. The potent Vgamma9Vdelta2 T cell reactivity 1) against certain cancer cells or 2) induced by infectious agents indicates that therapeutic augmentations of Vgamma9Vdelta2 T cell activities may be clinically beneficial. The functional characteristics of Vgamma9Vdelta2 T cells from Macaca fascicularis (cynomolgus monkey) are very similar to those from Homo sapiens. We have found that the i.v. administration of nitrogen-containing bisphosphonat…
Revisiting the controversial role of salsolinol in the neurobiological effects of ethanol: old and new vistas.
2011
The possible involvement of salsolinol (Sal), an endogenous condensation product of ACD (the first metabolite of ethanol) and dopamine, in the neurochemical basis underlying ethanol action has been repeatedly suggested although it has not been unequivocally established, still being a controversial matter of debate. The main goal of this review is to evaluate the presumed contribution of Sal to ethanol effects summarizing the reported data since the discovery in the 1970s of Sal formation in vitro during ethanol metabolism until the more recent studies characterizing its behavioral and neurochemical effects. Towards this end, we first analyze the production and detection of Sal, in different…
Topologically Controlled Inter-Polyelectrolyte Complexes between Molecular Bottlebrushes and Dendrimers
2010
The complexation of a cylindrical polyelectrolyte−brush-surfactant complex (PMMPSS−C12) and an oppositely charged generation-5 PAMAM dendrimer (G5-PAMAM) in methanol (MeOH) leads to kinetically con...
Old and New Drugs for Treatment of Advanced Heart Failure.
2020
Background: Advanced heart failure (HF) is a progressive disease with high mortality and limited medical therapeutic options. Long-term mechanical circulatory support and heart transplantation remain goldstandard treatments for these patients; however, access to these therapies is limited by the advanced age and multiple comorbidities of affected patients, as well as by the limited number of organs available. Methods: Traditional and new drugs available for the treatment of advanced HF have been researched. Results: To date, the cornerstone for the treatment of patients with advanced HF remains water restriction, intravenous loop diuretic therapy and inotropic support. However, many patien…
Phenothiazines interfere with dopaminergic neurodegeneration in Caenorhabditis elegans models of Parkinson's disease
2010
Oxidative stress is involved in the pathogenesis of various neurodegenerative disorders, conventional antioxidant strategies have yet been of limited success. We have employed transgenic Caenorhabditis elegans expressing DsRed2 in dopaminergic neurons and CFP pan-neuronally, to characterize in larval and adult animals the effects of rotenone and 1-methyl-4-phenyl-pyridinium (MPP(+)) on the dopaminergic system. Investigating the antioxidant phenothiazine and different derived antipsychotic drugs, it was found that free phenothiazine exerted strong neuroprotection at the cellular level and resulted in a better performance in behavioral assays, whereas apomorphine and other dopamine agonists o…